Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 30 |
| Details | binding site for residue NAP A 501 |
| Chain | Residue |
| A | LEU16 |
| A | ALA98 |
| A | SER100 |
| A | VAL104 |
| A | TYR150 |
| A | ALA152 |
| A | ALA153 |
| A | THR154 |
| A | ARG360 |
| A | GLU364 |
| A | EDO503 |
| A | GLY17 |
| A | HOH628 |
| A | HOH639 |
| A | HOH643 |
| A | HOH659 |
| A | HOH663 |
| A | HOH708 |
| A | HOH717 |
| A | HOH750 |
| A | HOH802 |
| A | HOH829 |
| A | ALA18 |
| A | HOH855 |
| A | VAL19 |
| A | ASN39 |
| A | HIS40 |
| A | ARG44 |
| A | CYS95 |
| A | PRO97 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | binding site for residue O7J A 502 |
| Chain | Residue |
| A | ALA153 |
| A | LYS168 |
| A | VAL214 |
| A | THR215 |
| A | VAL218 |
| A | HIS219 |
| A | TYR243 |
| A | TYR289 |
| A | ARG319 |
| A | TYR320 |
| A | PHE340 |
| A | VAL343 |
| A | HOH647 |
| A | HOH657 |
| A | HOH665 |
| A | HOH686 |
| A | HOH700 |
| A | HOH704 |
| A | HOH735 |
| A | HOH814 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | ASN39 |
| A | HIS40 |
| A | NAP501 |
| A | HOH773 |
| A | HOH798 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | LEU278 |
| A | ASN279 |
| A | ARG282 |
| A | HOH681 |
| A | HOH711 |
| A | HOH756 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | GLU226 |
| A | PHE227 |
| A | PRO250 |
| A | THR252 |
| A | HOH607 |
| A | HOH767 |
| A | HOH793 |
| A | HOH831 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | GLY257 |
| A | ARG261 |
| A | GLU313 |
| A | HOH612 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 507 |
| Chain | Residue |
| A | TRP263 |
| A | CYS264 |
| A | ARG271 |
| A | HOH723 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 508 |
| Chain | Residue |
| A | PRO327 |
| A | SER329 |
| A | HIS337 |
| B | TYR246 |
| site_id | AC9 |
| Number of Residues | 32 |
| Details | binding site for residue NAP B 501 |
| Chain | Residue |
| B | HOH603 |
| B | HOH611 |
| B | HOH621 |
| B | HOH629 |
| B | HOH631 |
| B | HOH659 |
| B | HOH664 |
| B | HOH668 |
| B | HOH692 |
| B | HOH700 |
| B | HOH750 |
| B | HOH763 |
| B | HOH786 |
| B | HOH855 |
| B | GLY15 |
| B | LEU16 |
| B | GLY17 |
| B | ALA18 |
| B | VAL19 |
| B | ASN39 |
| B | HIS40 |
| B | ARG44 |
| B | CYS95 |
| B | VAL96 |
| B | PRO97 |
| B | VAL104 |
| B | TYR150 |
| B | ALA152 |
| B | ALA153 |
| B | THR154 |
| B | ARG360 |
| B | GLU364 |
| site_id | AD1 |
| Number of Residues | 17 |
| Details | binding site for residue O7J B 502 |
| Chain | Residue |
| B | VAL214 |
| B | THR215 |
| B | VAL218 |
| B | HIS219 |
| B | MET242 |
| B | TYR243 |
| B | TYR289 |
| B | ARG319 |
| B | TYR320 |
| B | PHE340 |
| B | HOH619 |
| B | HOH640 |
| B | HOH643 |
| B | HOH683 |
| B | HOH699 |
| B | HOH759 |
| B | HOH775 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 503 |
| Chain | Residue |
| B | GLU226 |
| B | PHE227 |
| B | PRO250 |
| B | THR252 |
| B | HOH626 |
| B | HOH764 |
| B | HOH862 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 504 |
| Chain | Residue |
| B | ASP99 |
| B | ARG367 |
| B | LYS368 |
| B | LEU371 |
| B | HOH630 |
| B | HOH658 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 40 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"UniProtKB","id":"Q8CKU7","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"29618515","evidenceCode":"ECO:0000269"}]} |
