Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6P8L

Escherichia coli Bacterioferritin Substituted with Zinc Protoporphyrin IX (Zn Absorption Edge X-ray Data)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004322	molecular_function	ferroxidase activity
A	0005506	molecular_function	iron ion binding
A	0005515	molecular_function	protein binding
A	0005829	cellular_component	cytosol
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0008199	molecular_function	ferric iron binding
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0020037	molecular_function	heme binding
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0046872	molecular_function	metal ion binding
A	0140315	molecular_function	iron ion sequestering activity
B	0004322	molecular_function	ferroxidase activity
B	0005506	molecular_function	iron ion binding
B	0005515	molecular_function	protein binding
B	0005829	cellular_component	cytosol
B	0006826	biological_process	iron ion transport
B	0006879	biological_process	intracellular iron ion homeostasis
B	0008199	molecular_function	ferric iron binding
B	0016020	cellular_component	membrane
B	0016491	molecular_function	oxidoreductase activity
B	0020037	molecular_function	heme binding
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0046872	molecular_function	metal ion binding
B	0140315	molecular_function	iron ion sequestering activity
C	0004322	molecular_function	ferroxidase activity
C	0005506	molecular_function	iron ion binding
C	0005515	molecular_function	protein binding
C	0005829	cellular_component	cytosol
C	0006826	biological_process	iron ion transport
C	0006879	biological_process	intracellular iron ion homeostasis
C	0008199	molecular_function	ferric iron binding
C	0016020	cellular_component	membrane
C	0016491	molecular_function	oxidoreductase activity
C	0020037	molecular_function	heme binding
C	0042802	molecular_function	identical protein binding
C	0042803	molecular_function	protein homodimerization activity
C	0046872	molecular_function	metal ion binding
C	0140315	molecular_function	iron ion sequestering activity
D	0004322	molecular_function	ferroxidase activity
D	0005506	molecular_function	iron ion binding
D	0005515	molecular_function	protein binding
D	0005829	cellular_component	cytosol
D	0006826	biological_process	iron ion transport
D	0006879	biological_process	intracellular iron ion homeostasis
D	0008199	molecular_function	ferric iron binding
D	0016020	cellular_component	membrane
D	0016491	molecular_function	oxidoreductase activity
D	0020037	molecular_function	heme binding
D	0042802	molecular_function	identical protein binding
D	0042803	molecular_function	protein homodimerization activity
D	0046872	molecular_function	metal ion binding
D	0140315	molecular_function	iron ion sequestering activity
E	0004322	molecular_function	ferroxidase activity
E	0005506	molecular_function	iron ion binding
E	0005515	molecular_function	protein binding
E	0005829	cellular_component	cytosol
E	0006826	biological_process	iron ion transport
E	0006879	biological_process	intracellular iron ion homeostasis
E	0008199	molecular_function	ferric iron binding
E	0016020	cellular_component	membrane
E	0016491	molecular_function	oxidoreductase activity
E	0020037	molecular_function	heme binding
E	0042802	molecular_function	identical protein binding
E	0042803	molecular_function	protein homodimerization activity
E	0046872	molecular_function	metal ion binding
E	0140315	molecular_function	iron ion sequestering activity
F	0004322	molecular_function	ferroxidase activity
F	0005506	molecular_function	iron ion binding
F	0005515	molecular_function	protein binding
F	0005829	cellular_component	cytosol
F	0006826	biological_process	iron ion transport
F	0006879	biological_process	intracellular iron ion homeostasis
F	0008199	molecular_function	ferric iron binding
F	0016020	cellular_component	membrane
F	0016491	molecular_function	oxidoreductase activity
F	0020037	molecular_function	heme binding
F	0042802	molecular_function	identical protein binding
F	0042803	molecular_function	protein homodimerization activity
F	0046872	molecular_function	metal ion binding
F	0140315	molecular_function	iron ion sequestering activity
G	0004322	molecular_function	ferroxidase activity
G	0005506	molecular_function	iron ion binding
G	0005515	molecular_function	protein binding
G	0005829	cellular_component	cytosol
G	0006826	biological_process	iron ion transport
G	0006879	biological_process	intracellular iron ion homeostasis
G	0008199	molecular_function	ferric iron binding
G	0016020	cellular_component	membrane
G	0016491	molecular_function	oxidoreductase activity
G	0020037	molecular_function	heme binding
G	0042802	molecular_function	identical protein binding
G	0042803	molecular_function	protein homodimerization activity
G	0046872	molecular_function	metal ion binding
G	0140315	molecular_function	iron ion sequestering activity
H	0004322	molecular_function	ferroxidase activity
H	0005506	molecular_function	iron ion binding
H	0005515	molecular_function	protein binding
H	0005829	cellular_component	cytosol
H	0006826	biological_process	iron ion transport
H	0006879	biological_process	intracellular iron ion homeostasis
H	0008199	molecular_function	ferric iron binding
H	0016020	cellular_component	membrane
H	0016491	molecular_function	oxidoreductase activity
H	0020037	molecular_function	heme binding
H	0042802	molecular_function	identical protein binding
H	0042803	molecular_function	protein homodimerization activity
H	0046872	molecular_function	metal ion binding
H	0140315	molecular_function	iron ion sequestering activity
I	0004322	molecular_function	ferroxidase activity
I	0005506	molecular_function	iron ion binding
I	0005515	molecular_function	protein binding
I	0005829	cellular_component	cytosol
I	0006826	biological_process	iron ion transport
I	0006879	biological_process	intracellular iron ion homeostasis
I	0008199	molecular_function	ferric iron binding
I	0016020	cellular_component	membrane
I	0016491	molecular_function	oxidoreductase activity
I	0020037	molecular_function	heme binding
I	0042802	molecular_function	identical protein binding
I	0042803	molecular_function	protein homodimerization activity
I	0046872	molecular_function	metal ion binding
I	0140315	molecular_function	iron ion sequestering activity
J	0004322	molecular_function	ferroxidase activity
J	0005506	molecular_function	iron ion binding
J	0005515	molecular_function	protein binding
J	0005829	cellular_component	cytosol
J	0006826	biological_process	iron ion transport
J	0006879	biological_process	intracellular iron ion homeostasis
J	0008199	molecular_function	ferric iron binding
J	0016020	cellular_component	membrane
J	0016491	molecular_function	oxidoreductase activity
J	0020037	molecular_function	heme binding
J	0042802	molecular_function	identical protein binding
J	0042803	molecular_function	protein homodimerization activity
J	0046872	molecular_function	metal ion binding
J	0140315	molecular_function	iron ion sequestering activity
K	0004322	molecular_function	ferroxidase activity
K	0005506	molecular_function	iron ion binding
K	0005515	molecular_function	protein binding
K	0005829	cellular_component	cytosol
K	0006826	biological_process	iron ion transport
K	0006879	biological_process	intracellular iron ion homeostasis
K	0008199	molecular_function	ferric iron binding
K	0016020	cellular_component	membrane
K	0016491	molecular_function	oxidoreductase activity
K	0020037	molecular_function	heme binding
K	0042802	molecular_function	identical protein binding
K	0042803	molecular_function	protein homodimerization activity
K	0046872	molecular_function	metal ion binding
K	0140315	molecular_function	iron ion sequestering activity
L	0004322	molecular_function	ferroxidase activity
L	0005506	molecular_function	iron ion binding
L	0005515	molecular_function	protein binding
L	0005829	cellular_component	cytosol
L	0006826	biological_process	iron ion transport
L	0006879	biological_process	intracellular iron ion homeostasis
L	0008199	molecular_function	ferric iron binding
L	0016020	cellular_component	membrane
L	0016491	molecular_function	oxidoreductase activity
L	0020037	molecular_function	heme binding
L	0042802	molecular_function	identical protein binding
L	0042803	molecular_function	protein homodimerization activity
L	0046872	molecular_function	metal ion binding
L	0140315	molecular_function	iron ion sequestering activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 201

Chain	Residue
A	GLU18
A	GLU51
A	HIS54
A	GLU127

site_id	AC2
Number of Residues	6
Details	binding site for residue NA A 202

Chain	Residue
C	HOH331
A	ASN148
A	ASN148
C	ASN148
C	ASN148
C	HOH331

site_id	AC3
Number of Residues	6
Details	binding site for residue MLI A 203

Chain	Residue
A	ARG57
A	MET119
A	HOH302
A	HOH330
A	HOH373
J	ARG125

site_id	AC4
Number of Residues	6
Details	binding site for residue MLI A 204

Chain	Residue
A	ARG117
A	ASP118
A	HOH331
D	ARG117
D	ASP118
J	ARG117

site_id	AC5
Number of Residues	4
Details	binding site for residue MLI A 205

Chain	Residue
A	GLY145
A	LEU146
A	GLN147
A	HOH351

site_id	AC6
Number of Residues	16
Details	binding site for residue ZNH B 201

Chain	Residue
A	LEU19
A	ILE22
A	ASN23
A	TYR45
A	MET52
A	LYS53
A	HOH337
B	LEU19
B	ILE22
B	ASN23
B	PHE26
B	TYR45
B	ILE49
B	MET52
B	LYS53
B	HOH359

site_id	AC7
Number of Residues	4
Details	binding site for residue ZN B 202

Chain	Residue
B	GLU18
B	GLU51
B	HIS54
B	GLU127

site_id	AC8
Number of Residues	6
Details	binding site for residue NA B 203

Chain	Residue
B	ASN148
G	ASN148
G	HOH410
J	ASN148
K	ASN148
K	HOH340

site_id	AC9
Number of Residues	6
Details	binding site for residue MLI B 204

Chain	Residue
B	ARG57
B	MET119
B	HOH301
B	HOH316
B	HOH319
C	ARG125

site_id	AD1
Number of Residues	7
Details	binding site for residue MLI B 205

Chain	Residue
B	ARG117
B	ASP118
B	ILE121
C	ARG117
H	ARG117
H	ASP118
H	ILE121

site_id	AD2
Number of Residues	6
Details	binding site for residue MLI B 206

Chain	Residue
B	LEU146
B	GLN147
B	HOH346
B	HOH358
B	HOH365
B	HOH366

site_id	AD3
Number of Residues	4
Details	binding site for residue ZN C 201

Chain	Residue
C	GLU18
C	GLU51
C	HIS54
C	GLU127

site_id	AD4
Number of Residues	7
Details	binding site for residue MLI C 202

Chain	Residue
C	ARG57
C	MET119
C	HOH307
C	HOH314
C	HOH337
C	HOH346
H	ARG125

site_id	AD5
Number of Residues	4
Details	binding site for residue MLI C 203

Chain	Residue
C	GLY145
C	LEU146
C	GLN147
C	HOH342

site_id	AD6
Number of Residues	18
Details	binding site for residue ZNH D 201

Chain	Residue
D	MET52
D	LYS53
D	HOH301
D	HOH315
D	HOH340
C	LEU19
C	ILE22
C	ASN23
C	TYR45
C	MET52
C	ALA55
C	HOH347
D	LEU19
D	ILE22
D	ASN23
D	PHE26
D	TYR45
D	ILE49

site_id	AD7
Number of Residues	4
Details	binding site for residue ZN D 202

Chain	Residue
D	GLU18
D	GLU51
D	HIS54
D	GLU127

site_id	AD8
Number of Residues	6
Details	binding site for residue NA D 203

Chain	Residue
D	ASN148
E	ASN148
H	ASN148
H	HOH412
I	ASN148
I	HOH341

site_id	AD9
Number of Residues	6
Details	binding site for residue MLI D 204

Chain	Residue
A	ARG125
D	ARG57
D	MET119
D	HOH304
D	HOH328
D	HOH334

site_id	AE1
Number of Residues	6
Details	binding site for residue MLI D 205

Chain	Residue
D	GLY145
D	LEU146
D	GLN147
D	HOH322
D	HOH348
D	HOH357

site_id	AE2
Number of Residues	4
Details	binding site for residue ZN E 201

Chain	Residue
E	GLU18
E	GLU51
E	HIS54
E	GLU127

site_id	AE3
Number of Residues	6
Details	binding site for residue MLI E 202

Chain	Residue
E	ARG57
E	MET119
E	HOH304
E	HOH311
E	HOH371
L	ARG125

site_id	AE4
Number of Residues	6
Details	binding site for residue MLI E 203

Chain	Residue
E	GLY145
E	LEU146
E	GLN147
E	HOH318
E	HOH320
E	HOH321

site_id	AE5
Number of Residues	17
Details	binding site for residue ZNH F 201

Chain	Residue
E	LEU19
E	ILE22
E	ASN23
E	PHE26
E	TYR45
E	MET52
E	LYS53
E	HOH357
F	LEU19
F	ILE22
F	ASN23
F	PHE26
F	TYR45
F	ILE49
F	MET52
F	LYS53
F	ALA55

site_id	AE6
Number of Residues	4
Details	binding site for residue ZN F 202

Chain	Residue
F	GLU18
F	GLU51
F	HIS54
F	GLU127

site_id	AE7
Number of Residues	6
Details	binding site for residue NA F 203

Chain	Residue
F	ASN148
F	ASN148
F	HOH417
F	HOH417
L	ASN148
L	ASN148

site_id	AE8
Number of Residues	6
Details	binding site for residue MLI F 204

Chain	Residue
F	ARG57
F	MET119
F	HOH304
F	HOH336
F	HOH357
I	ARG125

site_id	AE9
Number of Residues	4
Details	binding site for residue MLI F 205

Chain	Residue
F	GLY145
F	LEU146
F	GLN147
F	HOH331

site_id	AF1
Number of Residues	4
Details	binding site for residue ZN G 201

Chain	Residue
G	GLU18
G	GLU51
G	HIS54
G	GLU127

site_id	AF2
Number of Residues	5
Details	binding site for residue MLI G 202

Chain	Residue
E	ARG125
G	ARG57
G	MET119
G	HOH301
G	HOH317

site_id	AF3
Number of Residues	5
Details	binding site for residue MLI G 203

Chain	Residue
G	GLY145
G	LEU146
G	GLN147
G	HOH340
G	HOH355

site_id	AF4
Number of Residues	7
Details	binding site for residue MLI G 204

Chain	Residue
E	ARG117
E	HOH345
G	ARG117
G	ASP118
L	ARG117
L	ASP118
L	ILE121

site_id	AF5
Number of Residues	16
Details	binding site for residue ZNH H 201

Chain	Residue
G	LEU19
G	ILE22
G	ASN23
G	PHE26
G	TYR45
G	ILE49
G	MET52
G	LYS53
G	HOH338
H	LEU19
H	ILE22
H	ASN23
H	TYR45
H	MET52
H	LYS53
H	HOH339

site_id	AF6
Number of Residues	4
Details	binding site for residue ZN H 202

Chain	Residue
H	GLU18
H	GLU51
H	HIS54
H	GLU127

site_id	AF7
Number of Residues	7
Details	binding site for residue MLI H 203

Chain	Residue
B	ARG125
H	ARG57
H	MET119
H	HOH302
H	HOH347
H	HOH349
H	HOH372

site_id	AF8
Number of Residues	6
Details	binding site for residue MLI H 204

Chain	Residue
H	GLY145
H	LEU146
H	GLN147
H	HOH332
H	HOH335
H	HOH389

site_id	AF9
Number of Residues	4
Details	binding site for residue ZN I 201

Chain	Residue
I	GLU18
I	GLU51
I	HIS54
I	GLU127

site_id	AG1
Number of Residues	6
Details	binding site for residue MLI I 202

Chain	Residue
I	ARG57
I	MET119
I	HOH305
I	HOH333
I	HOH334
K	ARG125

site_id	AG2
Number of Residues	6
Details	binding site for residue MLI I 203

Chain	Residue
I	GLY145
I	LEU146
I	GLN147
I	HOH310
I	HOH317
I	HOH379

site_id	AG3
Number of Residues	17
Details	binding site for residue ZNH J 201

Chain	Residue
I	LEU19
I	ILE22
I	ASN23
I	PHE26
I	TYR45
I	MET52
I	LYS53
I	HOH312
I	HOH376
J	LEU19
J	ILE22
J	ASN23
J	PHE26
J	TYR45
J	MET52
J	LYS53
J	HOH366

site_id	AG4
Number of Residues	4
Details	binding site for residue ZN J 202

Chain	Residue
J	GLU18
J	GLU51
J	HIS54
J	GLU127

site_id	AG5
Number of Residues	7
Details	binding site for residue MLI J 203

Chain	Residue
D	ARG125
J	ARG57
J	MET119
J	HOH306
J	HOH338
J	HOH345
J	HOH375

site_id	AG6
Number of Residues	4
Details	binding site for residue MLI J 204

Chain	Residue
J	GLY145
J	LEU146
J	GLN147
J	HOH371

site_id	AG7
Number of Residues	7
Details	binding site for residue MLI K 201

Chain	Residue
F	ARG117
F	HOH334
I	ARG117
I	ASP118
K	ARG117
K	ASP118
K	HOH304

site_id	AG8
Number of Residues	4
Details	binding site for residue ZN K 202

Chain	Residue
K	GLU18
K	GLU51
K	HIS54
K	GLU127

site_id	AG9
Number of Residues	6
Details	binding site for residue MLI K 203

Chain	Residue
F	ARG125
K	ARG57
K	MET119
K	HOH303
K	HOH319
K	HOH361

site_id	AH1
Number of Residues	5
Details	binding site for residue MLI K 204

Chain	Residue
K	GLY145
K	LEU146
K	GLN147
K	HOH312
K	HOH368

site_id	AH2
Number of Residues	15
Details	binding site for residue ZNH L 201

Chain	Residue
K	LEU19
K	ILE22
K	ASN23
K	PHE26
K	TYR45
K	MET52
L	LEU19
L	ILE22
L	ASN23
L	PHE26
L	TYR45
L	ILE49
L	MET52
L	LYS53
L	HOH354

site_id	AH3
Number of Residues	4
Details	binding site for residue ZN L 202

Chain	Residue
L	GLU18
L	GLU51
L	HIS54
L	GLU127

site_id	AH4
Number of Residues	7
Details	binding site for residue MLI L 203

Chain	Residue
G	ARG125
L	ARG57
L	MET119
L	HOH301
L	HOH307
L	HOH331
L	HOH338

site_id	AH5
Number of Residues	5
Details	binding site for residue MLI L 204

Chain	Residue
L	GLY145
L	LEU146
L	GLN147
L	HOH315
L	HOH316

Functional Information from PROSITE/UniProt

site_id	PS00549
Number of Residues	19
Details	BACTERIOFERRITIN Bacterioferritin signature. MkGdtkVInyLnklLgneL

Chain	Residue	Details
A	MET1-LEU19

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1728
Details	Domain: {"description":"Ferritin-like diiron","evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	96
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17077480","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	12
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17077480","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)