6OSS
Crystal Structure of the Acyl-Carrier-Protein UDP-N-Acetylglucosamine O-Acyltransferase LpxA from Proteus mirabilis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0008610 | biological_process | lipid biosynthetic process |
| A | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| A | 0009245 | biological_process | lipid A biosynthetic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0008610 | biological_process | lipid biosynthetic process |
| B | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| B | 0009245 | biological_process | lipid A biosynthetic process |
| B | 0016020 | cellular_component | membrane |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006629 | biological_process | lipid metabolic process |
| C | 0008610 | biological_process | lipid biosynthetic process |
| C | 0008780 | molecular_function | acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity |
| C | 0009245 | biological_process | lipid A biosynthetic process |
| C | 0016020 | cellular_component | membrane |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016746 | molecular_function | acyltransferase activity |
| C | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | HIS35 |
| A | ASN51 |
| A | GLY52 |
| A | ARG100 |
| A | HOH404 |
| A | HOH410 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| C | HIS160 |
| C | HIS191 |
| A | GLY172 |
| A | GLY173 |
| A | GLN188 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 302 |
| Chain | Residue |
| A | HIS160 |
| A | HIS191 |
| B | GLY172 |
| B | GLY173 |
| B | GLN188 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 303 |
| Chain | Residue |
| B | ASN51 |
| B | GLY52 |
| B | HOH404 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 C 301 |
| Chain | Residue |
| B | HIS160 |
| B | HIS191 |
| C | GLY172 |
| C | GLY173 |
| C | GLN188 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 C 302 |
| Chain | Residue |
| C | ASN51 |
| C | GLY52 |
| C | ARG100 |
| C | HOH403 |
| C | HOH407 |
| site_id | AC7 |
| Number of Residues | 17 |
| Details | binding site for Di-peptide PO3 A 302 and CYS B 174 |
| Chain | Residue |
| A | GLY155 |
| A | MET156 |
| A | SER157 |
| A | GLY172 |
| A | GLY173 |
| A | SER175 |
| A | ASN190 |
| B | ASN51 |
| B | GLY52 |
| B | GLY155 |
| B | MET156 |
| B | SER157 |
| B | GLY172 |
| B | GLY173 |
| B | SER175 |
| B | HOH404 |
| C | CYS174 |
| site_id | AC8 |
| Number of Residues | 20 |
| Details | binding site for Di-peptide PO3 A 302 and CYS C 174 |
| Chain | Residue |
| A | GLY155 |
| A | MET156 |
| A | SER157 |
| A | GLY172 |
| A | GLY173 |
| A | SER175 |
| A | ASN190 |
| B | MET156 |
| B | CYS174 |
| C | ASN51 |
| C | GLY52 |
| C | ARG100 |
| C | GLY155 |
| C | MET156 |
| C | SER157 |
| C | GLY172 |
| C | GLY173 |
| C | SER175 |
| C | HOH403 |
| C | HOH407 |
Functional Information from PROSITE/UniProt
| site_id | PS00101 |
| Number of Residues | 29 |
| Details | HEXAPEP_TRANSFERASES Hexapeptide-repeat containing-transferases signature. IGanVrIgpfCvIGshVeIGegTdIkshV |
| Chain | Residue | Details |
| A | ILE20-VAL48 | |
| A | ILE153-VAL181 |
