6OD8
Crystal structure of a putative aspartyl-tRNA synthetase from Leishmania major Friedlin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004815 | molecular_function | aspartate-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006412 | biological_process | translation |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006422 | biological_process | aspartyl-tRNA aminoacylation |
| A | 0016874 | molecular_function | ligase activity |
| A | 0017101 | cellular_component | aminoacyl-tRNA synthetase multienzyme complex |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003723 | molecular_function | RNA binding |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004815 | molecular_function | aspartate-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006412 | biological_process | translation |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006422 | biological_process | aspartyl-tRNA aminoacylation |
| B | 0016874 | molecular_function | ligase activity |
| B | 0017101 | cellular_component | aminoacyl-tRNA synthetase multienzyme complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 601 |
| Chain | Residue |
| A | GLU454 |
| A | ARG490 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 602 |
| Chain | Residue |
| A | SER266 |
| A | GLY305 |
| A | ASP307 |
| A | GLY519 |
| A | ILE520 |
| A | HOH712 |
| A | HOH948 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 603 |
| Chain | Residue |
| A | GLN381 |
| A | ARG383 |
| A | ARG393 |
| A | ASN395 |
| A | ASP441 |
| A | HOH804 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 604 |
| Chain | Residue |
| A | MET453 |
| A | GLU454 |
| A | HOH901 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 605 |
| Chain | Residue |
| A | SER266 |
| A | PRO267 |
| A | GLN268 |
| A | LEU269 |
| A | TYR270 |
| A | HOH763 |
| A | HOH805 |
| A | HOH970 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 606 |
| Chain | Residue |
| A | ASP321 |
| A | GLU324 |
| A | SER325 |
| A | HIS385 |
| A | ASN386 |
| A | SER389 |
| A | HOH852 |
| A | HOH973 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 607 |
| Chain | Residue |
| A | GLU332 |
| A | ARG333 |
| A | THR336 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 608 |
| Chain | Residue |
| A | THR405 |
| A | LEU407 |
| A | ASP408 |
| A | LYS410 |
| B | ASP457 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 609 |
| Chain | Residue |
| A | GLY426 |
| A | LYS430 |
| A | ASP436 |
| A | ARG470 |
| A | HOH754 |
| A | HOH837 |
| A | HOH874 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue FMT A 610 |
| Chain | Residue |
| A | ILE501 |
| A | GLU503 |
| A | TYR504 |
| B | PRO550 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 601 |
| Chain | Residue |
| B | GLU454 |
| B | ARG490 |
| B | HOH956 |
| B | HOH996 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 602 |
| Chain | Residue |
| B | ARG290 |
| B | GLY305 |
| B | ASP307 |
| B | GLY519 |
| B | HOH717 |
| site_id | AD4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 603 |
| Chain | Residue |
| B | GLN381 |
| B | ARG383 |
| B | ARG393 |
| B | ILE394 |
| B | ASN395 |
| B | ASP441 |
| B | HOH708 |
| B | HOH780 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 604 |
| Chain | Residue |
| B | MET453 |
| B | GLU454 |
| B | ILE481 |
| B | HOH850 |
| B | HOH917 |
| B | HOH956 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 605 |
| Chain | Residue |
| B | ASP321 |
| B | GLU324 |
| B | SER325 |
| B | ASN386 |
| B | SER389 |
| B | HOH971 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 606 |
| Chain | Residue |
| B | GLU332 |
| B | ARG333 |
| B | THR336 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 607 |
| Chain | Residue |
| A | ASP457 |
| B | THR405 |
| B | VAL406 |
| B | LEU407 |
| B | ASP408 |
| B | LYS410 |
| B | HOH969 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 608 |
| Chain | Residue |
| B | GLY426 |
| B | ASP436 |
| B | ARG470 |
| B | HOH768 |
| B | HOH922 |
| B | HOH1000 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue FMT B 609 |
| Chain | Residue |
| B | ILE501 |
| B | GLU503 |
| B | TYR504 |
| B | HOH972 |
| A | PRO550 |
