Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004517 | molecular_function | nitric-oxide synthase activity |
| A | 0006809 | biological_process | nitric oxide biosynthetic process |
| B | 0004517 | molecular_function | nitric-oxide synthase activity |
| B | 0006809 | biological_process | nitric oxide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue HEM A 801 |
| Chain | Residue |
| A | TRP414 |
| A | PHE709 |
| A | TYR711 |
| A | OSG802 |
| A | HOH901 |
| A | HOH908 |
| A | HOH969 |
| A | HOH1023 |
| A | HOH1056 |
| B | HOH922 |
| A | ARG419 |
| A | CYS420 |
| A | PHE589 |
| A | SER590 |
| A | TRP592 |
| A | MET594 |
| A | GLU597 |
| A | TRP683 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue OSG A 802 |
| Chain | Residue |
| A | MET341 |
| A | VAL572 |
| A | ASN574 |
| A | PHE589 |
| A | GLY591 |
| A | TRP592 |
| A | TYR593 |
| A | GLU597 |
| A | TYR711 |
| A | HEM801 |
| A | HOH990 |
| B | OSG801 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue OSG A 803 |
| Chain | Residue |
| A | TRP311 |
| A | TRP681 |
| A | PHE696 |
| B | SER339 |
| B | MET341 |
| B | VAL682 |
| B | TRP683 |
| B | OSG804 |
| B | HOH911 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | binding site for residue OSG B 801 |
| Chain | Residue |
| A | SER339 |
| A | MET341 |
| A | VAL682 |
| A | TRP683 |
| A | OSG802 |
| B | TRP311 |
| B | TRP681 |
| B | PHE696 |
| B | HOH922 |
| B | HOH1047 |
| B | HOH1083 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 802 |
| Chain | Residue |
| A | CYS331 |
| A | CYS336 |
| B | CYS331 |
| B | CYS336 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | binding site for residue HEM B 803 |
| Chain | Residue |
| B | TRP414 |
| B | ARG419 |
| B | CYS420 |
| B | SER462 |
| B | PHE589 |
| B | SER590 |
| B | TRP592 |
| B | GLU597 |
| B | TRP683 |
| B | PHE709 |
| B | TYR711 |
| B | OSG804 |
| B | HOH911 |
| B | HOH929 |
| B | HOH1005 |
| B | HOH1066 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue OSG B 804 |
| Chain | Residue |
| A | OSG803 |
| B | VAL572 |
| B | TRP592 |
| B | TYR593 |
| B | GLU597 |
| B | TRP683 |
| B | HEM803 |
| B | HOH1081 |
| B | HOH1087 |
Functional Information from PROSITE/UniProt
| site_id | PS60001 |
| Number of Residues | 8 |
| Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
| Chain | Residue | Details |
| A | ARG419-TRP426 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25286850","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4D1N","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"25286850","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4D1N","evidenceCode":"ECO:0007744"}]} |
