6OHT

Structure of EBP and U18666A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000247	molecular_function	C-8 sterol isomerase activity
A	0004769	molecular_function	steroid Delta-isomerase activity
A	0005515	molecular_function	protein binding
A	0005635	cellular_component	nuclear envelope
A	0005783	cellular_component	endoplasmic reticulum
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0006629	biological_process	lipid metabolic process
A	0006694	biological_process	steroid biosynthetic process
A	0006695	biological_process	cholesterol biosynthetic process
A	0008202	biological_process	steroid metabolic process
A	0008203	biological_process	cholesterol metabolic process
A	0016020	cellular_component	membrane
A	0016125	biological_process	sterol metabolic process
A	0016126	biological_process	sterol biosynthetic process
A	0016787	molecular_function	hydrolase activity
A	0016853	molecular_function	isomerase activity
A	0016863	molecular_function	intramolecular oxidoreductase activity, transposing C=C bonds
A	0031410	cellular_component	cytoplasmic vesicle
A	0031965	cellular_component	nuclear membrane
A	0033489	biological_process	cholesterol biosynthetic process via desmosterol
A	0033490	biological_process	cholesterol biosynthetic process via lathosterol
A	0033963	molecular_function	cholesterol-5,6-oxide hydrolase activity
A	0042802	molecular_function	identical protein binding
A	0043931	biological_process	ossification involved in bone maturation
A	0047750	molecular_function	cholestenol delta-isomerase activity
B	0000247	molecular_function	C-8 sterol isomerase activity
B	0004769	molecular_function	steroid Delta-isomerase activity
B	0005515	molecular_function	protein binding
B	0005635	cellular_component	nuclear envelope
B	0005783	cellular_component	endoplasmic reticulum
B	0005789	cellular_component	endoplasmic reticulum membrane
B	0006629	biological_process	lipid metabolic process
B	0006694	biological_process	steroid biosynthetic process
B	0006695	biological_process	cholesterol biosynthetic process
B	0008202	biological_process	steroid metabolic process
B	0008203	biological_process	cholesterol metabolic process
B	0016020	cellular_component	membrane
B	0016125	biological_process	sterol metabolic process
B	0016126	biological_process	sterol biosynthetic process
B	0016787	molecular_function	hydrolase activity
B	0016853	molecular_function	isomerase activity
B	0016863	molecular_function	intramolecular oxidoreductase activity, transposing C=C bonds
B	0031410	cellular_component	cytoplasmic vesicle
B	0031965	cellular_component	nuclear membrane
B	0033489	biological_process	cholesterol biosynthetic process via desmosterol
B	0033490	biological_process	cholesterol biosynthetic process via lathosterol
B	0033963	molecular_function	cholesterol-5,6-oxide hydrolase activity
B	0042802	molecular_function	identical protein binding
B	0043931	biological_process	ossification involved in bone maturation
B	0047750	molecular_function	cholestenol delta-isomerase activity
C	0000247	molecular_function	C-8 sterol isomerase activity
C	0004769	molecular_function	steroid Delta-isomerase activity
C	0005515	molecular_function	protein binding
C	0005635	cellular_component	nuclear envelope
C	0005783	cellular_component	endoplasmic reticulum
C	0005789	cellular_component	endoplasmic reticulum membrane
C	0006629	biological_process	lipid metabolic process
C	0006694	biological_process	steroid biosynthetic process
C	0006695	biological_process	cholesterol biosynthetic process
C	0008202	biological_process	steroid metabolic process
C	0008203	biological_process	cholesterol metabolic process
C	0016020	cellular_component	membrane
C	0016125	biological_process	sterol metabolic process
C	0016126	biological_process	sterol biosynthetic process
C	0016787	molecular_function	hydrolase activity
C	0016853	molecular_function	isomerase activity
C	0016863	molecular_function	intramolecular oxidoreductase activity, transposing C=C bonds
C	0031410	cellular_component	cytoplasmic vesicle
C	0031965	cellular_component	nuclear membrane
C	0033489	biological_process	cholesterol biosynthetic process via desmosterol
C	0033490	biological_process	cholesterol biosynthetic process via lathosterol
C	0033963	molecular_function	cholesterol-5,6-oxide hydrolase activity
C	0042802	molecular_function	identical protein binding
C	0043931	biological_process	ossification involved in bone maturation
C	0047750	molecular_function	cholestenol delta-isomerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue MKM A 301

Chain	Residue
A	ILE31
A	TYR188
A	MSE192
A	ASN193
A	TRP196
A	LEU32
A	GLU80
A	LEU100
A	TYR104
A	MSE121
A	ASP162
A	TYR165
A	PHE187

---

site_id	AC2
Number of Residues	10
Details	binding site for residue MKM B 301

Chain	Residue
B	ILE31
B	LEU35
B	GLU80
B	LEU100
B	MSE121
B	ASP162
B	TYR188
B	MSE192
B	ASN193
B	TRP196

---

site_id	AC3
Number of Residues	13
Details	binding site for residue MKM C 301

Chain	Residue
C	ILE31
C	LEU35
C	GLU80
C	LEU100
C	GLU103
C	TYR104
C	MSE121
C	ASP162
C	TYR165
C	TYR188
C	MSE192
C	ASN193
C	TRP196

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	60
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---