6PU0

Pigeon Cryptochrome4 bound to flavin adenine dinucleotide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003677	molecular_function	DNA binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0032922	biological_process	circadian regulation of gene expression
A	0043153	biological_process	entrainment of circadian clock by photoperiod
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0071949	molecular_function	FAD binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	26
Details	binding site for residue FAD A 501

Chain	Residue
A	THR246
A	TRP350
A	HIS353
A	ARG356
A	HIS357
A	PHE379
A	ASP385
A	ALA386
A	ASP387
A	ILE390
A	ASN391
A	THR247
A	ASN394
A	LEU398
A	GOL508
A	HOH665
A	HOH711
A	HOH730
A	HOH760
A	GLY248
A	LEU249
A	SER250
A	PHE253
A	SER254
A	GLN287
A	ARG291

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site_id	AC2
Number of Residues	6
Details	binding site for residue PGE A 502

Chain	Residue
A	ARG40
A	LEU158
A	GLY162
A	VAL282
A	GLN285
A	LEU289

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site_id	AC3
Number of Residues	3
Details	binding site for residue EDO A 503

Chain	Residue
A	SER245
A	HIS352
A	PEG505

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site_id	AC4
Number of Residues	4
Details	binding site for residue PEG A 504

Chain	Residue
A	GLY122
A	ILE410
A	HOH823
A	HOH881

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site_id	AC5
Number of Residues	5
Details	binding site for residue PEG A 505

Chain	Residue
A	ALA355
A	THR420
A	TYR426
A	EDO503
A	HOH681

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site_id	AC6
Number of Residues	4
Details	binding site for residue PEG A 506

Chain	Residue
A	MET46
A	ILE48
A	ARG52
A	LEU384

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site_id	AC7
Number of Residues	2
Details	binding site for residue PEG A 507

Chain	Residue
A	GLY309
A	GLN315

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site_id	AC8
Number of Residues	8
Details	binding site for residue GOL A 508

Chain	Residue
A	ARG86
A	GLU120
A	HIS353
A	HIS357
A	ASN394
A	TRP397
A	FAD501
A	HOH790

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