6PHE

Crystal structure of Methylglyoxal synthase from Elizabethkingia anophelis NUHP1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005829	cellular_component	cytosol
A	0008929	molecular_function	methylglyoxal synthase activity
A	0016829	molecular_function	lyase activity
A	0019242	biological_process	methylglyoxal biosynthetic process
B	0005829	cellular_component	cytosol
B	0008929	molecular_function	methylglyoxal synthase activity
B	0016829	molecular_function	lyase activity
B	0019242	biological_process	methylglyoxal biosynthetic process
C	0005829	cellular_component	cytosol
C	0008929	molecular_function	methylglyoxal synthase activity
C	0016829	molecular_function	lyase activity
C	0019242	biological_process	methylglyoxal biosynthetic process
D	0005829	cellular_component	cytosol
D	0008929	molecular_function	methylglyoxal synthase activity
D	0016829	molecular_function	lyase activity
D	0019242	biological_process	methylglyoxal biosynthetic process
E	0005829	cellular_component	cytosol
E	0008929	molecular_function	methylglyoxal synthase activity
E	0016829	molecular_function	lyase activity
E	0019242	biological_process	methylglyoxal biosynthetic process
F	0005829	cellular_component	cytosol
F	0008929	molecular_function	methylglyoxal synthase activity
F	0016829	molecular_function	lyase activity
F	0019242	biological_process	methylglyoxal biosynthetic process
G	0005829	cellular_component	cytosol
G	0008929	molecular_function	methylglyoxal synthase activity
G	0016829	molecular_function	lyase activity
G	0019242	biological_process	methylglyoxal biosynthetic process
H	0005829	cellular_component	cytosol
H	0008929	molecular_function	methylglyoxal synthase activity
H	0016829	molecular_function	lyase activity
H	0019242	biological_process	methylglyoxal biosynthetic process
I	0005829	cellular_component	cytosol
I	0008929	molecular_function	methylglyoxal synthase activity
I	0016829	molecular_function	lyase activity
I	0019242	biological_process	methylglyoxal biosynthetic process
J	0005829	cellular_component	cytosol
J	0008929	molecular_function	methylglyoxal synthase activity
J	0016829	molecular_function	lyase activity
J	0019242	biological_process	methylglyoxal biosynthetic process
K	0005829	cellular_component	cytosol
K	0008929	molecular_function	methylglyoxal synthase activity
K	0016829	molecular_function	lyase activity
K	0019242	biological_process	methylglyoxal biosynthetic process
L	0005829	cellular_component	cytosol
L	0008929	molecular_function	methylglyoxal synthase activity
L	0016829	molecular_function	lyase activity
L	0019242	biological_process	methylglyoxal biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue PO4 A 200

Chain	Residue
A	LYS22
A	THR44
A	THR46
A	THR47
A	SER64
A	GLY65
A	HOH308
A	HOH346
F	ARG148

---

site_id	AC2
Number of Residues	9
Details	binding site for residue PO4 B 200

Chain	Residue
B	LYS22
B	THR44
B	THR46
B	THR47
B	SER64
B	GLY65
B	HOH308
B	HOH327
C	ARG148

---

site_id	AC3
Number of Residues	9
Details	binding site for residue PO4 C 200

Chain	Residue
B	ARG148
C	LYS22
C	THR44
C	THR46
C	THR47
C	SER64
C	GLY65
C	HOH307
C	HOH335

---

site_id	AC4
Number of Residues	5
Details	binding site for residue MPD C 201

Chain	Residue
C	GLU52
C	GLY56
C	GLU58
H	THR37
H	HOH316

---

site_id	AC5
Number of Residues	9
Details	binding site for residue PO4 D 200

Chain	Residue
D	LYS22
D	THR44
D	THR46
D	THR47
D	SER64
D	GLY65
D	HOH307
D	HOH331
E	ARG148

---

site_id	AC6
Number of Residues	9
Details	binding site for residue PO4 E 201

Chain	Residue
D	ARG148
E	LYS22
E	THR44
E	THR46
E	THR47
E	SER64
E	GLY65
E	HOH309
E	HOH323

---

site_id	AC7
Number of Residues	10
Details	binding site for residue MPD E 202

Chain	Residue
E	PHE130
E	GLU134
E	TYR135
E	GLN136
E	HOH346
E	HOH356
L	PHE130
L	GLU134
L	TYR135
L	GLN136

---

site_id	AC8
Number of Residues	9
Details	binding site for residue PO4 F 200

Chain	Residue
A	ARG148
F	LYS22
F	THR44
F	THR46
F	THR47
F	SER64
F	GLY65
F	HOH303
F	HOH340

---

site_id	AC9
Number of Residues	9
Details	binding site for residue PO4 G 200

Chain	Residue
G	LYS22
G	THR44
G	THR46
G	THR47
G	SER64
G	GLY65
G	HOH310
G	HOH325
L	ARG148

---

site_id	AD1
Number of Residues	9
Details	binding site for residue PO4 H 200

Chain	Residue
H	LYS22
H	THR44
H	THR46
H	THR47
H	SER64
H	GLY65
H	HOH310
I	ARG148
I	HOH346

---

site_id	AD2
Number of Residues	9
Details	binding site for residue PO4 I 200

Chain	Residue
H	ARG148
I	LYS22
I	THR44
I	THR46
I	THR47
I	SER64
I	GLY65
I	HOH302
I	HOH312

---

site_id	AD3
Number of Residues	9
Details	binding site for residue PO4 J 200

Chain	Residue
J	THR47
J	SER64
J	GLY65
J	HOH302
J	HOH309
K	ARG148
J	LYS22
J	THR44
J	THR46

---

site_id	AD4
Number of Residues	9
Details	binding site for residue PO4 K 200

Chain	Residue
J	ARG148
K	LYS22
K	THR44
K	THR46
K	THR47
K	SER64
K	GLY65
K	HOH313
K	HOH319

---

site_id	AD5
Number of Residues	9
Details	binding site for residue PO4 L 200

Chain	Residue
G	ARG148
L	LYS22
L	THR44
L	THR46
L	THR47
L	SER64
L	GLY65
L	HOH314
L	HOH337

---

Functional Information from PROSITE/UniProt

site_id	PS01335
Number of Residues	9
Details	METHYLGLYOXAL_SYNTH Methylglyoxal synthase active site. SGPLGGDqQ

Chain	Residue	Details
A	SER64-GLN72

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