Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0051287 | molecular_function | NAD binding |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 39 |
| Details | binding site for residue NAP A 401 |
| Chain | Residue |
| A | SER98 |
| A | LYS173 |
| A | SER174 |
| A | ARG176 |
| A | HIS199 |
| A | ILE200 |
| A | PRO201 |
| A | THR206 |
| A | THR227 |
| A | CYS228 |
| A | ASP253 |
| A | VAL102 |
| A | ALA276 |
| A | TRP277 |
| A | DAR402 |
| A | HOH510 |
| A | HOH522 |
| A | HOH528 |
| A | HOH532 |
| A | HOH561 |
| A | HOH565 |
| A | HOH571 |
| A | GLY149 |
| A | HOH581 |
| A | HOH591 |
| A | HOH595 |
| A | HOH604 |
| A | HOH609 |
| A | HOH640 |
| A | HOH648 |
| A | HOH651 |
| A | HOH704 |
| A | HOH712 |
| A | ILE150 |
| A | GLY151 |
| A | GLN152 |
| A | ILE153 |
| A | LEU171 |
| A | ASN172 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue DAR A 402 |
| Chain | Residue |
| A | GLU51 |
| A | ILE72 |
| A | THR73 |
| A | THR74 |
| A | SER75 |
| A | TYR97 |
| A | ARG229 |
| A | TRP277 |
| A | ASN286 |
| A | NAP401 |
| A | HOH532 |
| A | HOH573 |
| A | HOH615 |
| A | HOH661 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 403 |
| Chain | Residue |
| A | ARG141 |
| A | PHE164 |
| B | GLN100 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 404 |
| site_id | AC5 |
| Number of Residues | 39 |
| Details | binding site for residue NAP B 401 |
| Chain | Residue |
| B | SER98 |
| B | VAL102 |
| B | GLY149 |
| B | ILE150 |
| B | GLY151 |
| B | GLN152 |
| B | ILE153 |
| B | LEU171 |
| B | ASN172 |
| B | LYS173 |
| B | SER174 |
| B | ARG176 |
| B | HIS199 |
| B | ILE200 |
| B | PRO201 |
| B | THR206 |
| B | THR227 |
| B | CYS228 |
| B | ASP253 |
| B | ALA276 |
| B | TRP277 |
| B | DAR402 |
| B | HOH535 |
| B | HOH543 |
| B | HOH552 |
| B | HOH554 |
| B | HOH556 |
| B | HOH562 |
| B | HOH565 |
| B | HOH566 |
| B | HOH576 |
| B | HOH581 |
| B | HOH652 |
| B | HOH655 |
| B | HOH662 |
| B | HOH665 |
| B | HOH669 |
| B | HOH687 |
| B | HOH693 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | binding site for residue DAR B 402 |
| Chain | Residue |
| B | THR74 |
| B | SER75 |
| B | TYR97 |
| B | TRP277 |
| B | ASN286 |
| B | NAP401 |
| B | HOH576 |
| B | HOH577 |
| B | HOH617 |
| B | HOH629 |
| B | HOH667 |
| B | GLU51 |
| B | ILE72 |
| B | THR73 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 403 |
| Chain | Residue |
| A | GLN100 |
| A | ILE160 |
| B | ARG141 |
| B | PHE164 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 404 |
| Chain | Residue |
| B | ILE55 |
| B | THR56 |
| B | ASP77 |
| B | TYR78 |
| B | ILE79 |
| B | ASP80 |
| B | HOH615 |
Functional Information from PROSITE/UniProt
| site_id | PS00671 |
| Number of Residues | 17 |
| Details | D_2_HYDROXYACID_DH_3 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. MKpDaVLINtCRGnLID |
| Chain | Residue | Details |
| A | MET218-ASP234 | |
