Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000162 | biological_process | L-tryptophan biosynthetic process |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004834 | molecular_function | tryptophan synthase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006568 | biological_process | L-tryptophan metabolic process |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 401 |
| Chain | Residue |
| A | VAL126 |
| A | LEU127 |
| A | VAL128 |
| A | ILE151 |
| A | HOH576 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | GLY61 |
| A | PRO62 |
| A | THR63 |
| A | HOH556 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 403 |
| Chain | Residue |
| A | ALA246 |
| A | SER247 |
| A | PRO248 |
| A | LYS249 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 404 |
| Chain | Residue |
| A | ARG14 |
| A | LYS91 |
| A | HIS92 |
| A | PRO93 |
| A | HOH510 |
| A | HOH517 |
| A | HOH568 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 405 |
| Chain | Residue |
| A | GLY29 |
| A | ILE30 |
| A | GLU31 |
| A | GLN32 |
| A | LYS35 |
| A | HOH520 |
| A | HOH555 |
| A | HOH581 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 406 |
| Chain | Residue |
| A | GLN141 |
| A | ARG145 |
| A | ARG225 |
| A | HOH506 |
| A | HOH623 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 A 407 |
| Chain | Residue |
| A | MET1 |
| A | GLU2 |
| A | ARG3 |
| A | TYR4 |
| A | GLU5 |
| A | HOH501 |
| A | HOH545 |
| A | HOH578 |
| A | HOH677 |
Functional Information from PROSITE/UniProt
| site_id | PS00167 |
| Number of Residues | 14 |
| Details | TRP_SYNTHASE_ALPHA Tryptophan synthase alpha chain signature. LELGvPFSDPLADG |
| Chain | Residue | Details |
| A | LEU48-GLY61 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor"} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 383 |
| Chain | Residue | Details |
| A | GLU49 | hydrogen bond acceptor, proton acceptor, proton donor |
| A | ASP60 | hydrogen bond acceptor |
| A | TYR175 | hydrogen bond donor |
