6PV6
Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002027 | biological_process | regulation of heart rate |
| A | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
| A | 0005102 | molecular_function | signaling receptor binding |
| A | 0005246 | molecular_function | calcium channel regulator activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005528 | molecular_function | FK506 binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006458 | biological_process | 'de novo' protein folding |
| A | 0006939 | biological_process | smooth muscle contraction |
| A | 0007204 | biological_process | positive regulation of cytosolic calcium ion concentration |
| A | 0009749 | biological_process | response to glucose |
| A | 0010459 | biological_process | negative regulation of heart rate |
| A | 0010880 | biological_process | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum |
| A | 0010881 | biological_process | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion |
| A | 0016020 | cellular_component | membrane |
| A | 0016529 | cellular_component | sarcoplasmic reticulum |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0019227 | biological_process | neuronal action potential propagation |
| A | 0019722 | biological_process | calcium-mediated signaling |
| A | 0019855 | molecular_function | calcium channel inhibitor activity |
| A | 0030018 | cellular_component | Z disc |
| A | 0030073 | biological_process | insulin secretion |
| A | 0033017 | cellular_component | sarcoplasmic reticulum membrane |
| A | 0034704 | cellular_component | calcium channel complex |
| A | 0035773 | biological_process | insulin secretion involved in cellular response to glucose stimulus |
| A | 0042026 | biological_process | protein refolding |
| A | 0042098 | biological_process | T cell proliferation |
| A | 0044325 | molecular_function | transmembrane transporter binding |
| A | 0050849 | biological_process | negative regulation of calcium-mediated signaling |
| A | 0051209 | biological_process | release of sequestered calcium ion into cytosol |
| A | 0051280 | biological_process | negative regulation of release of sequestered calcium ion into cytosol |
| A | 0051284 | biological_process | positive regulation of sequestering of calcium ion |
| A | 0051604 | biological_process | protein maturation |
| A | 0051775 | biological_process | response to redox state |
| A | 0061179 | biological_process | negative regulation of insulin secretion involved in cellular response to glucose stimulus |
| B | 0005216 | molecular_function | monoatomic ion channel activity |
| B | 0005219 | molecular_function | ryanodine-sensitive calcium-release channel activity |
| B | 0005262 | molecular_function | calcium channel activity |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0006816 | biological_process | calcium ion transport |
| B | 0006874 | biological_process | intracellular calcium ion homeostasis |
| B | 0016020 | cellular_component | membrane |
| B | 0055085 | biological_process | transmembrane transport |
| B | 0070588 | biological_process | calcium ion transmembrane transport |
| E | 0005216 | molecular_function | monoatomic ion channel activity |
| E | 0005219 | molecular_function | ryanodine-sensitive calcium-release channel activity |
| E | 0005262 | molecular_function | calcium channel activity |
| E | 0006811 | biological_process | monoatomic ion transport |
| E | 0006816 | biological_process | calcium ion transport |
| E | 0006874 | biological_process | intracellular calcium ion homeostasis |
| E | 0016020 | cellular_component | membrane |
| E | 0055085 | biological_process | transmembrane transport |
| E | 0070588 | biological_process | calcium ion transmembrane transport |
| F | 0002027 | biological_process | regulation of heart rate |
| F | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
| F | 0005102 | molecular_function | signaling receptor binding |
| F | 0005246 | molecular_function | calcium channel regulator activity |
| F | 0005515 | molecular_function | protein binding |
| F | 0005528 | molecular_function | FK506 binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0006458 | biological_process | 'de novo' protein folding |
| F | 0006939 | biological_process | smooth muscle contraction |
| F | 0007204 | biological_process | positive regulation of cytosolic calcium ion concentration |
| F | 0009749 | biological_process | response to glucose |
| F | 0010459 | biological_process | negative regulation of heart rate |
| F | 0010880 | biological_process | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum |
| F | 0010881 | biological_process | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion |
| F | 0016020 | cellular_component | membrane |
| F | 0016529 | cellular_component | sarcoplasmic reticulum |
| F | 0016853 | molecular_function | isomerase activity |
| F | 0019227 | biological_process | neuronal action potential propagation |
| F | 0019722 | biological_process | calcium-mediated signaling |
| F | 0019855 | molecular_function | calcium channel inhibitor activity |
| F | 0030018 | cellular_component | Z disc |
| F | 0030073 | biological_process | insulin secretion |
| F | 0033017 | cellular_component | sarcoplasmic reticulum membrane |
| F | 0034704 | cellular_component | calcium channel complex |
| F | 0035773 | biological_process | insulin secretion involved in cellular response to glucose stimulus |
| F | 0042026 | biological_process | protein refolding |
| F | 0042098 | biological_process | T cell proliferation |
| F | 0044325 | molecular_function | transmembrane transporter binding |
| F | 0050849 | biological_process | negative regulation of calcium-mediated signaling |
| F | 0051209 | biological_process | release of sequestered calcium ion into cytosol |
| F | 0051280 | biological_process | negative regulation of release of sequestered calcium ion into cytosol |
| F | 0051284 | biological_process | positive regulation of sequestering of calcium ion |
| F | 0051604 | biological_process | protein maturation |
| F | 0051775 | biological_process | response to redox state |
| F | 0061179 | biological_process | negative regulation of insulin secretion involved in cellular response to glucose stimulus |
| G | 0005216 | molecular_function | monoatomic ion channel activity |
| G | 0005219 | molecular_function | ryanodine-sensitive calcium-release channel activity |
| G | 0005262 | molecular_function | calcium channel activity |
| G | 0006811 | biological_process | monoatomic ion transport |
| G | 0006816 | biological_process | calcium ion transport |
| G | 0006874 | biological_process | intracellular calcium ion homeostasis |
| G | 0016020 | cellular_component | membrane |
| G | 0055085 | biological_process | transmembrane transport |
| G | 0070588 | biological_process | calcium ion transmembrane transport |
| H | 0002027 | biological_process | regulation of heart rate |
| H | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
| H | 0005102 | molecular_function | signaling receptor binding |
| H | 0005246 | molecular_function | calcium channel regulator activity |
| H | 0005515 | molecular_function | protein binding |
| H | 0005528 | molecular_function | FK506 binding |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0006458 | biological_process | 'de novo' protein folding |
| H | 0006939 | biological_process | smooth muscle contraction |
| H | 0007204 | biological_process | positive regulation of cytosolic calcium ion concentration |
| H | 0009749 | biological_process | response to glucose |
| H | 0010459 | biological_process | negative regulation of heart rate |
| H | 0010880 | biological_process | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum |
| H | 0010881 | biological_process | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion |
| H | 0016020 | cellular_component | membrane |
| H | 0016529 | cellular_component | sarcoplasmic reticulum |
| H | 0016853 | molecular_function | isomerase activity |
| H | 0019227 | biological_process | neuronal action potential propagation |
| H | 0019722 | biological_process | calcium-mediated signaling |
| H | 0019855 | molecular_function | calcium channel inhibitor activity |
| H | 0030018 | cellular_component | Z disc |
| H | 0030073 | biological_process | insulin secretion |
| H | 0033017 | cellular_component | sarcoplasmic reticulum membrane |
| H | 0034704 | cellular_component | calcium channel complex |
| H | 0035773 | biological_process | insulin secretion involved in cellular response to glucose stimulus |
| H | 0042026 | biological_process | protein refolding |
| H | 0042098 | biological_process | T cell proliferation |
| H | 0044325 | molecular_function | transmembrane transporter binding |
| H | 0050849 | biological_process | negative regulation of calcium-mediated signaling |
| H | 0051209 | biological_process | release of sequestered calcium ion into cytosol |
| H | 0051280 | biological_process | negative regulation of release of sequestered calcium ion into cytosol |
| H | 0051284 | biological_process | positive regulation of sequestering of calcium ion |
| H | 0051604 | biological_process | protein maturation |
| H | 0051775 | biological_process | response to redox state |
| H | 0061179 | biological_process | negative regulation of insulin secretion involved in cellular response to glucose stimulus |
| I | 0005216 | molecular_function | monoatomic ion channel activity |
| I | 0005219 | molecular_function | ryanodine-sensitive calcium-release channel activity |
| I | 0005262 | molecular_function | calcium channel activity |
| I | 0006811 | biological_process | monoatomic ion transport |
| I | 0006816 | biological_process | calcium ion transport |
| I | 0006874 | biological_process | intracellular calcium ion homeostasis |
| I | 0016020 | cellular_component | membrane |
| I | 0055085 | biological_process | transmembrane transport |
| I | 0070588 | biological_process | calcium ion transmembrane transport |
| J | 0002027 | biological_process | regulation of heart rate |
| J | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
| J | 0005102 | molecular_function | signaling receptor binding |
| J | 0005246 | molecular_function | calcium channel regulator activity |
| J | 0005515 | molecular_function | protein binding |
| J | 0005528 | molecular_function | FK506 binding |
| J | 0005737 | cellular_component | cytoplasm |
| J | 0006458 | biological_process | 'de novo' protein folding |
| J | 0006939 | biological_process | smooth muscle contraction |
| J | 0007204 | biological_process | positive regulation of cytosolic calcium ion concentration |
| J | 0009749 | biological_process | response to glucose |
| J | 0010459 | biological_process | negative regulation of heart rate |
| J | 0010880 | biological_process | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum |
| J | 0010881 | biological_process | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion |
| J | 0016020 | cellular_component | membrane |
| J | 0016529 | cellular_component | sarcoplasmic reticulum |
| J | 0016853 | molecular_function | isomerase activity |
| J | 0019227 | biological_process | neuronal action potential propagation |
| J | 0019722 | biological_process | calcium-mediated signaling |
| J | 0019855 | molecular_function | calcium channel inhibitor activity |
| J | 0030018 | cellular_component | Z disc |
| J | 0030073 | biological_process | insulin secretion |
| J | 0033017 | cellular_component | sarcoplasmic reticulum membrane |
| J | 0034704 | cellular_component | calcium channel complex |
| J | 0035773 | biological_process | insulin secretion involved in cellular response to glucose stimulus |
| J | 0042026 | biological_process | protein refolding |
| J | 0042098 | biological_process | T cell proliferation |
| J | 0044325 | molecular_function | transmembrane transporter binding |
| J | 0050849 | biological_process | negative regulation of calcium-mediated signaling |
| J | 0051209 | biological_process | release of sequestered calcium ion into cytosol |
| J | 0051280 | biological_process | negative regulation of release of sequestered calcium ion into cytosol |
| J | 0051284 | biological_process | positive regulation of sequestering of calcium ion |
| J | 0051604 | biological_process | protein maturation |
| J | 0051775 | biological_process | response to redox state |
| J | 0061179 | biological_process | negative regulation of insulin secretion involved in cellular response to glucose stimulus |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 352 |
| Details | Domain: {"description":"PPIase FKBP-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00277","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |






