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6NXW

Crystal structure of Arabidopsis thaliana cytosolic triosephosphate isomerase C218S mutant

Functional Information from GO Data
ChainGOidnamespacecontents
A0000325cellular_componentplant-type vacuole
A0004807molecular_functiontriose-phosphate isomerase activity
A0005507molecular_functioncopper ion binding
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005794cellular_componentGolgi apparatus
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0005975biological_processcarbohydrate metabolic process
A0006094biological_processgluconeogenesis
A0006096biological_processglycolytic process
A0009505cellular_componentplant-type cell wall
A0009506cellular_componentplasmodesma
A0009507cellular_componentchloroplast
A0009570cellular_componentchloroplast stroma
A0010043biological_processresponse to zinc ion
A0016052biological_processcarbohydrate catabolic process
A0016853molecular_functionisomerase activity
A0019563biological_processglycerol catabolic process
A0046166biological_processglyceraldehyde-3-phosphate biosynthetic process
A0048046cellular_componentapoplast
B0000325cellular_componentplant-type vacuole
B0004807molecular_functiontriose-phosphate isomerase activity
B0005507molecular_functioncopper ion binding
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005794cellular_componentGolgi apparatus
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0005975biological_processcarbohydrate metabolic process
B0006094biological_processgluconeogenesis
B0006096biological_processglycolytic process
B0009505cellular_componentplant-type cell wall
B0009506cellular_componentplasmodesma
B0009507cellular_componentchloroplast
B0009570cellular_componentchloroplast stroma
B0010043biological_processresponse to zinc ion
B0016052biological_processcarbohydrate catabolic process
B0016853molecular_functionisomerase activity
B0019563biological_processglycerol catabolic process
B0046166biological_processglyceraldehyde-3-phosphate biosynthetic process
B0048046cellular_componentapoplast
C0000325cellular_componentplant-type vacuole
C0004807molecular_functiontriose-phosphate isomerase activity
C0005507molecular_functioncopper ion binding
C0005737cellular_componentcytoplasm
C0005739cellular_componentmitochondrion
C0005794cellular_componentGolgi apparatus
C0005829cellular_componentcytosol
C0005886cellular_componentplasma membrane
C0005975biological_processcarbohydrate metabolic process
C0006094biological_processgluconeogenesis
C0006096biological_processglycolytic process
C0009505cellular_componentplant-type cell wall
C0009506cellular_componentplasmodesma
C0009507cellular_componentchloroplast
C0009570cellular_componentchloroplast stroma
C0010043biological_processresponse to zinc ion
C0016052biological_processcarbohydrate catabolic process
C0016853molecular_functionisomerase activity
C0019563biological_processglycerol catabolic process
C0046166biological_processglyceraldehyde-3-phosphate biosynthetic process
C0048046cellular_componentapoplast
D0000325cellular_componentplant-type vacuole
D0004807molecular_functiontriose-phosphate isomerase activity
D0005507molecular_functioncopper ion binding
D0005737cellular_componentcytoplasm
D0005739cellular_componentmitochondrion
D0005794cellular_componentGolgi apparatus
D0005829cellular_componentcytosol
D0005886cellular_componentplasma membrane
D0005975biological_processcarbohydrate metabolic process
D0006094biological_processgluconeogenesis
D0006096biological_processglycolytic process
D0009505cellular_componentplant-type cell wall
D0009506cellular_componentplasmodesma
D0009507cellular_componentchloroplast
D0009570cellular_componentchloroplast stroma
D0010043biological_processresponse to zinc ion
D0016052biological_processcarbohydrate catabolic process
D0016853molecular_functionisomerase activity
D0019563biological_processglycerol catabolic process
D0046166biological_processglyceraldehyde-3-phosphate biosynthetic process
D0048046cellular_componentapoplast
Functional Information from PROSITE/UniProt
site_idPS00171
Number of Residues11
DetailsTIM_1 Triosephosphate isomerase active site. AYEPVWAIGTG
ChainResidueDetails
AALA164-GLY174

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsACT_SITE: Electrophile => ECO:0000250
ChainResidueDetails
AHIS96
BHIS96
CHIS96
DHIS96

site_idSWS_FT_FI2
Number of Residues4
DetailsACT_SITE: Proton acceptor => ECO:0000250
ChainResidueDetails
AGLU166
BGLU166
CGLU166
DGLU166

site_idSWS_FT_FI3
Number of Residues8
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
AASN10
ALYS12
BASN10
BLYS12
CASN10
CLYS12
DASN10
DLYS12

site_idSWS_FT_FI4
Number of Residues4
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:22092075
ChainResidueDetails
ATHR131
BTHR131
CTHR131
DTHR131

site_idSWS_FT_FI5
Number of Residues4
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:22092075
ChainResidueDetails
ASER139
BSER139
CSER139
DSER139

237735

PDB entries from 2025-06-18

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