6P2V
RebH Variant 10S, Tryptamine 5-halogenase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 27 |
| Details | binding site for residue FAD A 601 |
| Chain | Residue |
| A | GLY12 |
| A | ALA50 |
| A | ASP195 |
| A | ARG196 |
| A | VAL197 |
| A | CYS227 |
| A | SER228 |
| A | GLY229 |
| A | PHE230 |
| A | LEU233 |
| A | ILE328 |
| A | GLY13 |
| A | THR348 |
| A | PHE352 |
| A | PRO355 |
| A | SER358 |
| A | GLY360 |
| A | HOH728 |
| A | HOH729 |
| A | HOH748 |
| A | GLY14 |
| A | THR15 |
| A | ALA16 |
| A | GLN38 |
| A | ALA39 |
| A | GLY48 |
| A | GLU49 |
| site_id | AC2 |
| Number of Residues | 26 |
| Details | binding site for residue FAD B 601 |
| Chain | Residue |
| B | GLY12 |
| B | GLY13 |
| B | GLY14 |
| B | THR15 |
| B | ALA16 |
| B | ALA39 |
| B | ASP41 |
| B | GLY48 |
| B | GLU49 |
| B | ALA50 |
| B | ASP195 |
| B | ARG196 |
| B | VAL197 |
| B | CYS227 |
| B | SER228 |
| B | GLY229 |
| B | PHE230 |
| B | LEU233 |
| B | THR348 |
| B | PRO355 |
| B | SER358 |
| B | GLY360 |
| B | HOH705 |
| B | HOH718 |
| B | HOH721 |
| B | HOH738 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"17260957","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17260957","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17876823","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2OA1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OAL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17260957","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2OAL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17260957","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17876823","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2E4G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OA1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17876823","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2OA1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for activity","evidences":[{"source":"UniProtKB","id":"P95480","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
