6OZ8

Crystal structure of Mtb aspartate decarboxylase in active form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004068	molecular_function	aspartate 1-decarboxylase activity
A	0006523	biological_process	alanine biosynthetic process
B	0004068	molecular_function	aspartate 1-decarboxylase activity
B	0006523	biological_process	alanine biosynthetic process
C	0004068	molecular_function	aspartate 1-decarboxylase activity
C	0006523	biological_process	alanine biosynthetic process
D	0004068	molecular_function	aspartate 1-decarboxylase activity
D	0006523	biological_process	alanine biosynthetic process
E	0004068	molecular_function	aspartate 1-decarboxylase activity
E	0006523	biological_process	alanine biosynthetic process
F	0004068	molecular_function	aspartate 1-decarboxylase activity
F	0006523	biological_process	alanine biosynthetic process
G	0004068	molecular_function	aspartate 1-decarboxylase activity
G	0006523	biological_process	alanine biosynthetic process
H	0004068	molecular_function	aspartate 1-decarboxylase activity
H	0006523	biological_process	alanine biosynthetic process
I	0004068	molecular_function	aspartate 1-decarboxylase activity
I	0006523	biological_process	alanine biosynthetic process
J	0004068	molecular_function	aspartate 1-decarboxylase activity
J	0006523	biological_process	alanine biosynthetic process
K	0004068	molecular_function	aspartate 1-decarboxylase activity
K	0006523	biological_process	alanine biosynthetic process
L	0004068	molecular_function	aspartate 1-decarboxylase activity
L	0006523	biological_process	alanine biosynthetic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: Schiff-base intermediate with substrate; via pyruvic acid => ECO:0000255|HAMAP-Rule:MF_00446

Chain	Residue	Details
B	PYR25
D	PYR25
J	PYR25
F	PYR25
L	PYR25
H	PYR25

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site_id	SWS_FT_FI2
Number of Residues	6
Details	ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_00446

Chain	Residue	Details
B	TYR58
D	TYR58
J	TYR58
F	TYR58
L	TYR58
H	TYR58

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site_id	SWS_FT_FI3
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00446

Chain	Residue	Details
B	THR57
L	GLY73
H	THR57
H	GLY73
B	GLY73
D	THR57
D	GLY73
J	THR57
J	GLY73
F	THR57
F	GLY73
L	THR57

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site_id	SWS_FT_FI4
Number of Residues	6
Details	MOD_RES: Pyruvic acid (Ser) => ECO:0000255|HAMAP-Rule:MF_00446

Chain	Residue	Details
B	PYR25
D	PYR25
J	PYR25
F	PYR25
L	PYR25
H	PYR25

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