6P83
E.coli LpxD in complex with compound 1o
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005515 | molecular_function | protein binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0009245 | biological_process | lipid A biosynthetic process |
A | 0016410 | molecular_function | N-acyltransferase activity |
A | 0016740 | molecular_function | transferase activity |
A | 0016746 | molecular_function | acyltransferase activity |
A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
A | 0042802 | molecular_function | identical protein binding |
A | 0046677 | biological_process | response to antibiotic |
A | 0103118 | molecular_function | UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity |
B | 0005515 | molecular_function | protein binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0005829 | cellular_component | cytosol |
B | 0009245 | biological_process | lipid A biosynthetic process |
B | 0016410 | molecular_function | N-acyltransferase activity |
B | 0016740 | molecular_function | transferase activity |
B | 0016746 | molecular_function | acyltransferase activity |
B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
B | 0042802 | molecular_function | identical protein binding |
B | 0046677 | biological_process | response to antibiotic |
B | 0103118 | molecular_function | UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity |
C | 0005515 | molecular_function | protein binding |
C | 0005737 | cellular_component | cytoplasm |
C | 0005829 | cellular_component | cytosol |
C | 0009245 | biological_process | lipid A biosynthetic process |
C | 0016410 | molecular_function | N-acyltransferase activity |
C | 0016740 | molecular_function | transferase activity |
C | 0016746 | molecular_function | acyltransferase activity |
C | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
C | 0042802 | molecular_function | identical protein binding |
C | 0046677 | biological_process | response to antibiotic |
C | 0103118 | molecular_function | UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | binding site for residue MG A 401 |
Chain | Residue |
A | HOH590 |
A | HOH761 |
B | HOH729 |
B | HOH895 |
C | HOH674 |
C | HOH911 |
site_id | AC2 |
Number of Residues | 6 |
Details | binding site for residue MG A 402 |
Chain | Residue |
B | HOH754 |
C | ASN121 |
C | HOH634 |
A | ASN121 |
A | HOH555 |
B | ASN121 |
site_id | AC3 |
Number of Residues | 14 |
Details | binding site for residue O3Y A 403 |
Chain | Residue |
A | ALA250 |
A | MET266 |
A | ILE267 |
A | GLY268 |
A | GLY269 |
A | THR284 |
A | VAL285 |
A | HOH534 |
A | HOH565 |
A | HOH574 |
C | PHE183 |
C | TYR185 |
C | ILE254 |
C | ALA256 |
site_id | AC4 |
Number of Residues | 16 |
Details | binding site for residue O3Y B 501 |
Chain | Residue |
A | PHE183 |
A | TYR185 |
A | ILE254 |
A | ALA256 |
B | ALA250 |
B | MET266 |
B | ILE267 |
B | GLY268 |
B | GLY269 |
B | VAL285 |
B | HOH636 |
B | HOH661 |
B | HOH677 |
B | HOH741 |
C | GLU49 |
C | LYS70 |
site_id | AC5 |
Number of Residues | 17 |
Details | binding site for residue O3Y C 501 |
Chain | Residue |
B | GLU49 |
B | LYS70 |
B | PHE183 |
B | TYR185 |
B | ILE254 |
B | ASN274 |
B | HOH672 |
C | ALA250 |
C | MET266 |
C | ILE267 |
C | GLY268 |
C | GLY269 |
C | VAL285 |
C | HOH620 |
C | HOH665 |
C | HOH695 |
C | HOH840 |
Functional Information from PROSITE/UniProt
site_id | PS00101 |
Number of Residues | 29 |
Details | HEXAPEP_TRANSFERASES Hexapeptide-repeat containing-transferases signature. IApsAvIdatAkLGnnVsIGanAvIesgV |
Chain | Residue | Details |
A | ILE100-VAL128 | |
A | ILE106-VAL134 | |
A | LEU130-VAL158 | |
A | ILE225-VAL253 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | ACT_SITE: Proton acceptor => ECO:0000269|PubMed:18422345 |
Chain | Residue | Details |
A | HIS239 | |
B | HIS239 | |
C | HIS239 |
site_id | SWS_FT_FI2 |
Number of Residues | 3 |
Details | SITE: Involved in determining the hydroxyacyl-ACP selectivity |
Chain | Residue | Details |
A | MET290 | |
B | MET290 | |
C | MET290 |