6OH3
X-ray crystal structure of the mouse CMP-sialic acid transporter in complex with CMP-sialic acid, by lipidic cubic phase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000139 | cellular_component | Golgi membrane |
| A | 0005456 | molecular_function | CMP-N-acetylneuraminate transmembrane transporter activity |
| A | 0006054 | biological_process | N-acetylneuraminate metabolic process |
| A | 0015165 | molecular_function | pyrimidine nucleotide-sugar transmembrane transporter activity |
| A | 0015297 | molecular_function | antiporter activity |
| A | 0015782 | biological_process | CMP-N-acetylneuraminate transmembrane transport |
| A | 0016020 | cellular_component | membrane |
| A | 0090481 | biological_process | pyrimidine nucleotide-sugar transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue NCC A 401 |
| Chain | Residue |
| A | ALA24 |
| A | SER188 |
| A | PHE195 |
| A | ASN210 |
| A | TYR214 |
| A | GLY257 |
| A | THR260 |
| A | SER261 |
| A | LYS272 |
| A | HOH501 |
| A | TYR27 |
| A | LYS55 |
| A | TYR98 |
| A | GLN101 |
| A | ASN102 |
| A | TYR117 |
| A | TYR121 |
| A | LYS124 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 188 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"30985278","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 40 |
| Details | Topological domain: {"description":"Lumenal","evidences":[{"source":"PubMed","id":"30985278","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 45 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"30985278","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 15 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30985278","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6OH2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OH3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
