6PJW
Adenylate kinase from Methanococcus igneus - AMP bound form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004017 | molecular_function | AMP kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0046940 | biological_process | nucleoside monophosphate phosphorylation |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004017 | molecular_function | AMP kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0046940 | biological_process | nucleoside monophosphate phosphorylation |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004017 | molecular_function | AMP kinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0016301 | molecular_function | kinase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0046940 | biological_process | nucleoside monophosphate phosphorylation |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004017 | molecular_function | AMP kinase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0016301 | molecular_function | kinase activity |
| D | 0016740 | molecular_function | transferase activity |
| D | 0046940 | biological_process | nucleoside monophosphate phosphorylation |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0004017 | molecular_function | AMP kinase activity |
| E | 0005524 | molecular_function | ATP binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0016301 | molecular_function | kinase activity |
| E | 0016740 | molecular_function | transferase activity |
| E | 0046940 | biological_process | nucleoside monophosphate phosphorylation |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0004017 | molecular_function | AMP kinase activity |
| F | 0005524 | molecular_function | ATP binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0016301 | molecular_function | kinase activity |
| F | 0016740 | molecular_function | transferase activity |
| F | 0046940 | biological_process | nucleoside monophosphate phosphorylation |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0004017 | molecular_function | AMP kinase activity |
| G | 0005524 | molecular_function | ATP binding |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0016301 | molecular_function | kinase activity |
| G | 0016740 | molecular_function | transferase activity |
| G | 0046940 | biological_process | nucleoside monophosphate phosphorylation |
| H | 0000166 | molecular_function | nucleotide binding |
| H | 0004017 | molecular_function | AMP kinase activity |
| H | 0005524 | molecular_function | ATP binding |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0016301 | molecular_function | kinase activity |
| H | 0016740 | molecular_function | transferase activity |
| H | 0046940 | biological_process | nucleoside monophosphate phosphorylation |
| I | 0000166 | molecular_function | nucleotide binding |
| I | 0004017 | molecular_function | AMP kinase activity |
| I | 0005524 | molecular_function | ATP binding |
| I | 0005737 | cellular_component | cytoplasm |
| I | 0016301 | molecular_function | kinase activity |
| I | 0016740 | molecular_function | transferase activity |
| I | 0046940 | biological_process | nucleoside monophosphate phosphorylation |
| J | 0000166 | molecular_function | nucleotide binding |
| J | 0004017 | molecular_function | AMP kinase activity |
| J | 0005524 | molecular_function | ATP binding |
| J | 0005737 | cellular_component | cytoplasm |
| J | 0016301 | molecular_function | kinase activity |
| J | 0016740 | molecular_function | transferase activity |
| J | 0046940 | biological_process | nucleoside monophosphate phosphorylation |
| K | 0000166 | molecular_function | nucleotide binding |
| K | 0004017 | molecular_function | AMP kinase activity |
| K | 0005524 | molecular_function | ATP binding |
| K | 0005737 | cellular_component | cytoplasm |
| K | 0016301 | molecular_function | kinase activity |
| K | 0016740 | molecular_function | transferase activity |
| K | 0046940 | biological_process | nucleoside monophosphate phosphorylation |
| L | 0000166 | molecular_function | nucleotide binding |
| L | 0004017 | molecular_function | AMP kinase activity |
| L | 0005524 | molecular_function | ATP binding |
| L | 0005737 | cellular_component | cytoplasm |
| L | 0016301 | molecular_function | kinase activity |
| L | 0016740 | molecular_function | transferase activity |
| L | 0046940 | biological_process | nucleoside monophosphate phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue AMP A 301 |
| Chain | Residue |
| A | ASN38 |
| A | HIS92 |
| A | VAL95 |
| A | GLY104 |
| A | ARG138 |
| A | HOH402 |
| A | HOH406 |
| A | HOH408 |
| A | HOH412 |
| A | PHE39 |
| A | GLY40 |
| A | MET43 |
| A | ARG56 |
| A | MET59 |
| A | ARG60 |
| A | GLN71 |
| A | THR91 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue AMP A 302 |
| Chain | Residue |
| A | GLY13 |
| A | GLY15 |
| A | THR18 |
| A | ARG131 |
| A | ASP135 |
| A | ASN175 |
| A | ARG176 |
| A | ASP177 |
| A | GLY178 |
| A | LEU180 |
| A | HOH407 |
| A | HOH410 |
| H | THR137 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 303 |
| Chain | Residue |
| A | THR17 |
| A | ARG140 |
| A | HOH402 |
| A | HOH407 |
| A | HOH408 |
| A | HOH410 |
| A | HOH412 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | binding site for residue AMP B 301 |
| Chain | Residue |
| B | ASN38 |
| B | PHE39 |
| B | GLY40 |
| B | MET43 |
| B | ARG56 |
| B | MET59 |
| B | ARG60 |
| B | GLN71 |
| B | THR91 |
| B | HIS92 |
| B | VAL95 |
| B | GLY104 |
| B | ARG138 |
| B | HOH411 |
| B | HOH413 |
| B | HOH414 |
| B | HOH417 |
| B | HOH419 |
| B | HOH421 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | binding site for residue AMP B 302 |
| Chain | Residue |
| B | GLY13 |
| B | GLY15 |
| B | THR17 |
| B | THR18 |
| B | ARG131 |
| B | ASN175 |
| B | ARG176 |
| B | ASP177 |
| B | GLY178 |
| B | LEU180 |
| B | HOH401 |
| B | HOH404 |
| B | HOH405 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 303 |
| Chain | Residue |
| B | THR17 |
| B | HOH404 |
| B | HOH405 |
| B | HOH413 |
| B | HOH417 |
| B | HOH421 |
| site_id | AC7 |
| Number of Residues | 16 |
| Details | binding site for residue AMP C 301 |
| Chain | Residue |
| C | ASN38 |
| C | GLY40 |
| C | MET43 |
| C | ARG56 |
| C | MET59 |
| C | ARG60 |
| C | GLN71 |
| C | THR91 |
| C | HIS92 |
| C | GLY104 |
| C | ARG138 |
| C | HOH403 |
| C | HOH406 |
| C | HOH408 |
| C | HOH410 |
| C | HOH414 |
| site_id | AC8 |
| Number of Residues | 15 |
| Details | binding site for residue AMP C 302 |
| Chain | Residue |
| C | ASN175 |
| C | ARG176 |
| C | ASP177 |
| C | GLY178 |
| C | LEU180 |
| C | HOH413 |
| C | HOH419 |
| C | GLY13 |
| C | VAL14 |
| C | GLY15 |
| C | THR17 |
| C | THR18 |
| C | ARG131 |
| C | ASP135 |
| C | ARG140 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue MG C 303 |
| Chain | Residue |
| C | THR17 |
| C | HOH406 |
| C | HOH408 |
| C | HOH413 |
| C | HOH414 |
| C | HOH419 |
| site_id | AD1 |
| Number of Residues | 18 |
| Details | binding site for residue AMP D 301 |
| Chain | Residue |
| D | ASN38 |
| D | PHE39 |
| D | GLY40 |
| D | MET43 |
| D | ARG56 |
| D | MET59 |
| D | ARG60 |
| D | GLN71 |
| D | THR91 |
| D | HIS92 |
| D | VAL95 |
| D | GLY104 |
| D | ARG138 |
| D | HOH408 |
| D | HOH411 |
| D | HOH413 |
| D | HOH414 |
| D | HOH416 |
| site_id | AD2 |
| Number of Residues | 12 |
| Details | binding site for residue AMP D 302 |
| Chain | Residue |
| D | GLY13 |
| D | GLY15 |
| D | THR18 |
| D | ARG131 |
| D | ASP135 |
| D | ASN175 |
| D | ARG176 |
| D | ASP177 |
| D | GLY178 |
| D | LEU180 |
| D | HOH404 |
| D | HOH415 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue MG D 303 |
| Chain | Residue |
| D | THR17 |
| D | HOH404 |
| D | HOH411 |
| D | HOH414 |
| D | HOH415 |
| D | HOH416 |
| site_id | AD4 |
| Number of Residues | 17 |
| Details | binding site for residue AMP E 301 |
| Chain | Residue |
| E | ASN38 |
| E | GLY40 |
| E | MET43 |
| E | ARG56 |
| E | MET59 |
| E | ARG60 |
| E | GLN71 |
| E | THR91 |
| E | HIS92 |
| E | VAL95 |
| E | GLY104 |
| E | ARG138 |
| E | HOH404 |
| E | HOH406 |
| E | HOH409 |
| E | HOH412 |
| E | HOH415 |
| site_id | AD5 |
| Number of Residues | 11 |
| Details | binding site for residue AMP E 302 |
| Chain | Residue |
| E | GLY13 |
| E | GLY15 |
| E | THR17 |
| E | THR18 |
| E | ARG131 |
| E | ASN175 |
| E | ARG176 |
| E | ASP177 |
| E | LEU180 |
| E | HOH402 |
| E | HOH417 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue MG E 303 |
| Chain | Residue |
| E | THR17 |
| E | HOH402 |
| E | HOH406 |
| E | HOH409 |
| E | HOH412 |
| E | HOH417 |
| site_id | AD7 |
| Number of Residues | 14 |
| Details | binding site for residue AMP F 301 |
| Chain | Residue |
| F | ASN38 |
| F | PHE39 |
| F | GLY40 |
| F | MET43 |
| F | ARG56 |
| F | MET59 |
| F | ARG60 |
| F | GLN71 |
| F | THR91 |
| F | HIS92 |
| F | GLY104 |
| F | ARG138 |
| F | HOH402 |
| F | HOH413 |
| site_id | AD8 |
| Number of Residues | 13 |
| Details | binding site for residue AMP F 302 |
| Chain | Residue |
| F | GLY13 |
| F | GLY15 |
| F | THR17 |
| F | THR18 |
| F | ARG131 |
| F | ARG140 |
| F | ASN175 |
| F | ARG176 |
| F | ASP177 |
| F | GLY178 |
| F | LEU180 |
| F | HOH408 |
| F | HOH416 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue MG F 303 |
| Chain | Residue |
| F | THR17 |
| F | HOH402 |
| F | HOH408 |
| F | HOH410 |
| F | HOH413 |
| F | HOH416 |
| site_id | AE1 |
| Number of Residues | 16 |
| Details | binding site for residue AMP G 301 |
| Chain | Residue |
| G | ASN38 |
| G | PHE39 |
| G | GLY40 |
| G | MET43 |
| G | ARG56 |
| G | MET59 |
| G | ARG60 |
| G | GLN71 |
| G | THR91 |
| G | HIS92 |
| G | VAL95 |
| G | GLY104 |
| G | ARG138 |
| G | HOH404 |
| G | HOH405 |
| G | HOH408 |
| site_id | AE2 |
| Number of Residues | 13 |
| Details | binding site for residue AMP G 302 |
| Chain | Residue |
| G | GLY13 |
| G | GLY15 |
| G | THR17 |
| G | THR18 |
| G | ARG131 |
| G | ASN175 |
| G | ARG176 |
| G | ASP177 |
| G | GLY178 |
| G | LEU180 |
| G | HOH401 |
| G | HOH402 |
| G | HOH409 |
| site_id | AE3 |
| Number of Residues | 6 |
| Details | binding site for residue MG G 303 |
| Chain | Residue |
| G | THR17 |
| G | HOH402 |
| G | HOH404 |
| G | HOH405 |
| G | HOH408 |
| G | HOH409 |
| site_id | AE4 |
| Number of Residues | 18 |
| Details | binding site for residue AMP H 301 |
| Chain | Residue |
| H | ASN38 |
| H | PHE39 |
| H | GLY40 |
| H | MET43 |
| H | ARG56 |
| H | MET59 |
| H | ARG60 |
| H | GLN71 |
| H | THR91 |
| H | HIS92 |
| H | VAL95 |
| H | GLY104 |
| H | ARG138 |
| H | HOH403 |
| H | HOH404 |
| H | HOH405 |
| H | HOH410 |
| H | HOH412 |
| site_id | AE5 |
| Number of Residues | 16 |
| Details | binding site for residue AMP H 302 |
| Chain | Residue |
| A | GLU25 |
| H | GLY13 |
| H | GLY15 |
| H | THR17 |
| H | THR18 |
| H | ARG131 |
| H | ASP135 |
| H | ARG140 |
| H | ASN175 |
| H | ARG176 |
| H | ASP177 |
| H | GLY178 |
| H | LEU180 |
| H | MG303 |
| H | HOH402 |
| H | HOH406 |
| site_id | AE6 |
| Number of Residues | 7 |
| Details | binding site for residue MG H 303 |
| Chain | Residue |
| H | THR17 |
| H | AMP302 |
| H | HOH402 |
| H | HOH403 |
| H | HOH406 |
| H | HOH410 |
| H | HOH412 |
| site_id | AE7 |
| Number of Residues | 16 |
| Details | binding site for residue AMP I 301 |
| Chain | Residue |
| I | ASN38 |
| I | PHE39 |
| I | GLY40 |
| I | MET43 |
| I | ARG56 |
| I | MET59 |
| I | ARG60 |
| I | GLN71 |
| I | THR91 |
| I | HIS92 |
| I | VAL95 |
| I | GLY104 |
| I | ARG138 |
| I | HOH405 |
| I | HOH407 |
| I | HOH409 |
| site_id | AE8 |
| Number of Residues | 12 |
| Details | binding site for residue AMP I 302 |
| Chain | Residue |
| I | GLY13 |
| I | GLY15 |
| I | THR17 |
| I | THR18 |
| I | ARG131 |
| I | ASN175 |
| I | ARG176 |
| I | ASP177 |
| I | LEU180 |
| I | HOH401 |
| I | HOH402 |
| I | HOH408 |
| site_id | AE9 |
| Number of Residues | 7 |
| Details | binding site for residue MG I 303 |
| Chain | Residue |
| I | THR17 |
| I | HOH401 |
| I | HOH402 |
| I | HOH405 |
| I | HOH407 |
| I | HOH408 |
| I | HOH409 |
| site_id | AF1 |
| Number of Residues | 17 |
| Details | binding site for residue AMP J 301 |
| Chain | Residue |
| J | ASN38 |
| J | PHE39 |
| J | GLY40 |
| J | MET43 |
| J | ARG56 |
| J | MET59 |
| J | ARG60 |
| J | GLN71 |
| J | THR91 |
| J | HIS92 |
| J | GLY104 |
| J | ARG138 |
| J | HOH407 |
| J | HOH409 |
| J | HOH410 |
| J | HOH411 |
| J | HOH415 |
| site_id | AF2 |
| Number of Residues | 14 |
| Details | binding site for residue AMP J 302 |
| Chain | Residue |
| D | GLU25 |
| D | LYS28 |
| D | GLU29 |
| J | GLY13 |
| J | GLY15 |
| J | THR18 |
| J | ARG131 |
| J | ASN175 |
| J | ARG176 |
| J | ASP177 |
| J | GLY178 |
| J | LEU180 |
| J | HOH404 |
| J | HOH413 |
| site_id | AF3 |
| Number of Residues | 6 |
| Details | binding site for residue MG J 303 |
| Chain | Residue |
| J | THR17 |
| J | HOH404 |
| J | HOH409 |
| J | HOH410 |
| J | HOH413 |
| J | HOH415 |
| site_id | AF4 |
| Number of Residues | 15 |
| Details | binding site for residue AMP K 301 |
| Chain | Residue |
| K | ASN38 |
| K | PHE39 |
| K | GLY40 |
| K | MET43 |
| K | ARG56 |
| K | MET59 |
| K | ARG60 |
| K | GLN71 |
| K | THR91 |
| K | HIS92 |
| K | GLY104 |
| K | ARG138 |
| K | HOH403 |
| K | HOH404 |
| K | HOH410 |
| site_id | AF5 |
| Number of Residues | 10 |
| Details | binding site for residue AMP K 302 |
| Chain | Residue |
| K | GLY13 |
| K | GLY15 |
| K | THR18 |
| K | ARG131 |
| K | ASN175 |
| K | ARG176 |
| K | ASP177 |
| K | GLY178 |
| K | LEU180 |
| K | HOH401 |
| site_id | AF6 |
| Number of Residues | 6 |
| Details | binding site for residue MG K 303 |
| Chain | Residue |
| K | THR17 |
| K | HOH401 |
| K | HOH403 |
| K | HOH404 |
| K | HOH409 |
| K | HOH410 |
| site_id | AF7 |
| Number of Residues | 17 |
| Details | binding site for residue AMP L 301 |
| Chain | Residue |
| L | ASN38 |
| L | PHE39 |
| L | GLY40 |
| L | MET43 |
| L | ARG56 |
| L | MET59 |
| L | ARG60 |
| L | GLN71 |
| L | THR91 |
| L | HIS92 |
| L | VAL95 |
| L | GLY104 |
| L | ARG138 |
| L | HOH402 |
| L | HOH409 |
| L | HOH414 |
| L | HOH419 |
| site_id | AF8 |
| Number of Residues | 10 |
| Details | binding site for residue AMP L 302 |
| Chain | Residue |
| L | GLY15 |
| L | THR17 |
| L | THR18 |
| L | ARG131 |
| L | ASN175 |
| L | ARG176 |
| L | LEU180 |
| L | HOH404 |
| L | HOH407 |
| L | HOH408 |
| site_id | AF9 |
| Number of Residues | 6 |
| Details | binding site for residue MG L 303 |
| Chain | Residue |
| L | THR17 |
| L | HOH404 |
| L | HOH407 |
| L | HOH409 |
| L | HOH414 |
| L | HOH419 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 96 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
