Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004743 | molecular_function | pyruvate kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006096 | biological_process | glycolytic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016310 | biological_process | phosphorylation |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030955 | molecular_function | potassium ion binding |
| A | 0032869 | biological_process | cellular response to insulin stimulus |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004743 | molecular_function | pyruvate kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006096 | biological_process | glycolytic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016310 | biological_process | phosphorylation |
| B | 0016740 | molecular_function | transferase activity |
| B | 0030955 | molecular_function | potassium ion binding |
| B | 0032869 | biological_process | cellular response to insulin stimulus |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue ADP A 601 |
| Chain | Residue |
| A | THR51 |
| A | ASN367 |
| A | MG602 |
| A | HOH718 |
| A | HOH760 |
| A | PRO54 |
| A | ARG74 |
| A | ASN76 |
| A | HIS79 |
| A | ARG116 |
| A | SER362 |
| A | GLY363 |
| A | ALA366 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 602 |
| Chain | Residue |
| A | ASP170 |
| A | ADP601 |
| A | HOH760 |
| A | HOH789 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue K A 603 |
| Chain | Residue |
| A | ASN76 |
| A | SER78 |
| A | ASP109 |
| A | THR110 |
| A | SER236 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 604 |
| Chain | Residue |
| A | THR103 |
| A | LYS464 |
| A | THR471 |
| site_id | AC5 |
| Number of Residues | 17 |
| Details | binding site for residue ADP B 601 |
| Chain | Residue |
| B | THR51 |
| B | ILE52 |
| B | PRO54 |
| B | ARG74 |
| B | ASN76 |
| B | HIS79 |
| B | GLY80 |
| B | ARG116 |
| B | SER362 |
| B | ALA366 |
| B | ASN367 |
| B | MG602 |
| B | HOH709 |
| B | HOH744 |
| B | HOH746 |
| B | HOH774 |
| B | HOH775 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 602 |
| Chain | Residue |
| B | ASP170 |
| B | ADP601 |
| B | HOH709 |
| B | HOH774 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue K B 603 |
| Chain | Residue |
| B | ASN76 |
| B | SER78 |
| B | ASP109 |
| B | THR110 |
| B | SER236 |
| B | HOH780 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 604 |
| Chain | Residue |
| B | THR103 |
| B | LYS464 |
| B | THR471 |
Functional Information from PROSITE/UniProt
| site_id | PS00110 |
| Number of Residues | 13 |
| Details | PYRUVATE_KINASE Pyruvate kinase active site signature. IkIISKIENlEGV |
| Chain | Residue | Details |
| A | ILE265-VAL277 | |
