6OF8
Structure of Thr354Asn, Glu355Gln, Thr412Asn, Ile414Met, Ile464His, and Phe467Met mutant human CamKII-alpha hub domain
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004683 | molecular_function | calcium/calmodulin-dependent protein kinase activity |
| A | 0005516 | molecular_function | calmodulin binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004683 | molecular_function | calcium/calmodulin-dependent protein kinase activity |
| B | 0005516 | molecular_function | calmodulin binding |
| B | 0006468 | biological_process | protein phosphorylation |
| C | 0004683 | molecular_function | calcium/calmodulin-dependent protein kinase activity |
| C | 0005516 | molecular_function | calmodulin binding |
| C | 0006468 | biological_process | protein phosphorylation |
| D | 0004683 | molecular_function | calcium/calmodulin-dependent protein kinase activity |
| D | 0005516 | molecular_function | calmodulin binding |
| D | 0006468 | biological_process | protein phosphorylation |
| E | 0004683 | molecular_function | calcium/calmodulin-dependent protein kinase activity |
| E | 0005516 | molecular_function | calmodulin binding |
| E | 0006468 | biological_process | protein phosphorylation |
| F | 0004683 | molecular_function | calcium/calmodulin-dependent protein kinase activity |
| F | 0005516 | molecular_function | calmodulin binding |
| F | 0006468 | biological_process | protein phosphorylation |
| G | 0004683 | molecular_function | calcium/calmodulin-dependent protein kinase activity |
| G | 0005516 | molecular_function | calmodulin binding |
| G | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue K F 501 |
| Chain | Residue |
| D | GLN348 |
| F | THR370 |
| F | LYS371 |
| F | CYS373 |
| F | GLN463 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue K F 502 |
| Chain | Residue |
| F | MET377 |
| F | ALA379 |
| F | VAL389 |
| F | GLY391 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue GOL C 501 |
| Chain | Residue |
| C | GLN448 |
| D | LEU385 |
| D | GLY386 |
| D | ASN387 |
| E | LEU385 |
| E | GLY386 |
| E | ASN387 |
| F | GLN448 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue GOL E 501 |
| Chain | Residue |
| E | GLN448 |
| F | LEU385 |
| F | ASN387 |
| G | GLN448 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue K E 502 |
| Chain | Residue |
| E | THR370 |
| E | LYS371 |
| E | CYS373 |
| E | GLN463 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 501 |
| Chain | Residue |
| A | LEU385 |
| A | GLY386 |
| A | ASN387 |
| B | ILE432 |
| B | GLN448 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue K A 502 |
| Chain | Residue |
| A | THR370 |
| A | LYS371 |
| A | CYS373 |
| A | GLN463 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue K D 501 |
| Chain | Residue |
| D | THR370 |
| D | LYS371 |
| D | CYS373 |
| D | GLN463 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P11798","evidenceCode":"ECO:0000250"}]} |
