6PUA

The 2.0 A Crystal Structure of the Type B Chloramphenicol Acetyltransferase from Vibrio cholerae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0046677	biological_process	response to antibiotic
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
B	0046677	biological_process	response to antibiotic
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity
C	0046677	biological_process	response to antibiotic

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue MPD A 301

Chain	Residue
A	TRP183
A	SER187
A	ASN202
A	LYS206

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site_id	AC2
Number of Residues	2
Details	binding site for residue EDO A 302

Chain	Residue
A	HIS37
A	ASP41

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site_id	AC3
Number of Residues	3
Details	binding site for residue EDO A 303

Chain	Residue
A	HIS113
A	HIS131
A	HOH518

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site_id	AC4
Number of Residues	3
Details	binding site for residue EDO A 304

Chain	Residue
A	ASN2
A	TYR33
B	ASP41

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site_id	AC5
Number of Residues	2
Details	binding site for residue EDO A 305

Chain	Residue
A	GLN76
C	PHE8

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site_id	AC6
Number of Residues	1
Details	binding site for residue EDO A 306

Chain	Residue
A	PHE8

---

site_id	AC7
Number of Residues	4
Details	binding site for residue MPD A 307

Chain	Residue
A	TRP116
A	SER137
A	HOH448
B	MET124

---

site_id	AC8
Number of Residues	3
Details	binding site for residue CL A 308

Chain	Residue
A	ASN154
B	ASN154
C	ASN154

---

site_id	AC9
Number of Residues	3
Details	binding site for residue PO4 A 309

Chain	Residue
A	HIS47
A	TYR90
A	PHE103

---

site_id	AD1
Number of Residues	3
Details	binding site for residue EDO B 301

Chain	Residue
A	HOH517
B	ARG79
B	TRP82

---

site_id	AD2
Number of Residues	3
Details	binding site for residue EDO B 302

Chain	Residue
B	HIS113
B	ASN178
B	HOH477

---

site_id	AD3
Number of Residues	1
Details	binding site for residue EDO B 303

Chain	Residue
B	PHE8

---

site_id	AD4
Number of Residues	2
Details	binding site for residue PO4 B 304

Chain	Residue
B	PHE8
C	HIS47

---

site_id	AD5
Number of Residues	4
Details	binding site for residue MPD B 305

Chain	Residue
B	TRP116
B	SER137
B	HOH423
B	HOH488

---

site_id	AD6
Number of Residues	3
Details	binding site for residue PO4 B 306

Chain	Residue
A	PHE8
B	HIS47
B	TYR90

---

site_id	AD7
Number of Residues	6
Details	binding site for residue MPD B 307

Chain	Residue
B	TRP183
B	GLU186
B	SER187
B	SER190
B	ASN202
B	LYS206

---

site_id	AD8
Number of Residues	4
Details	binding site for residue PO4 C 301

Chain	Residue
C	HIS113
C	ASN178
C	HOH428
C	HOH461

---

site_id	AD9
Number of Residues	1
Details	binding site for residue PO4 C 302

Chain	Residue
C	SER187

---

site_id	AE1
Number of Residues	1
Details	binding site for residue EDO C 303

Chain	Residue
C	ASP41

---

site_id	AE2
Number of Residues	5
Details	binding site for residue MPD C 304

Chain	Residue
C	TRP116
C	GLY118
C	ALA136
C	SER137
C	HOH454

---

site_id	AE3
Number of Residues	6
Details	binding site for residue EDO C 305

Chain	Residue
B	SER193
B	SER194
C	ARG79
C	TRP82
C	ARG100
C	HOH485

---

site_id	AE4
Number of Residues	5
Details	binding site for residue PO4 C 306

Chain	Residue
C	GLU120
C	ARG138
C	HOH402
C	HOH411
C	HOH414

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Functional Information from PROSITE/UniProt

site_id	PS00101
Number of Residues	29
Details	HEXAPEP_TRANSFERASES Hexapeptide-repeat containing-transferases signature. IGteAmImpgVkIGhgAiIAsrSvVtkdV

Chain	Residue	Details
A	ILE117-VAL145

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