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6PAS

Inactive State of Manduca sexta soluble guanylate cyclase

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0004383molecular_functionguanylate cyclase activity
A0005525molecular_functionGTP binding
A0005737cellular_componentcytoplasm
A0006182biological_processcGMP biosynthetic process
A0008074cellular_componentguanylate cyclase complex, soluble
A0009190biological_processcyclic nucleotide biosynthetic process
A0009975molecular_functioncyclase activity
A0016829molecular_functionlyase activity
A0016849molecular_functionphosphorus-oxygen lyase activity
A0019934biological_processcGMP-mediated signaling
A0020037molecular_functionheme binding
A0035556biological_processintracellular signal transduction
A0070482biological_processresponse to oxygen levels
B0004383molecular_functionguanylate cyclase activity
B0005525molecular_functionGTP binding
B0005737cellular_componentcytoplasm
B0006182biological_processcGMP biosynthetic process
B0008074cellular_componentguanylate cyclase complex, soluble
B0009190biological_processcyclic nucleotide biosynthetic process
B0009975molecular_functioncyclase activity
B0016829molecular_functionlyase activity
B0016849molecular_functionphosphorus-oxygen lyase activity
B0019934biological_processcGMP-mediated signaling
B0020037molecular_functionheme binding
B0035556biological_processintracellular signal transduction
B0070482biological_processresponse to oxygen levels
Functional Information from PDB Data
site_idAC1
Number of Residues5
Detailsbinding site for residue HEM B 701
ChainResidue
BMET1
BTYR2
BARG116
BSER117
BPRO118

Functional Information from PROSITE/UniProt
site_idPS00452
Number of Residues24
DetailsGUANYLATE_CYCLASE_1 Guanylate cyclase signature. GVI.GhrmprYcLFGNTVNltsrcE
ChainResidueDetails
BGLY522-GLU545
AGLY586-GLU609

237992

PDB entries from 2025-06-25

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