Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008465 | molecular_function | hydroxypyruvate reductase (NADH) activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0016618 | molecular_function | hydroxypyruvate reductase [NAD(P)H] activity |
| A | 0030267 | molecular_function | glyoxylate reductase (NADPH) activity |
| A | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue NWG A 401 |
| Chain | Residue |
| A | HIS46 |
| A | GLY64 |
| A | ALA65 |
| A | GLY66 |
| A | ARG227 |
| A | HIS275 |
| A | NAP405 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | PHE178 |
| A | GLN176 |
| A | SER177 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 403 |
| Chain | Residue |
| A | ASP11 |
| A | NWG404 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue NWG A 404 |
| Chain | Residue |
| A | PHE10 |
| A | ASP11 |
| A | TRP15 |
| A | GLU131 |
| A | THR280 |
| A | PRO282 |
| A | GOL403 |
| A | HOH541 |
| site_id | AC5 |
| Number of Residues | 34 |
| Details | binding site for residue NAP A 405 |
| Chain | Residue |
| A | ALA65 |
| A | ARG89 |
| A | MET99 |
| A | GLY143 |
| A | ALA144 |
| A | GLY145 |
| A | VAL146 |
| A | LEU147 |
| A | TRP165 |
| A | SER166 |
| A | ARG167 |
| A | THR168 |
| A | LYS170 |
| A | LEU197 |
| A | LEU198 |
| A | PRO199 |
| A | LEU225 |
| A | ALA226 |
| A | ARG227 |
| A | ASP251 |
| A | HIS275 |
| A | ALA277 |
| A | ALA278 |
| A | TYR312 |
| A | NWG401 |
| A | HOH504 |
| A | HOH524 |
| A | HOH529 |
| A | HOH539 |
| A | HOH543 |
| A | HOH580 |
| A | HOH583 |
| A | HOH600 |
| A | HOH607 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 406 |
| Chain | Residue |
| A | HIS133 |
| A | ARG134 |
| A | ARG159 |
| A | ARG281 |
| A | HOH511 |
| A | HOH520 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 407 |
| Chain | Residue |
| A | PRO48 |
| A | VAL49 |
| A | LYS73 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 408 |
| Chain | Residue |
| A | ARG113 |
| A | PRO130 |
| A | HOH574 |
Functional Information from PROSITE/UniProt
| site_id | PS00671 |
| Number of Residues | 17 |
| Details | D_2_HYDROXYACID_DH_3 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. LPdGaYLLNlARGvHVV |
| Chain | Residue | Details |
| A | LEU216-VAL232 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250 |
| Chain | Residue | Details |
| A | ARG227 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS275 | |
