6OCD

Ricin A chain bound to VHH antibody V6D4

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0017148	biological_process	negative regulation of translation
A	0030598	molecular_function	rRNA N-glycosylase activity
C	0017148	biological_process	negative regulation of translation
C	0030598	molecular_function	rRNA N-glycosylase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue ZN A 301

Chain	Residue
A	GLU102
A	HIS106
A	IMD303

---

site_id	AC2
Number of Residues	2
Details	binding site for residue CL A 302

Chain	Residue
A	ARG114
A	HOH475

---

site_id	AC3
Number of Residues	4
Details	binding site for residue IMD A 303

Chain	Residue
A	GLU102
A	HIS106
A	ZN301
A	HOH411

---

site_id	AC4
Number of Residues	5
Details	binding site for residue EDO A 304

Chain	Residue
A	ASN122
A	TYR123
A	HOH402
A	HOH405
A	HOH459

---

site_id	AC5
Number of Residues	2
Details	binding site for residue ZN C 301

Chain	Residue
C	GLU102
C	HIS106

---

site_id	AC6
Number of Residues	1
Details	binding site for residue ZN C 302

Chain	Residue
C	HIS40

---

site_id	AC7
Number of Residues	3
Details	binding site for residue IMD C 303

Chain	Residue
C	GLY15
C	HIS65
C	ASN141

---

site_id	AC8
Number of Residues	3
Details	binding site for residue EDO C 304

Chain	Residue
C	ASN122
C	TYR123
C	HOH404

---

site_id	AC9
Number of Residues	5
Details	binding site for residue EDO C 305

Chain	Residue
C	GLN5
C	TYR6
C	HIS106
C	PHE108
C	THR109

---

Functional Information from PROSITE/UniProt

site_id	PS00275
Number of Residues	17
Details	SHIGA_RICIN Shiga/ricin ribosomal inactivating toxins active site signature. IqMIsEAARFQyIEgeM

Chain	Residue	Details
A	ILE172-MET188

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:P84531

Chain	Residue	Details
A	TYR80
A	TYR123
A	GLU177
A	ARG180
C	TYR80
C	TYR123
C	GLU177
C	ARG180

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ILE8
C	ILE8

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING:

Chain	Residue	Details
A	GLY15
A	GLY50
A	ASN141
A	ASN195
C	GLY15
C	GLY50
C	ASN141
C	ASN195

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:8780513, ECO:0007744|PDB:1OBT

Chain	Residue	Details
A	TYR80
A	GLY121
C	TYR80
C	GLY121

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:1368517

Chain	Residue	Details
A	ASN10
C	ASN10

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; partial => ECO:0000269|PubMed:1368517

Chain	Residue	Details
A	ASN236
C	ASN236

---