6P6C

CS-Rosetta Model of PEA-15 Death Effector Domain in the Complex with ERK2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000165	biological_process	MAPK cascade
A	0005515	molecular_function	protein binding
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005875	cellular_component	microtubule associated complex
A	0006915	biological_process	apoptotic process
A	0042981	biological_process	regulation of apoptotic process
A	0043231	cellular_component	intracellular membrane-bounded organelle
A	0046325	biological_process	negative regulation of glucose import
A	0071702	biological_process	organic substance transport
A	1902042	biological_process	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
A	1902043	biological_process	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231

Chain	Residue	Details
A	SER61

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q62048

Chain	Residue	Details
A	SER90

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER104

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	SER116

---