6NUQ

Stat3 Core in complex with compound SI109

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
A	0007165	biological_process	signal transduction

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	binding site for residue KQV A 701

Chain	Residue
A	ASP173
A	SER636
A	VAL637
A	GLU638
A	PRO639
A	TYR640
A	GLN644
A	TYR657
A	LYS658
A	ILE659
A	LEU666
A	TYR176
A	LYS290
A	SER292
A	ARG609
A	SER611
A	GLU612
A	SER613
A	THR620

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0000269|PubMed:28065600

Chain	Residue	Details
A	LYS601
A	LYS615
A	LYS631

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0000269|PubMed:15653507, ECO:0000269|PubMed:28065600

Chain	Residue	Details
A	LYS685

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