6PVA

The structure of NTMT1 in complex with compound 11

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006338	biological_process	chromatin remodeling
B	0006480	biological_process	N-terminal protein amino acid methylation
B	0007051	biological_process	spindle organization
B	0007059	biological_process	chromosome segregation
B	0008168	molecular_function	methyltransferase activity
B	0008276	molecular_function	protein methyltransferase activity
B	0018013	biological_process	N-terminal peptidyl-glycine methylation
B	0018016	biological_process	N-terminal peptidyl-proline dimethylation
B	0032259	biological_process	methylation
B	0035572	biological_process	N-terminal peptidyl-serine dimethylation
B	0035573	biological_process	N-terminal peptidyl-serine trimethylation
B	0042054	molecular_function	histone methyltransferase activity
B	0071885	molecular_function	N-terminal protein N-methyltransferase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:26543159, ECO:0000269|PubMed:26543161, ECO:0007744|PDB:2EX4, ECO:0007744|PDB:5CVD, ECO:0007744|PDB:5CVE, ECO:0007744|PDB:5E1D, ECO:0007744|PDB:5E1M, ECO:0007744|PDB:5E1O, ECO:0007744|PDB:5E2A, ECO:0007744|PDB:5E2B

Chain	Residue	Details
B	GLY69
B	ARG74
B	ASP91
B	LEU119
B	GLN135

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N-acetylthreonine; in N-terminal Xaa-Pro-Lys N-methyltransferase 1, N-terminally processed => ECO:0000269|Ref.5, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895

Chain	Residue	Details
B	THR2

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