Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 1001 |
| Chain | Residue |
| A | TYR287 |
| A | ARG451 |
| A | TRP458 |
| A | LEU478 |
| A | GLU481 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue PO4 A 1002 |
| Chain | Residue |
| A | GLN399 |
| A | ARG402 |
| A | HOH1129 |
| A | LYS34 |
| A | TYR49 |
| A | PRO50 |
| A | HIS51 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 1003 |
| Chain | Residue |
| A | HIS267 |
| A | LEU268 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 1004 |
| Chain | Residue |
| A | GLU196 |
| A | PRO197 |
| A | ILE198 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 1001 |
| Chain | Residue |
| B | TYR287 |
| B | ARG451 |
| B | TRP458 |
| B | LEU478 |
| B | GLU481 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue PO4 B 1002 |
| Chain | Residue |
| B | LYS34 |
| B | TYR49 |
| B | PRO50 |
| B | HIS51 |
| B | GLN399 |
| B | ARG402 |
Functional Information from PROSITE/UniProt
| site_id | PS00143 |
| Number of Residues | 24 |
| Details | INSULINASE Insulinase family, zinc-binding region signature. GslqeednelGvAHFVEHMmFnGT |
| Chain | Residue | Details |
| A | GLY67-THR90 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10096","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10096","evidenceCode":"ECO:0000255"}]} |
