6PMP
Crystal structure of a fragment of rat phospholipase Cepsilon EF3-RA1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004435 | molecular_function | phosphatidylinositol-4,5-bisphosphate phospholipase C activity |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| A | 0035556 | biological_process | intracellular signal transduction |
| B | 0004435 | molecular_function | phosphatidylinositol-4,5-bisphosphate phospholipase C activity |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0007165 | biological_process | signal transduction |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0035556 | biological_process | intracellular signal transduction |
| C | 0004435 | molecular_function | phosphatidylinositol-4,5-bisphosphate phospholipase C activity |
| C | 0006629 | biological_process | lipid metabolic process |
| C | 0007165 | biological_process | signal transduction |
| C | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| C | 0035556 | biological_process | intracellular signal transduction |
| D | 0004435 | molecular_function | phosphatidylinositol-4,5-bisphosphate phospholipase C activity |
| D | 0006629 | biological_process | lipid metabolic process |
| D | 0007165 | biological_process | signal transduction |
| D | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| D | 0035556 | biological_process | intracellular signal transduction |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue CA A 2100 |
| Chain | Residue |
| A | ASN1389 |
| A | ASP1420 |
| A | GLU1467 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue CA B 2100 |
| Chain | Residue |
| B | ASN1389 |
| B | GLU1418 |
| B | ASP1420 |
| B | GLU1467 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CA C 2100 |
| Chain | Residue |
| C | ASP1420 |
| C | GLU1467 |
| C | ASN1389 |
| C | GLU1418 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue CA D 2100 |
| Chain | Residue |
| D | ASN1389 |
| D | GLU1418 |
| D | ASP1420 |
| D | GLU1467 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 148 |
| Details | Domain: {"description":"PI-PLC X-box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00270","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 500 |
| Details | Domain: {"description":"C2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00041","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00270","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
