6PIK

Tetrameric cryo-EM ArnA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0009058	biological_process	biosynthetic process
B	0003824	molecular_function	catalytic activity
B	0009058	biological_process	biosynthetic process
C	0003824	molecular_function	catalytic activity
C	0009058	biological_process	biosynthetic process
D	0003824	molecular_function	catalytic activity
D	0009058	biological_process	biosynthetic process
E	0016831	molecular_function	carboxy-lyase activity
F	0016831	molecular_function	carboxy-lyase activity
G	0016831	molecular_function	carboxy-lyase activity
H	0016831	molecular_function	carboxy-lyase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton acceptor; for decarboxylase activity

Chain	Residue	Details
E	GLU434
F	GLU434
G	GLU434
H	GLU434

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site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: Proton donor; for decarboxylase activity

Chain	Residue	Details
E	ARG619
D	HIS86
D	ARG114
D	VAL136
F	ARG619
G	ARG619
H	ARG619
B	ARG114
B	VAL136
C	HIS86
C	ARG114
C	VAL136

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site_id	SWS_FT_FI3
Number of Residues	36
Details	BINDING:

Chain	Residue	Details
E	ASP347
F	ASP347
F	ASP368
F	ALA393
F	TYR398
F	THR432
F	ARG460
F	ASN492
F	LYS526
F	TYR613
G	ASP347
E	ASP368
G	ASP368
G	ALA393
G	TYR398
G	THR432
G	ARG460
G	ASN492
G	LYS526
G	TYR613
H	ASP347
H	ASP368
E	ALA393
H	ALA393
H	TYR398
H	THR432
H	ARG460
H	ASN492
H	LYS526
H	TYR613
E	TYR398
E	THR432
E	ARG460
E	ASN492
E	LYS526
E	TYR613

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site_id	SWS_FT_FI4
Number of Residues	4
Details	SITE: Raises pKa of active site His

Chain	Residue	Details
A	ASP140
B	ASP140
C	ASP140
D	ASP140

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