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6ON4

Crystal structure of the GntR-type sialoregulator NanR from Escherichia coli, in complex with sialic acid

Functional Information from GO Data
ChainGOidnamespacecontents
A0000987molecular_functioncis-regulatory region sequence-specific DNA binding
A0001046molecular_functioncore promoter sequence-specific DNA binding
A0001217molecular_functionDNA-binding transcription repressor activity
A0003677molecular_functionDNA binding
A0003700molecular_functionDNA-binding transcription factor activity
A0006351biological_processDNA-templated transcription
A0006355biological_processregulation of DNA-templated transcription
A0031334biological_processpositive regulation of protein-containing complex assembly
A0042803molecular_functionprotein homodimerization activity
A0045892biological_processnegative regulation of DNA-templated transcription
A2000143biological_processnegative regulation of DNA-templated transcription initiation
B0000987molecular_functioncis-regulatory region sequence-specific DNA binding
B0001046molecular_functioncore promoter sequence-specific DNA binding
B0001217molecular_functionDNA-binding transcription repressor activity
B0003677molecular_functionDNA binding
B0003700molecular_functionDNA-binding transcription factor activity
B0006351biological_processDNA-templated transcription
B0006355biological_processregulation of DNA-templated transcription
B0031334biological_processpositive regulation of protein-containing complex assembly
B0042803molecular_functionprotein homodimerization activity
B0045892biological_processnegative regulation of DNA-templated transcription
B2000143biological_processnegative regulation of DNA-templated transcription initiation
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues68
DetailsDomain: {"description":"HTH gntR-type","evidences":[{"source":"HAMAP-Rule","id":"MF_01236","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues38
DetailsDNA binding: {"description":"H-T-H motif","evidences":[{"source":"HAMAP-Rule","id":"MF_01236","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

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PDB entries from 2025-12-17

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