6P3M

Tetrahydroprotoberberine N-methyltransferase in complex with S-adenosylhomocysteine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008168	molecular_function	methyltransferase activity
A	0030782	molecular_function	(S)-tetrahydroprotoberberine N-methyltransferase activity
A	0032259	biological_process	methylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	binding site for residue SAH A 401

Chain	Residue
A	GLN98
A	GLU204
A	THR205
A	MET209
A	HOH502
A	HOH513
A	HOH515
A	HOH523
A	HOH531
A	HOH590
A	HOH614
A	SER99
A	HOH685
A	GLY137
A	ASN161
A	GLN165
A	ALA186
A	ASP187
A	VAL188
A	ILE203

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site_id	AC2
Number of Residues	8
Details	binding site for residue SO4 A 402

Chain	Residue
A	PHE38
A	ARG41
A	HIS241
A	HIS242
A	PHE243
A	GLU244
A	ASP250
A	SER253

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