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6OZU

Crystal structure of the MIF4G domain of Trypanosoma cruzi translation initiation factor EIF4G5

Functional Information from GO Data
ChainGOidnamespacecontents
A0003723molecular_functionRNA binding
A0003743molecular_functiontranslation initiation factor activity
B0003723molecular_functionRNA binding
B0003743molecular_functiontranslation initiation factor activity
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue SO4 A 401
ChainResidue
ALYS166
ASER211
AASN214
AHOH511

site_idAC2
Number of Residues6
Detailsbinding site for residue SO4 A 402
ChainResidue
BGLU261
AARG308
AGLN353
AARG354
AARG355
AHOH501

site_idAC3
Number of Residues3
Detailsbinding site for residue SO4 A 403
ChainResidue
AARG308
APHE309
AARG355

site_idAC4
Number of Residues7
Detailsbinding site for residue SO4 A 404
ChainResidue
ALEU172
APRO173
AILE174
AARG175
AGLN176
AHOH504
BGLN176

site_idAC5
Number of Residues4
Detailsbinding site for residue SO4 A 405
ChainResidue
AGLU249
AGLY302
ATHR303
AARG307

site_idAC6
Number of Residues2
Detailsbinding site for residue SO4 A 406
ChainResidue
AARG264
AARG307

site_idAC7
Number of Residues6
Detailsbinding site for residue SO4 A 407
ChainResidue
APRO196
ALYS272
AMET348
AGLN357
ALEU361
BGLU365

site_idAC8
Number of Residues6
Detailsbinding site for residue GOL A 408
ChainResidue
AARG224
APHE225
AASN228
AARG232
BARG224
BGOL407

site_idAC9
Number of Residues6
Detailsbinding site for residue GOL A 409
ChainResidue
AILE275
AASN276
AHIS317
AASN320
ATHR324
BASN362

site_idAD1
Number of Residues4
Detailsbinding site for residue GOL A 410
ChainResidue
AHIS376
AHIS378
BLYS166
BLYS207

site_idAD2
Number of Residues3
Detailsbinding site for residue SO4 B 401
ChainResidue
AARG250
BARG156
BASN161

site_idAD3
Number of Residues6
Detailsbinding site for residue SO4 B 402
ChainResidue
AGLU261
BARG308
BGLN353
BARG354
BARG355
BHOH503

site_idAD4
Number of Residues2
Detailsbinding site for residue SO4 B 403
ChainResidue
BGLU289
BLYS339

site_idAD5
Number of Residues6
Detailsbinding site for residue SO4 B 404
ChainResidue
AGLN176
BLEU172
BPRO173
BILE174
BARG175
BGLN176

site_idAD6
Number of Residues3
Detailsbinding site for residue SO4 B 405
ChainResidue
BLYS166
BSER211
BASN214

site_idAD7
Number of Residues2
Detailsbinding site for residue SO4 B 406
ChainResidue
BGLU218
BARG227

site_idAD8
Number of Residues8
Detailsbinding site for residue GOL B 407
ChainResidue
AARG224
AGOL408
BARG224
BPHE225
BASN228
BARG232
BHOH507
BHOH508

site_idAD9
Number of Residues4
Detailsbinding site for residue GOL B 408
ChainResidue
BARG307
BARG308
BPHE309
BARG355

site_idAE1
Number of Residues5
Detailsbinding site for residue GOL B 409
ChainResidue
BGLN245
BGLU249
BTRP298
BGLY302
BTHR303

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PDB entries from 2024-10-30

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