6POP
Crystal structure of DauA in complex with NADP+
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 30 |
| Details | binding site for residue NAP A 501 |
| Chain | Residue |
| A | PHE144 |
| A | ASP209 |
| A | LEU222 |
| A | ILE223 |
| A | GLY224 |
| A | SER225 |
| A | VAL228 |
| A | HIS231 |
| A | GLU246 |
| A | LEU247 |
| A | GLY248 |
| A | LEU145 |
| A | GLY249 |
| A | CYS280 |
| A | GLU378 |
| A | LEU406 |
| A | HIS443 |
| A | EDO504 |
| A | HOH609 |
| A | HOH617 |
| A | HOH669 |
| A | HOH678 |
| A | TRP147 |
| A | HOH681 |
| A | ASN148 |
| A | LYS171 |
| A | SER173 |
| A | SER174 |
| A | ASP204 |
| A | GLY208 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | ASN440 |
| A | LEU457 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | NAP501 |
| A | HOH607 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | ILE22 |
| A | PRO24 |
| A | MET323 |
| A | ASP324 |
| A | TYR358 |
| A | HOH622 |
| site_id | AC5 |
| Number of Residues | 34 |
| Details | binding site for residue NAP B 501 |
| Chain | Residue |
| B | PHE144 |
| B | LEU145 |
| B | ALA146 |
| B | TRP147 |
| B | ASN148 |
| B | LYS171 |
| B | SER173 |
| B | SER174 |
| B | ASP204 |
| B | GLY208 |
| B | ASP209 |
| B | LEU222 |
| B | ILE223 |
| B | GLY224 |
| B | SER225 |
| B | VAL228 |
| B | HIS231 |
| B | GLU246 |
| B | LEU247 |
| B | GLY248 |
| B | GLY249 |
| B | CYS280 |
| B | GLU378 |
| B | PHE380 |
| B | HIS443 |
| B | MG503 |
| B | HOH605 |
| B | HOH615 |
| B | HOH617 |
| B | HOH627 |
| B | HOH629 |
| B | HOH641 |
| B | HOH643 |
| B | HOH661 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 502 |
| Chain | Residue |
| B | LEU152 |
| B | TYR156 |
| B | TYR437 |
| B | HIS443 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 503 |
| Chain | Residue |
| B | NAP501 |
| B | HOH605 |
| B | HOH615 |
| B | HOH635 |
| B | HOH643 |
| B | HOH661 |
| site_id | AC8 |
| Number of Residues | 34 |
| Details | binding site for residue NAP C 501 |
| Chain | Residue |
| C | HIS231 |
| C | GLU246 |
| C | LEU247 |
| C | GLY248 |
| C | GLY249 |
| C | CYS280 |
| C | GLU378 |
| C | LEU406 |
| C | HIS443 |
| C | MG502 |
| C | HOH604 |
| C | HOH607 |
| C | HOH611 |
| C | HOH612 |
| C | HOH635 |
| C | HOH639 |
| C | HOH640 |
| C | HOH670 |
| C | HOH683 |
| C | PHE144 |
| C | LEU145 |
| C | TRP147 |
| C | ASN148 |
| C | LYS171 |
| C | SER173 |
| C | SER174 |
| C | ASP204 |
| C | GLY208 |
| C | ASP209 |
| C | LEU222 |
| C | ILE223 |
| C | GLY224 |
| C | SER225 |
| C | VAL228 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue MG C 502 |
| Chain | Residue |
| C | NAP501 |
| C | HOH604 |
| C | HOH639 |
| C | HOH670 |
| C | HOH683 |
| C | HOH699 |
| site_id | AD1 |
| Number of Residues | 32 |
| Details | binding site for residue NAP D 501 |
| Chain | Residue |
| D | PHE144 |
| D | LEU145 |
| D | TRP147 |
| D | ASN148 |
| D | LYS171 |
| D | SER173 |
| D | SER174 |
| D | ASP204 |
| D | GLY208 |
| D | ASP209 |
| D | LEU222 |
| D | ILE223 |
| D | GLY224 |
| D | SER225 |
| D | VAL228 |
| D | HIS231 |
| D | GLU246 |
| D | LEU247 |
| D | GLY248 |
| D | CYS280 |
| D | GLU378 |
| D | PHE380 |
| D | HIS443 |
| D | EDO504 |
| D | HOH604 |
| D | HOH605 |
| D | HOH611 |
| D | HOH620 |
| D | HOH623 |
| D | HOH633 |
| D | HOH665 |
| D | HOH666 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 502 |
| Chain | Residue |
| C | ILE122 |
| D | SER456 |
| D | LEU457 |
| D | LEU458 |
| D | HOH610 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 503 |
| Chain | Residue |
| D | TYR156 |
| D | TYR437 |
| D | HOH649 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 504 |
| Chain | Residue |
| D | SER225 |
| D | VAL228 |
| D | NAP501 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue EDO D 505 |
| Chain | Residue |
| D | THR226 |
| D | ALA404 |
| site_id | AD6 |
| Number of Residues | 29 |
| Details | binding site for residue NAP E 501 |
| Chain | Residue |
| E | LEU145 |
| E | ALA146 |
| E | TRP147 |
| E | ASN148 |
| E | LYS171 |
| E | SER173 |
| E | SER174 |
| E | ASP204 |
| E | GLY208 |
| E | ASP209 |
| E | LEU222 |
| E | ILE223 |
| E | GLY224 |
| E | SER225 |
| E | VAL228 |
| E | HIS231 |
| E | GLU246 |
| E | LEU247 |
| E | GLY248 |
| E | GLY249 |
| E | CYS280 |
| E | GLU378 |
| E | PHE380 |
| E | HIS443 |
| E | HOH605 |
| E | HOH625 |
| E | HOH632 |
| E | HOH636 |
| E | HOH639 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO E 502 |
| Chain | Residue |
| E | TYR156 |
| E | VAL281 |
| E | TYR437 |
| E | HIS443 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO E 503 |
| Chain | Residue |
| E | ARG63 |
| E | ILE114 |
| E | ARG135 |
| site_id | AD9 |
| Number of Residues | 30 |
| Details | binding site for residue NAP F 501 |
| Chain | Residue |
| F | PHE144 |
| F | LEU145 |
| F | ALA146 |
| F | TRP147 |
| F | ASN148 |
| F | LYS171 |
| F | SER173 |
| F | SER174 |
| F | ASP204 |
| F | GLY208 |
| F | ASP209 |
| F | LEU222 |
| F | ILE223 |
| F | GLY224 |
| F | SER225 |
| F | VAL228 |
| F | HIS231 |
| F | GLU246 |
| F | LEU247 |
| F | GLY248 |
| F | CYS280 |
| F | GLU378 |
| F | PHE380 |
| F | HIS443 |
| F | HOH615 |
| F | HOH633 |
| F | HOH639 |
| F | HOH643 |
| F | HOH653 |
| F | HOH672 |
| site_id | AE1 |
| Number of Residues | 2 |
| Details | binding site for residue EDO F 502 |
| Chain | Residue |
| F | TYR156 |
| F | HIS443 |
| site_id | AE2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO F 503 |
| Chain | Residue |
| F | THR226 |
| F | ASP403 |
Functional Information from PROSITE/UniProt
| site_id | PS00687 |
| Number of Residues | 8 |
| Details | ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. MELGGNAP |
| Chain | Residue | Details |
| A | MET245-PRO252 |
