6PTZ

Crystal structure of pigeon Cryptochrome 4 mutant Y319D in complex with flavin adenine dinucleotide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003677	molecular_function	DNA binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0032922	biological_process	circadian regulation of gene expression
A	0043153	biological_process	entrainment of circadian clock by photoperiod
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0071949	molecular_function	FAD binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	31
Details	binding site for residue FAD A 501

Chain	Residue
A	THR246
A	PHE294
A	TRP350
A	HIS353
A	ARG356
A	HIS357
A	PHE379
A	LEU383
A	ASP385
A	ALA386
A	ASP387
A	THR247
A	ILE390
A	ASN391
A	ASN394
A	TRP395
A	LEU398
A	MG502
A	GOL510
A	HOH645
A	HOH710
A	HOH774
A	GLY248
A	HOH806
A	HOH851
A	LEU249
A	SER250
A	PHE253
A	SER254
A	GLN287
A	ARG291

---

site_id	AC2
Number of Residues	5
Details	binding site for residue MG A 502

Chain	Residue
A	THR246
A	FAD501
A	HOH851
A	HOH935
A	HOH978

---

site_id	AC3
Number of Residues	3
Details	binding site for residue PEG A 503

Chain	Residue
A	GLN273
A	PEG507
A	HOH858

---

site_id	AC4
Number of Residues	5
Details	binding site for residue PEG A 504

Chain	Residue
A	TRP337
A	THR420
A	TYR426
A	HOH800
A	HOH805

---

site_id	AC5
Number of Residues	4
Details	binding site for residue PEG A 505

Chain	Residue
A	ARG52
A	MET255
A	LEU384
A	HOH681

---

site_id	AC6
Number of Residues	2
Details	binding site for residue PEG A 506

Chain	Residue
A	LYS91
A	ASN93

---

site_id	AC7
Number of Residues	6
Details	binding site for residue PEG A 507

Chain	Residue
A	GLY309
A	ASN310
A	GLN315
A	MET468
A	PEG503
A	HOH635

---

site_id	AC8
Number of Residues	7
Details	binding site for residue PEG A 508

Chain	Residue
A	ALA119
A	GLU120
A	GLY122
A	ILE410
A	PHE411
A	HOH880
A	HOH961

---

site_id	AC9
Number of Residues	7
Details	binding site for residue PEG A 509

Chain	Residue
A	ARG40
A	LEU158
A	GLY162
A	PHE264
A	GLN285
A	LEU289
A	HOH637

---

site_id	AD1
Number of Residues	8
Details	binding site for residue GOL A 510

Chain	Residue
A	ARG86
A	GLU120
A	HIS353
A	HIS357
A	ASN394
A	TRP397
A	FAD501
A	HOH907

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