Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | binding site for residue VRB A 601 |
| Chain | Residue |
| A | TYR463 |
| A | GLN509 |
| A | THR520 |
| A | CYS522 |
| A | HIS523 |
| A | GLN526 |
| A | LEU530 |
| A | ASN535 |
| A | ILE551 |
| A | HIS553 |
| A | EDO602 |
| A | ASP492 |
| A | HOH720 |
| A | HOH764 |
| A | HOH809 |
| B | HIS498 |
| A | PRO493 |
| A | CYS494 |
| A | PHE495 |
| A | HIS498 |
| A | TRP499 |
| A | TYR503 |
| A | ARG507 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 602 |
| Chain | Residue |
| A | GLN509 |
| A | THR511 |
| A | HIS523 |
| A | ASN535 |
| A | VRB601 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 603 |
| Chain | Residue |
| A | TYR469 |
| A | GLN545 |
| A | LEU546 |
| A | HOH730 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 604 |
| Chain | Residue |
| A | GLU581 |
| A | HIS584 |
| A | HOH711 |
| A | HOH728 |
| A | HOH737 |
| A | HOH794 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 605 |
| Chain | Residue |
| A | HOH765 |
| A | HOH796 |
| A | HOH842 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 606 |
| Chain | Residue |
| A | GLN505 |
| A | HOH790 |
| B | ARG507 |
| B | HOH762 |
| B | HOH847 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 607 |
| Chain | Residue |
| A | HOH708 |
| B | ALA502 |
| B | HOH819 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue CL A 608 |
| Chain | Residue |
| A | PHE495 |
| A | ARG496 |
| A | HIS498 |
| A | TRP499 |
| A | VAL500 |
| A | GLU501 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 609 |
| Chain | Residue |
| A | GLN560 |
| A | HOH789 |
| B | HOH817 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 601 |
| Chain | Residue |
| A | TRP561 |
| A | GLU563 |
| A | ILE566 |
| B | TYR469 |
| B | ARG496 |
| B | HOH711 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 603 |
| Chain | Residue |
| B | GLN509 |
| B | THR511 |
| B | HIS523 |
| B | ASN535 |
| B | VRB602 |
| B | HOH714 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 604 |
| Chain | Residue |
| A | GLN505 |
| B | ILE508 |
| B | GLN509 |
| B | ALA510 |
| B | HOH726 |
| B | HOH830 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue PEG B 605 |
| Chain | Residue |
| B | PHE465 |
| B | ASP466 |
| B | ASP467 |
| B | LEU546 |
| B | HOH744 |
| site_id | AD5 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 606 |
| Chain | Residue |
| A | ARG452 |
| A | ALA479 |
| A | GLU480 |
| A | HOH729 |
| B | TRP482 |
| B | SER556 |
| B | HOH712 |
| B | HOH724 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 607 |
| Chain | Residue |
| A | GLU480 |
| B | ARG533 |
| B | HOH724 |
| B | HOH760 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 608 |
| Chain | Residue |
| A | HOH715 |
| A | HOH831 |
| B | CL612 |
| B | HOH709 |
| B | HOH721 |
| B | HOH737 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue MG B 609 |
| Chain | Residue |
| B | ASP543 |
| B | GLU581 |
| B | HIS584 |
| B | HOH702 |
| B | HOH708 |
| B | HOH764 |
| B | HOH841 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 610 |
| Chain | Residue |
| A | HOH702 |
| A | HOH829 |
| B | SER435 |
| B | ASP439 |
| B | HOH701 |
| B | HOH723 |
| site_id | AE1 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 611 |
| Chain | Residue |
| B | THR512 |
| B | TRP561 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue CL B 612 |
| Chain | Residue |
| A | ASP567 |
| A | HOH715 |
| B | GLU501 |
| B | MG608 |
| B | HOH709 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 614 |
| Chain | Residue |
| B | SER477 |
| B | VAL478 |
| B | HOH820 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 615 |
| Chain | Residue |
| B | GLU476 |
| B | GLN484 |
| B | ARG486 |
| B | HOH818 |
| site_id | AE5 |
| Number of Residues | 28 |
| Details | binding site for Di-peptide VRB B 602 and CYS B 522 |
| Chain | Residue |
| A | ARG507 |
| B | TYR463 |
| B | ASP492 |
| B | PRO493 |
| B | CYS494 |
| B | PHE495 |
| B | HIS498 |
| B | TRP499 |
| B | TYR503 |
| B | ARG507 |
| B | GLN509 |
| B | THR520 |
| B | GLU521 |
| B | HIS523 |
| B | LEU524 |
| B | ASN525 |
| B | GLN526 |
| B | LEU527 |
| B | LEU530 |
| B | ASN535 |
| B | ILE551 |
| B | HIS553 |
| B | EDO603 |
| B | HOH729 |
| B | HOH735 |
| B | HOH769 |
| B | HOH787 |
| B | HOH803 |
| site_id | AE6 |
| Number of Residues | 25 |
| Details | binding site for Di-peptide VRB B 602 and CYS B 494 |
| Chain | Residue |
| A | ARG507 |
| B | TYR463 |
| B | ASP492 |
| B | PRO493 |
| B | PHE495 |
| B | ARG496 |
| B | GLU497 |
| B | HIS498 |
| B | TRP499 |
| B | TYR503 |
| B | ARG507 |
| B | GLN509 |
| B | THR520 |
| B | CYS522 |
| B | HIS523 |
| B | GLN526 |
| B | LEU527 |
| B | LEU530 |
| B | ASN535 |
| B | ILE551 |
| B | HIS553 |
| B | EDO603 |
| B | HOH729 |
| B | HOH735 |
| B | HOH769 |
