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6OBP

Reconstituted PP1 holoenzyme

Functional Information from GO Data
ChainGOidnamespacecontents
A0000164cellular_componentprotein phosphatase type 1 complex
A0000781cellular_componentchromosome, telomeric region
A0004721molecular_functionphosphoprotein phosphatase activity
A0004722molecular_functionprotein serine/threonine phosphatase activity
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005730cellular_componentnucleolus
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0005912cellular_componentadherens junction
A0005977biological_processglycogen metabolic process
A0005979biological_processregulation of glycogen biosynthetic process
A0005981biological_processregulation of glycogen catabolic process
A0006446biological_processregulation of translational initiation
A0006470biological_processprotein dephosphorylation
A0008157molecular_functionprotein phosphatase 1 binding
A0010288biological_processresponse to lead ion
A0016311biological_processdephosphorylation
A0016787molecular_functionhydrolase activity
A0016791molecular_functionphosphatase activity
A0017018molecular_functionmyosin phosphatase activity
A0030324biological_processlung development
A0032922biological_processcircadian regulation of gene expression
A0042587cellular_componentglycogen granule
A0042752biological_processregulation of circadian rhythm
A0043021molecular_functionribonucleoprotein complex binding
A0043025cellular_componentneuronal cell body
A0043153biological_processentrainment of circadian clock by photoperiod
A0043197cellular_componentdendritic spine
A0043204cellular_componentperikaryon
A0043247biological_processtelomere maintenance in response to DNA damage
A0044877molecular_functionprotein-containing complex binding
A0046872molecular_functionmetal ion binding
A0048754biological_processbranching morphogenesis of an epithelial tube
A0051301biological_processcell division
A0060828biological_processregulation of canonical Wnt signaling pathway
A0070062cellular_componentextracellular exosome
A0072357cellular_componentPTW/PP1 phosphatase complex
A0098609biological_processcell-cell adhesion
A0098641molecular_functioncadherin binding involved in cell-cell adhesion
A0098793cellular_componentpresynapse
A0098794cellular_componentpostsynapse
A0098978cellular_componentglutamatergic synapse
A2001241biological_processpositive regulation of extrinsic apoptotic signaling pathway in absence of ligand
Functional Information from PDB Data
site_idAC1
Number of Residues7
Detailsbinding site for residue PO4 A 401
ChainResidue
AHIS66
AASP92
AASN124
AHIS125
AARG221
AHIS248
AMN402

site_idAC2
Number of Residues5
Detailsbinding site for residue MN A 402
ChainResidue
AHIS173
AHIS248
APO4401
AASP92
AASN124

site_idAC3
Number of Residues4
Detailsbinding site for residue CL A 403
ChainResidue
ATYR114
APRO115
AGLU116
AASN117

site_idAC4
Number of Residues3
Detailsbinding site for residue CL A 404
ChainResidue
ALEU40
AARG43
AGLU44

site_idAC5
Number of Residues1
Detailsbinding site for residue CL A 405
ChainResidue
AHIS239

site_idAC6
Number of Residues3
Detailsbinding site for residue PO4 C 401
ChainResidue
CARG155
CLYS175
CARG197

Functional Information from PROSITE/UniProt
site_idPS00125
Number of Residues6
DetailsSER_THR_PHOSPHATASE Serine/threonine specific protein phosphatases signature. LRGNHE
ChainResidueDetails
ALEU121-GLU126

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
CSER322

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
AASP64
AHIS66

site_idSWS_FT_FI3
Number of Residues4
DetailsBINDING:
ChainResidueDetails
AASP92
AASN124
AHIS173
AHIS248

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
ASER2
ASER22

221051

PDB entries from 2024-06-12

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