Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6P1N

Pre-catalytic ternary complex of human DNA Polymerase Mu with 1-nt gapped substrate containing template 8OG and bound incoming dAMPNPP

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0003887molecular_functionDNA-directed DNA polymerase activity
A0005634cellular_componentnucleus
A0006281biological_processDNA repair
A0016779molecular_functionnucleotidyltransferase activity
A0034061molecular_functionDNA polymerase activity
Functional Information from PDB Data
site_idAC1
Number of Residues26
Detailsbinding site for residue DZ4 A 501
ChainResidue
AGLY319
ATRP434
ATHR435
AGLY436
ALYS438
AMG502
AMG503
AHOH658
AHOH672
AHOH685
AHOH712
AGLY320
AHOH734
AHOH740
AHOH762
AHOH778
PDA4
PHOH102
T8OG5
AARG323
ALYS325
AGLY328
AHIS329
AASP330
AASP332
AGLY433

site_idAC2
Number of Residues7
Detailsbinding site for residue MG A 502
ChainResidue
AASP330
AASP332
AASP418
ADZ4501
AMG503
PDA4
PHOH102

site_idAC3
Number of Residues5
Detailsbinding site for residue MG A 503
ChainResidue
AASP330
AASP332
ADZ4501
AMG502
AHOH712

site_idAC4
Number of Residues6
Detailsbinding site for residue NA A 504
ChainResidue
ATHR241
AILE243
AVAL246
PDT3
PHOH111
PHOH114

site_idAC5
Number of Residues2
Detailsbinding site for residue CL A 505
ChainResidue
ASER458
TDA7

site_idAC6
Number of Residues4
Detailsbinding site for residue CL A 506
ChainResidue
ASER172
AGLY174
AARG175
AEDO509

site_idAC7
Number of Residues5
Detailsbinding site for residue EDO A 507
ChainResidue
ATHR194
ATHR314
ATHR336
AHOH647
AHOH709

site_idAC8
Number of Residues5
Detailsbinding site for residue EPE A 508
ChainResidue
ALYS325
ALEU326
AGLN327
AHOH720
AHOH727

site_idAC9
Number of Residues4
Detailsbinding site for residue EDO A 509
ChainResidue
AGLY171
AGLU173
AGLY174
ACL506

Functional Information from PROSITE/UniProt
site_idPS00522
Number of Residues20
DetailsDNA_POLYMERASE_X DNA polymerase family X signature. GGFrRGklqGhDVDFLIthP
ChainResidueDetails
AGLY319-PRO338

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
AASP330
AASP332
AASP418

site_idSWS_FT_FI2
Number of Residues1
DetailsSITE: Responsible for the low discrimination between dNTP and rNTP
ChainResidueDetails
AGLY433

227344

PDB entries from 2024-11-13

PDB statisticsPDBj update infoContact PDBjnumon