6OSS
Crystal Structure of the Acyl-Carrier-Protein UDP-N-Acetylglucosamine O-Acyltransferase LpxA from Proteus mirabilis
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005737 | cellular_component | cytoplasm |
A | 0008610 | biological_process | lipid biosynthetic process |
A | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
A | 0009245 | biological_process | lipid A biosynthetic process |
A | 0016740 | molecular_function | transferase activity |
A | 0016746 | molecular_function | acyltransferase activity |
A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
B | 0005737 | cellular_component | cytoplasm |
B | 0008610 | biological_process | lipid biosynthetic process |
B | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
B | 0009245 | biological_process | lipid A biosynthetic process |
B | 0016740 | molecular_function | transferase activity |
B | 0016746 | molecular_function | acyltransferase activity |
B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
C | 0005737 | cellular_component | cytoplasm |
C | 0008610 | biological_process | lipid biosynthetic process |
C | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
C | 0009245 | biological_process | lipid A biosynthetic process |
C | 0016740 | molecular_function | transferase activity |
C | 0016746 | molecular_function | acyltransferase activity |
C | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | binding site for residue SO4 A 301 |
Chain | Residue |
A | HIS35 |
A | ASN51 |
A | GLY52 |
A | ARG100 |
A | HOH404 |
A | HOH410 |
site_id | AC2 |
Number of Residues | 5 |
Details | binding site for residue SO4 A 303 |
Chain | Residue |
C | HIS160 |
C | HIS191 |
A | GLY172 |
A | GLY173 |
A | GLN188 |
site_id | AC3 |
Number of Residues | 5 |
Details | binding site for residue SO4 B 301 |
Chain | Residue |
A | HIS160 |
A | HIS191 |
B | GLY172 |
B | GLY173 |
B | GLN188 |
site_id | AC4 |
Number of Residues | 3 |
Details | binding site for residue SO4 B 302 |
Chain | Residue |
B | ASN51 |
B | GLY52 |
B | HOH404 |
site_id | AC5 |
Number of Residues | 5 |
Details | binding site for residue SO4 C 301 |
Chain | Residue |
B | HIS160 |
B | HIS191 |
C | GLY172 |
C | GLY173 |
C | GLN188 |
site_id | AC6 |
Number of Residues | 5 |
Details | binding site for residue SO4 C 302 |
Chain | Residue |
C | ASN51 |
C | GLY52 |
C | ARG100 |
C | HOH403 |
C | HOH407 |
site_id | AC7 |
Number of Residues | 17 |
Details | binding site for Di-peptide PO3 A 302 and CYS B 174 |
Chain | Residue |
A | GLY155 |
A | MET156 |
A | SER157 |
A | GLY172 |
A | GLY173 |
A | SER175 |
A | ASN190 |
B | ASN51 |
B | GLY52 |
B | GLY155 |
B | MET156 |
B | SER157 |
B | GLY172 |
B | GLY173 |
B | SER175 |
B | HOH404 |
C | CYS174 |
site_id | AC8 |
Number of Residues | 20 |
Details | binding site for Di-peptide PO3 A 302 and CYS C 174 |
Chain | Residue |
A | GLY155 |
A | MET156 |
A | SER157 |
A | GLY172 |
A | GLY173 |
A | SER175 |
A | ASN190 |
B | MET156 |
B | CYS174 |
C | ASN51 |
C | GLY52 |
C | ARG100 |
C | GLY155 |
C | MET156 |
C | SER157 |
C | GLY172 |
C | GLY173 |
C | SER175 |
C | HOH403 |
C | HOH407 |
Functional Information from PROSITE/UniProt
site_id | PS00101 |
Number of Residues | 29 |
Details | HEXAPEP_TRANSFERASES Hexapeptide-repeat containing-transferases signature. IGanVrIgpfCvIGshVeIGegTdIkshV |
Chain | Residue | Details |
A | ILE20-VAL48 | |
A | ILE153-VAL181 |