6OP8
S. pombe Ubc7/U7BR complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000151 | cellular_component | ubiquitin ligase complex |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000209 | biological_process | protein polyubiquitination |
| A | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005829 | cellular_component | cytosol |
| A | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
| A | 0016567 | biological_process | protein ubiquitination |
| A | 0016740 | molecular_function | transferase activity |
| A | 0036503 | biological_process | ERAD pathway |
| A | 0061631 | molecular_function | ubiquitin conjugating enzyme activity |
| A | 0061650 | molecular_function | ubiquitin-like protein conjugating enzyme activity |
| A | 0180027 | biological_process | inner nuclear membrane-associated protein degradation pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 201 |
| Chain | Residue |
| A | HOH312 |
| A | HOH316 |
| A | HOH414 |
| A | HOH446 |
| B | HOH335 |
| B | HOH346 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 202 |
| Chain | Residue |
| A | HOH303 |
| A | HOH338 |
| B | SER180 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 203 |
| Chain | Residue |
| A | ASP34 |
| A | PHE35 |
| A | PHE36 |
| B | GLN212 |
Functional Information from PROSITE/UniProt
| site_id | PS00183 |
| Number of Residues | 16 |
| Details | UBC_1 Ubiquitin-conjugating (UBC) active site signature. FHPNVykd.GtVCIsiL |
| Chain | Residue | Details |
| A | PHE79-LEU94 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 160 |
| Details | Domain: {"description":"UBC core","evidences":[{"source":"PROSITE-ProRule","id":"PRU00388","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Glycyl thioester intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00388","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10133","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl cysteine thioester (Cys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"Q02159","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 11 |
| Details | Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
