6NZT

Crystal structure of HCV NS3/4A protease in complex with voxilaprevir

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006508	biological_process	proteolysis
A	0008236	molecular_function	serine-type peptidase activity
A	0019087	biological_process	transformation of host cell by virus

Functional Information from PDB Data

site_id	AC1
Number of Residues	22
Details	binding site for residue L9P A 1201

Chain	Residue
A	GLN1041
A	GLY1137
A	SER1138
A	SER1139
A	PHE1154
A	ARG1155
A	ALA1156
A	ALA1157
A	SO41203
A	HOH1321
A	HOH1364
A	THR1042
A	HOH1379
A	HOH1400
A	HOH1410
A	PHE1043
A	TYR1056
A	HIS1057
A	ASP1081
A	ILE1132
A	LEU1135
A	LYS1136

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site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 1202

Chain	Residue
A	CYS1097
A	CYS1099
A	CYS1145
A	HIS1149

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site_id	AC3
Number of Residues	6
Details	binding site for residue SO4 A 1203

Chain	Residue
A	TYR1006
A	GLN1008
A	TYR1056
A	L9P1201
A	HOH1370
A	HOH1373

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