6PTD
PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C MUTANT H32L
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004436 | molecular_function | phosphatidylinositol diacylglycerol-lyase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| A | 0016042 | biological_process | lipid catabolic process |
| A | 0016829 | molecular_function | lyase activity |
Functional Information from PDB Data
| site_id | ACT |
| Number of Residues | 2 |
| Details | ACTIVE SITE. |
| Chain | Residue |
| A | LEU32 |
| A | HIS82 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor |
| Chain | Residue | Details |
| A | LEU32 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor |
| Chain | Residue | Details |
| A | HIS82 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 26 |
| Chain | Residue | Details |
| A | LEU32 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | ASP33 | electrostatic stabiliser, hydrogen bond acceptor |
| A | ARG69 | electrostatic stabiliser, hydrogen bond donor |
| A | HIS82 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | ASP274 | electrostatic stabiliser, hydrogen bond acceptor |
