Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 301 |
| Chain | Residue |
| A | ASP189 |
| A | GLY191 |
| A | HOH535 |
| A | HOH539 |
| A | HOH567 |
| A | HOH589 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 302 |
| Chain | Residue |
| A | GLY95 |
| A | HOH582 |
| A | ASP19 |
| A | GLY21 |
| A | TYR92 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue MPD A 304 |
| Chain | Residue |
| A | ARG217 |
| A | HOH578 |
| B | ALA132 |
| B | THR174 |
| B | GLY175 |
| B | HOH474 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue MPD A 305 |
| Chain | Residue |
| A | LEU162 |
| A | GLU209 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | binding site for residue GES A 306 |
| Chain | Residue |
| A | GLN20 |
| A | GLY24 |
| A | SER25 |
| A | CYS26 |
| A | TRP27 |
| A | ASN62 |
| A | SER65 |
| A | GLY66 |
| A | GLY67 |
| A | LEU68 |
| A | GLN71 |
| A | ASN163 |
| A | HIS164 |
| A | HOH434 |
| A | HOH557 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 301 |
| Chain | Residue |
| B | ASP189 |
| B | GLY191 |
| B | HOH559 |
| B | HOH564 |
| B | HOH581 |
| B | HOH593 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue ACT B 302 |
| Chain | Residue |
| B | GLU10 |
| B | LYS11 |
| B | ARG197 |
| B | HOH583 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue ACT B 303 |
| Chain | Residue |
| B | LYS125 |
| B | HOH403 |
| B | HOH406 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | binding site for residue ACT B 304 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue ACT B 305 |
| Chain | Residue |
| B | MET147 |
| B | HOH415 |
| site_id | AD2 |
| Number of Residues | 9 |
| Details | binding site for residue TRS B 306 |
| Chain | Residue |
| B | ASP4 |
| B | ASP4 |
| B | ASP4 |
| B | HOH490 |
| B | HOH490 |
| B | HOH490 |
| B | HOH508 |
| B | HOH508 |
| B | HOH508 |
| site_id | AD3 |
| Number of Residues | 17 |
| Details | binding site for Di-peptide GES B 307 and CYS B 26 |
| Chain | Residue |
| B | GLN20 |
| B | GLY24 |
| B | SER25 |
| B | TRP27 |
| B | ALA28 |
| B | PHE29 |
| B | SER30 |
| B | SER65 |
| B | GLY66 |
| B | GLY67 |
| B | LEU68 |
| B | GLN71 |
| B | ALA140 |
| B | ASN163 |
| B | HIS164 |
| B | GLY165 |
| B | HOH519 |
| site_id | AD4 |
| Number of Residues | 17 |
| Details | binding site for Di-peptide GES B 307 and CYS B 26 |
| Chain | Residue |
| B | GLN20 |
| B | GLY24 |
| B | SER25 |
| B | TRP27 |
| B | ALA28 |
| B | PHE29 |
| B | SER30 |
| B | SER65 |
| B | GLY66 |
| B | GLY67 |
| B | LEU68 |
| B | GLN71 |
| B | ALA140 |
| B | ASN163 |
| B | HIS164 |
| B | GLY165 |
| B | HOH519 |
Functional Information from PROSITE/UniProt
| site_id | PS00139 |
| Number of Residues | 12 |
| Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGaCGSCWAfSA |
| Chain | Residue | Details |
| A | GLN20-ALA31 | |
| site_id | PS00639 |
| Number of Residues | 11 |
| Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. LNHGVLLVGYD |
| Chain | Residue | Details |
| A | LEU162-ASP172 | |
| site_id | PS00640 |
| Number of Residues | 20 |
| Details | THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWViKNSWggdWGeqGYVrV |
| Chain | Residue | Details |
| A | TYR179-VAL198 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250 |
| Chain | Residue | Details |
| A | CYS26 | |
| A | HIS164 | |
| A | ASN184 | |
| B | CYS26 | |
| B | HIS164 | |
| B | ASN184 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN104 | |
| B | ASN104 | |
