6O23

Crystal structure of 2243 Fab in complex with circumsporozoite protein NANP5

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue EDO A 301

Chain	Residue
A	ARG16
A	SER17
D	LYS145

---

site_id	AC2
Number of Residues	3
Details	binding site for residue EDO A 302

Chain	Residue
A	GLU46
A	ASP61
A	SER62

---

site_id	AC3
Number of Residues	7
Details	binding site for residue EDO A 303

Chain	Residue
C	TYR52
E	ASN9
E	ALA10
E	ASN11
A	TRP52
A	ASN56
A	TYR58

---

site_id	AC4
Number of Residues	6
Details	binding site for residue EDO A 304

Chain	Residue
A	LEU189
A	THR191
A	GLN192
A	THR193
A	ARG210
A	HOH478

---

site_id	AC5
Number of Residues	7
Details	binding site for residue SO4 A 305

Chain	Residue
A	SER130
A	THR131
A	SER132
A	SER186
A	SER187
A	HOH449
A	HOH502

---

site_id	AC6
Number of Residues	5
Details	binding site for residue SO4 A 306

Chain	Residue
A	SER25
A	GLY26
C	SER187
C	HOH472
C	HOH489

---

site_id	AC7
Number of Residues	4
Details	binding site for residue SO4 A 307

Chain	Residue
A	PHE27
A	THR28
A	TYR32
A	HOH432

---

site_id	AC8
Number of Residues	4
Details	binding site for residue EDO B 301

Chain	Residue
B	SER121
B	ASP122
B	GLU123
B	HOH401

---

site_id	AC9
Number of Residues	3
Details	binding site for residue EDO B 302

Chain	Residue
B	LYS190
B	ASN210
B	GLY212

---

site_id	AD1
Number of Residues	3
Details	binding site for residue SO4 B 303

Chain	Residue
B	PRO59
B	ARG61
B	ASP81

---

site_id	AD2
Number of Residues	5
Details	binding site for residue EDO C 301

Chain	Residue
B	SER93
C	ASP97
C	ALA99
E	ASN11
E	ASN13

---

site_id	AD3
Number of Residues	7
Details	binding site for residue EDO C 302

Chain	Residue
C	LEU96
C	ASP97
C	ASP98
C	SER100
C	CYS100
E	ASN7
E	ASN9

---

site_id	AD4
Number of Residues	8
Details	binding site for residue EDO C 303

Chain	Residue
C	LEU141
C	VAL169
C	SER177
C	LEU178
C	HOH462
D	THR178
D	HOH440
D	HOH478

---

site_id	AD5
Number of Residues	5
Details	binding site for residue SO4 C 304

Chain	Residue
C	ASN155
C	GLN192
C	HOH431
C	HOH475
C	HOH499

---

site_id	AD6
Number of Residues	5
Details	binding site for residue TRS D 301

Chain	Residue
A	ARG16
D	PRO8
D	SER9
D	THR10
D	GLU143

---

site_id	AD7
Number of Residues	7
Details	binding site for residue EDO D 302

Chain	Residue
D	GLN37
D	LYS45
D	ARG61
D	PHE62
D	ASP81
D	ASP82
D	HOH424

---

site_id	AD8
Number of Residues	4
Details	binding site for residue EDO D 303

Chain	Residue
D	SER156
D	GLY157
D	HOH430
D	HOH514

---

site_id	AD9
Number of Residues	5
Details	binding site for residue EDO D 304

Chain	Residue
D	ASP105
D	GLN166
D	HOH459
D	HOH473
D	HOH479

---

site_id	AE1
Number of Residues	4
Details	binding site for residue SO4 D 305

Chain	Residue
D	PRO59
D	ARG61
D	ASP81
D	HOH415

---

site_id	AE2
Number of Residues	4
Details	binding site for residue SO4 D 306

Chain	Residue
D	ARG142
D	VAL163
D	GLU165
D	HOH404

---

site_id	AE3
Number of Residues	1
Details	binding site for residue SO4 D 307

Chain	Residue
D	ASP1

---

site_id	AE4
Number of Residues	5
Details	binding site for residue SO4 D 308

Chain	Residue
D	SER67
D	GLY68
D	THR69
D	GLU70
D	HOH444

---

site_id	AE5
Number of Residues	6
Details	binding site for residue EDO E 101

Chain	Residue
A	SER31
A	TYR32
A	ASP97
E	ASN17
E	ALA18
E	ASN19

---

site_id	AE6
Number of Residues	7
Details	binding site for residue SO4 E 102

Chain	Residue
E	ASN7
E	ASN11
E	ALA14
E	HOH206
E	HOH209
E	HOH210
E	HOH214

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
B	TYR192-HIS198
A	TYR194-HIS200

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Repeat: {"description":"38","evidences":[{"source":"PubMed","id":"6204383","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Repeat: {"description":"39","evidences":[{"source":"PubMed","id":"6204383","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Repeat: {"description":"40","evidences":[{"source":"PubMed","id":"6204383","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	Repeat: {"description":"41","evidences":[{"source":"PubMed","id":"6204383","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	Repeat: {"description":"39","evidences":[{"source":"PubMed","id":"2671723","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	3
Details	Repeat: {"description":"40","evidences":[{"source":"PubMed","id":"2671723","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	3
Details	Repeat: {"description":"41","evidences":[{"source":"PubMed","id":"2671723","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	3
Details	Repeat: {"description":"42","evidences":[{"source":"PubMed","id":"2671723","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---