Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000162 | biological_process | tryptophan biosynthetic process |
| A | 0004834 | molecular_function | tryptophan synthase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006568 | biological_process | tryptophan metabolic process |
| A | 0016829 | molecular_function | lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | GLY29 |
| A | ILE30 |
| A | GLU31 |
| A | GLN32 |
| A | LYS35 |
| A | HOH423 |
| A | HOH436 |
| A | HOH507 |
| A | HOH581 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | PHE22 |
| A | LEU58 |
| A | ILE64 |
| A | LEU100 |
| A | GLY234 |
| A | HOH409 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | ARG14 |
| A | LYS91 |
| A | HIS92 |
| A | PRO93 |
| A | HOH405 |
| A | HOH407 |
| A | HOH431 |
| A | HOH560 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | GLY61 |
| A | PRO62 |
| A | THR63 |
| A | HOH465 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 305 |
| Chain | Residue |
| A | SER247 |
| A | PRO248 |
| A | LYS249 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 306 |
| Chain | Residue |
| A | GLN141 |
| A | ARG145 |
| A | ARG225 |
| A | HOH434 |
| A | HOH443 |
| A | HOH519 |
| A | HOH583 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 307 |
| Chain | Residue |
| A | ASP160 |
| A | HIS195 |
| A | LYS199 |
| A | GLN250 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 308 |
| Chain | Residue |
| A | GLU2 |
| A | ARG3 |
| A | TYR4 |
| A | GLU5 |
| A | CL313 |
| A | HOH439 |
| A | HOH453 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 309 |
| Chain | Residue |
| A | ASP159 |
| A | ASP160 |
| A | HOH632 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 311 |
| Chain | Residue |
| A | SER178 |
| A | HOH518 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 312 |
| Chain | Residue |
| A | SER235 |
| A | HOH496 |
| A | HOH505 |
| A | HOH609 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 313 |
| Chain | Residue |
| A | MET1 |
| A | GLU2 |
| A | ARG3 |
| A | ASP124 |
| A | SO4308 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 314 |
| Chain | Residue |
| A | ARG171 |
| A | GLY172 |
| A | HOH453 |
| A | HOH659 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 315 |
| Chain | Residue |
| A | VAL126 |
| A | LEU127 |
| A | VAL128 |
| A | ILE151 |
| A | PHE152 |
| A | HOH449 |
Functional Information from PROSITE/UniProt
| site_id | PS00167 |
| Number of Residues | 14 |
| Details | TRP_SYNTHASE_ALPHA Tryptophan synthase alpha chain signature. LELGvPFSDPLADG |
| Chain | Residue | Details |
| A | LEU48-GLY61 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor |
| Chain | Residue | Details |
| A | GLU49 | |
| A | ASP60 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 383 |
| Chain | Residue | Details |
| A | GLU49 | hydrogen bond acceptor, proton acceptor, proton donor |
| A | ASP60 | hydrogen bond acceptor |
| A | TYR175 | hydrogen bond donor |
