6P26

Escherichia coli tRNA synthetase in complex with compound 1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0004826	molecular_function	phenylalanine-tRNA ligase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006412	biological_process	translation
A	0006432	biological_process	phenylalanyl-tRNA aminoacylation
A	0009328	cellular_component	phenylalanine-tRNA ligase complex
A	0043039	biological_process	tRNA aminoacylation
A	0046872	molecular_function	metal ion binding
B	0000049	molecular_function	tRNA binding
B	0000287	molecular_function	magnesium ion binding
B	0003723	molecular_function	RNA binding
B	0004812	molecular_function	aminoacyl-tRNA ligase activity
B	0004826	molecular_function	phenylalanine-tRNA ligase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006412	biological_process	translation
B	0006432	biological_process	phenylalanyl-tRNA aminoacylation
B	0009328	cellular_component	phenylalanine-tRNA ligase complex
B	0016020	cellular_component	membrane
B	0042802	molecular_function	identical protein binding
B	0046872	molecular_function	metal ion binding
C	0000049	molecular_function	tRNA binding
C	0000166	molecular_function	nucleotide binding
C	0000287	molecular_function	magnesium ion binding
C	0004812	molecular_function	aminoacyl-tRNA ligase activity
C	0004826	molecular_function	phenylalanine-tRNA ligase activity
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006412	biological_process	translation
C	0006432	biological_process	phenylalanyl-tRNA aminoacylation
C	0009328	cellular_component	phenylalanine-tRNA ligase complex
C	0043039	biological_process	tRNA aminoacylation
C	0046872	molecular_function	metal ion binding
D	0000049	molecular_function	tRNA binding
D	0000287	molecular_function	magnesium ion binding
D	0003723	molecular_function	RNA binding
D	0004812	molecular_function	aminoacyl-tRNA ligase activity
D	0004826	molecular_function	phenylalanine-tRNA ligase activity
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006412	biological_process	translation
D	0006432	biological_process	phenylalanyl-tRNA aminoacylation
D	0009328	cellular_component	phenylalanine-tRNA ligase complex
D	0016020	cellular_component	membrane
D	0042802	molecular_function	identical protein binding
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue NO4 A 401

Chain	Residue
A	GLN169
A	GLN174
A	GLU210
A	PHE248
A	PHE250
A	GLY271
A	CYS272
A	PHE295

---

site_id	AC2
Number of Residues	9
Details	binding site for residue NO4 C 401

Chain	Residue
C	GLN169
C	GLN174
C	GLU210
C	PHE250
C	GLY271
C	CYS272
C	VAL279
C	ALA294
C	LEU143

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
B	ASP454
B	ASP460
B	GLU463
B	GLU464
D	ASP454
D	ASP460
D	GLU463
D	GLU464

---