6O98
Crystal structure of RAR-related orphan receptor C in complex with a phenyl (3-phenylpyrrolidin-3-yl)sulfone inhibitor
Replaces: 6NXHFunctional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004879 | molecular_function | nuclear receptor activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue L8A A 601 |
| Chain | Residue |
| A | CYS264 |
| A | ARG346 |
| A | ALA347 |
| A | VAL355 |
| A | PHE357 |
| A | PHE367 |
| A | ILE376 |
| A | ILE379 |
| A | PHE380 |
| A | HIS458 |
| A | LEU462 |
| A | GLN265 |
| A | LEU271 |
| A | TRP296 |
| A | CYS299 |
| A | HIS302 |
| A | LEU303 |
| A | MET337 |
| A | MET344 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | binding site for residue L8A B 601 |
| Chain | Residue |
| B | CYS264 |
| B | LEU271 |
| B | TRP296 |
| B | CYS299 |
| B | HIS302 |
| B | LEU303 |
| B | MET337 |
| B | MET344 |
| B | ARG346 |
| B | ALA347 |
| B | PHE357 |
| B | PHE367 |
| B | ILE376 |
| B | ILE379 |
| B | HIS458 |
| B | LEU462 |
