6PHE
Crystal structure of Methylglyoxal synthase from Elizabethkingia anophelis NUHP1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0008929 | molecular_function | methylglyoxal synthase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019242 | biological_process | methylglyoxal biosynthetic process |
| B | 0005829 | cellular_component | cytosol |
| B | 0008929 | molecular_function | methylglyoxal synthase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0019242 | biological_process | methylglyoxal biosynthetic process |
| C | 0005829 | cellular_component | cytosol |
| C | 0008929 | molecular_function | methylglyoxal synthase activity |
| C | 0016829 | molecular_function | lyase activity |
| C | 0019242 | biological_process | methylglyoxal biosynthetic process |
| D | 0005829 | cellular_component | cytosol |
| D | 0008929 | molecular_function | methylglyoxal synthase activity |
| D | 0016829 | molecular_function | lyase activity |
| D | 0019242 | biological_process | methylglyoxal biosynthetic process |
| E | 0005829 | cellular_component | cytosol |
| E | 0008929 | molecular_function | methylglyoxal synthase activity |
| E | 0016829 | molecular_function | lyase activity |
| E | 0019242 | biological_process | methylglyoxal biosynthetic process |
| F | 0005829 | cellular_component | cytosol |
| F | 0008929 | molecular_function | methylglyoxal synthase activity |
| F | 0016829 | molecular_function | lyase activity |
| F | 0019242 | biological_process | methylglyoxal biosynthetic process |
| G | 0005829 | cellular_component | cytosol |
| G | 0008929 | molecular_function | methylglyoxal synthase activity |
| G | 0016829 | molecular_function | lyase activity |
| G | 0019242 | biological_process | methylglyoxal biosynthetic process |
| H | 0005829 | cellular_component | cytosol |
| H | 0008929 | molecular_function | methylglyoxal synthase activity |
| H | 0016829 | molecular_function | lyase activity |
| H | 0019242 | biological_process | methylglyoxal biosynthetic process |
| I | 0005829 | cellular_component | cytosol |
| I | 0008929 | molecular_function | methylglyoxal synthase activity |
| I | 0016829 | molecular_function | lyase activity |
| I | 0019242 | biological_process | methylglyoxal biosynthetic process |
| J | 0005829 | cellular_component | cytosol |
| J | 0008929 | molecular_function | methylglyoxal synthase activity |
| J | 0016829 | molecular_function | lyase activity |
| J | 0019242 | biological_process | methylglyoxal biosynthetic process |
| K | 0005829 | cellular_component | cytosol |
| K | 0008929 | molecular_function | methylglyoxal synthase activity |
| K | 0016829 | molecular_function | lyase activity |
| K | 0019242 | biological_process | methylglyoxal biosynthetic process |
| L | 0005829 | cellular_component | cytosol |
| L | 0008929 | molecular_function | methylglyoxal synthase activity |
| L | 0016829 | molecular_function | lyase activity |
| L | 0019242 | biological_process | methylglyoxal biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 A 200 |
| Chain | Residue |
| A | LYS22 |
| A | THR44 |
| A | THR46 |
| A | THR47 |
| A | SER64 |
| A | GLY65 |
| A | HOH308 |
| A | HOH346 |
| F | ARG148 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 B 200 |
| Chain | Residue |
| B | LYS22 |
| B | THR44 |
| B | THR46 |
| B | THR47 |
| B | SER64 |
| B | GLY65 |
| B | HOH308 |
| B | HOH327 |
| C | ARG148 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 C 200 |
| Chain | Residue |
| B | ARG148 |
| C | LYS22 |
| C | THR44 |
| C | THR46 |
| C | THR47 |
| C | SER64 |
| C | GLY65 |
| C | HOH307 |
| C | HOH335 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue MPD C 201 |
| Chain | Residue |
| C | GLU52 |
| C | GLY56 |
| C | GLU58 |
| H | THR37 |
| H | HOH316 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 D 200 |
| Chain | Residue |
| D | LYS22 |
| D | THR44 |
| D | THR46 |
| D | THR47 |
| D | SER64 |
| D | GLY65 |
| D | HOH307 |
| D | HOH331 |
| E | ARG148 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 E 201 |
| Chain | Residue |
| D | ARG148 |
| E | LYS22 |
| E | THR44 |
| E | THR46 |
| E | THR47 |
| E | SER64 |
| E | GLY65 |
| E | HOH309 |
| E | HOH323 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue MPD E 202 |
| Chain | Residue |
| E | PHE130 |
| E | GLU134 |
| E | TYR135 |
| E | GLN136 |
| E | HOH346 |
| E | HOH356 |
| L | PHE130 |
| L | GLU134 |
| L | TYR135 |
| L | GLN136 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 F 200 |
| Chain | Residue |
| A | ARG148 |
| F | LYS22 |
| F | THR44 |
| F | THR46 |
| F | THR47 |
| F | SER64 |
| F | GLY65 |
| F | HOH303 |
| F | HOH340 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 G 200 |
| Chain | Residue |
| G | LYS22 |
| G | THR44 |
| G | THR46 |
| G | THR47 |
| G | SER64 |
| G | GLY65 |
| G | HOH310 |
| G | HOH325 |
| L | ARG148 |
| site_id | AD1 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 H 200 |
| Chain | Residue |
| H | LYS22 |
| H | THR44 |
| H | THR46 |
| H | THR47 |
| H | SER64 |
| H | GLY65 |
| H | HOH310 |
| I | ARG148 |
| I | HOH346 |
| site_id | AD2 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 I 200 |
| Chain | Residue |
| H | ARG148 |
| I | LYS22 |
| I | THR44 |
| I | THR46 |
| I | THR47 |
| I | SER64 |
| I | GLY65 |
| I | HOH302 |
| I | HOH312 |
| site_id | AD3 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 J 200 |
| Chain | Residue |
| J | THR47 |
| J | SER64 |
| J | GLY65 |
| J | HOH302 |
| J | HOH309 |
| K | ARG148 |
| J | LYS22 |
| J | THR44 |
| J | THR46 |
| site_id | AD4 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 K 200 |
| Chain | Residue |
| J | ARG148 |
| K | LYS22 |
| K | THR44 |
| K | THR46 |
| K | THR47 |
| K | SER64 |
| K | GLY65 |
| K | HOH313 |
| K | HOH319 |
| site_id | AD5 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 L 200 |
| Chain | Residue |
| G | ARG148 |
| L | LYS22 |
| L | THR44 |
| L | THR46 |
| L | THR47 |
| L | SER64 |
| L | GLY65 |
| L | HOH314 |
| L | HOH337 |
Functional Information from PROSITE/UniProt
| site_id | PS01335 |
| Number of Residues | 9 |
| Details | METHYLGLYOXAL_SYNTH Methylglyoxal synthase active site. SGPLGGDqQ |
| Chain | Residue | Details |
| A | SER64-GLN72 |
