6PO4
2.1 Angstrom Resolution Crystal Structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN) from Haemophilus influenzae PittII.
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0008782 | molecular_function | adenosylhomocysteine nucleosidase activity |
A | 0008930 | molecular_function | methylthioadenosine nucleosidase activity |
A | 0009116 | biological_process | nucleoside metabolic process |
A | 0009164 | biological_process | nucleoside catabolic process |
A | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
B | 0003824 | molecular_function | catalytic activity |
B | 0008782 | molecular_function | adenosylhomocysteine nucleosidase activity |
B | 0008930 | molecular_function | methylthioadenosine nucleosidase activity |
B | 0009116 | biological_process | nucleoside metabolic process |
B | 0009164 | biological_process | nucleoside catabolic process |
B | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
C | 0003824 | molecular_function | catalytic activity |
C | 0008782 | molecular_function | adenosylhomocysteine nucleosidase activity |
C | 0008930 | molecular_function | methylthioadenosine nucleosidase activity |
C | 0009116 | biological_process | nucleoside metabolic process |
C | 0009164 | biological_process | nucleoside catabolic process |
C | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
D | 0003824 | molecular_function | catalytic activity |
D | 0008782 | molecular_function | adenosylhomocysteine nucleosidase activity |
D | 0008930 | molecular_function | methylthioadenosine nucleosidase activity |
D | 0009116 | biological_process | nucleoside metabolic process |
D | 0009164 | biological_process | nucleoside catabolic process |
D | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
E | 0003824 | molecular_function | catalytic activity |
E | 0008782 | molecular_function | adenosylhomocysteine nucleosidase activity |
E | 0008930 | molecular_function | methylthioadenosine nucleosidase activity |
E | 0009116 | biological_process | nucleoside metabolic process |
E | 0009164 | biological_process | nucleoside catabolic process |
E | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
F | 0003824 | molecular_function | catalytic activity |
F | 0008782 | molecular_function | adenosylhomocysteine nucleosidase activity |
F | 0008930 | molecular_function | methylthioadenosine nucleosidase activity |
F | 0009116 | biological_process | nucleoside metabolic process |
F | 0009164 | biological_process | nucleoside catabolic process |
F | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 2 |
Details | binding site for residue HCS A 301 |
Chain | Residue |
A | PHE105 |
C | ASN39 |
site_id | AC2 |
Number of Residues | 12 |
Details | binding site for residue ADE A 302 |
Chain | Residue |
A | MET173 |
A | SER196 |
A | ASP197 |
A | GLY199 |
A | BO3303 |
A | SER76 |
A | ALA77 |
A | GLY78 |
A | SER150 |
A | PHE151 |
A | ILE152 |
A | GLU172 |
site_id | AC3 |
Number of Residues | 9 |
Details | binding site for residue BO3 A 303 |
Chain | Residue |
A | ALA8 |
A | GLU12 |
A | SER76 |
A | GLU172 |
A | MET173 |
A | GLU174 |
A | ARG193 |
A | ADE302 |
A | HOH413 |
site_id | AC4 |
Number of Residues | 10 |
Details | binding site for residue ADE B 301 |
Chain | Residue |
B | ALA77 |
B | GLY78 |
B | SER150 |
B | PHE151 |
B | ILE152 |
B | GLU172 |
B | SER196 |
B | ASP197 |
B | GLY199 |
B | BO3303 |
site_id | AC5 |
Number of Residues | 4 |
Details | binding site for residue HCS B 302 |
Chain | Residue |
B | PHE105 |
B | TYR107 |
E | GLU208 |
F | HCS302 |
site_id | AC6 |
Number of Residues | 8 |
Details | binding site for residue BO3 B 303 |
Chain | Residue |
B | GLU12 |
B | SER76 |
B | GLU172 |
B | MET173 |
B | GLU174 |
B | ARG193 |
B | ADE301 |
B | HOH407 |
site_id | AC7 |
Number of Residues | 11 |
Details | binding site for residue ADE C 301 |
Chain | Residue |
C | ALA77 |
C | GLY78 |
C | SER150 |
C | PHE151 |
C | ILE152 |
C | GLU172 |
C | MET173 |
C | SER196 |
C | ASP197 |
C | GLY199 |
C | BO3304 |
site_id | AC8 |
Number of Residues | 1 |
Details | binding site for residue HCS C 302 |
Chain | Residue |
C | PHE105 |
site_id | AC9 |
Number of Residues | 2 |
Details | binding site for residue HCS C 303 |
Chain | Residue |
C | ILE50 |
D | TYR107 |
site_id | AD1 |
Number of Residues | 8 |
Details | binding site for residue BO3 C 304 |
Chain | Residue |
C | GLU12 |
C | SER76 |
C | GLU172 |
C | MET173 |
C | GLU174 |
C | ARG193 |
C | ADE301 |
C | HOH411 |
site_id | AD2 |
Number of Residues | 10 |
Details | binding site for residue ADE D 301 |
Chain | Residue |
D | ALA77 |
D | GLY78 |
D | SER150 |
D | PHE151 |
D | ILE152 |
D | GLU172 |
D | SER196 |
D | ASP197 |
D | GLY199 |
D | BO3302 |
site_id | AD3 |
Number of Residues | 8 |
Details | binding site for residue BO3 D 302 |
Chain | Residue |
D | GLU12 |
D | SER76 |
D | GLU172 |
D | MET173 |
D | GLU174 |
D | ARG193 |
D | ADE301 |
D | HOH411 |
site_id | AD4 |
Number of Residues | 11 |
Details | binding site for residue ADE E 301 |
Chain | Residue |
E | ALA77 |
E | GLY78 |
E | SER150 |
E | PHE151 |
E | ILE152 |
E | GLU172 |
E | MET173 |
E | SER196 |
E | ASP197 |
E | GLY199 |
E | BO3303 |
site_id | AD5 |
Number of Residues | 2 |
Details | binding site for residue HCS E 302 |
Chain | Residue |
A | ASN39 |
E | PHE105 |
site_id | AD6 |
Number of Residues | 8 |
Details | binding site for residue BO3 E 303 |
Chain | Residue |
E | SER76 |
E | GLU172 |
E | MET173 |
E | GLU174 |
E | ARG193 |
E | ADE301 |
E | HOH409 |
E | GLU12 |
site_id | AD7 |
Number of Residues | 12 |
Details | binding site for residue ADE F 301 |
Chain | Residue |
F | SER76 |
F | ALA77 |
F | GLY78 |
F | SER150 |
F | PHE151 |
F | ILE152 |
F | GLU172 |
F | MET173 |
F | SER196 |
F | ASP197 |
F | GLY199 |
F | BO3303 |
site_id | AD8 |
Number of Residues | 5 |
Details | binding site for residue HCS F 302 |
Chain | Residue |
A | GLU208 |
B | HCS302 |
E | ILE50 |
F | TYR107 |
F | HOH461 |
site_id | AD9 |
Number of Residues | 9 |
Details | binding site for residue BO3 F 303 |
Chain | Residue |
F | ALA8 |
F | GLU12 |
F | SER76 |
F | GLU172 |
F | MET173 |
F | GLU174 |
F | ARG193 |
F | ADE301 |
F | HOH406 |