Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6NT0

Catalase 3 from N.Crassa in ferrous state, X-ray reduced (1.315 MGy)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004096	molecular_function	catalase activity
A	0006979	biological_process	response to oxidative stress
A	0020037	molecular_function	heme binding
B	0004096	molecular_function	catalase activity
B	0006979	biological_process	response to oxidative stress
B	0020037	molecular_function	heme binding
C	0004096	molecular_function	catalase activity
C	0006979	biological_process	response to oxidative stress
C	0020037	molecular_function	heme binding
D	0004096	molecular_function	catalase activity
D	0006979	biological_process	response to oxidative stress
D	0020037	molecular_function	heme binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	24
Details	binding site for residue HEM A 801

Chain	Residue
A	ARG99
A	PHE180
A	PHE188
A	ILE248
A	HIS249
A	PHE365
A	LEU381
A	ARG385
A	SER388
A	TYR389
A	THR392
A	VAL100
A	GLN393
A	ARG396
A	HOH966
A	HOH969
A	HOH972
A	VAL101
A	HIS102
A	ARG139
A	GLY158
A	VAL173
A	GLY174
A	ASN175

site_id	AC2
Number of Residues	6
Details	binding site for residue ACT A 802

Chain	Residue
A	VAL143
A	ALA144
A	ASP155
A	VAL156
A	PHE181
A	VAL195

site_id	AC3
Number of Residues	8
Details	binding site for residue ACT A 803

Chain	Residue
A	ASN176
A	ASN234
A	PRO237
A	HIS242
A	MET243
A	LYS273
A	ALA274
A	HOH919

site_id	AC4
Number of Residues	4
Details	binding site for residue PGE A 804

Chain	Residue
A	GLN612
A	ALA621
A	HOH1097
A	HOH1183

site_id	AC5
Number of Residues	3
Details	binding site for residue PEG A 805

Chain	Residue
A	ASP477
A	TYR547
D	GLN542

site_id	AC6
Number of Residues	5
Details	binding site for residue PEG A 806

Chain	Residue
A	TYR438
A	LEU439
A	LYS441
D	ASN551
D	EOH809

site_id	AC7
Number of Residues	3
Details	binding site for residue EDO A 807

Chain	Residue
A	ASN551
A	VAL552
A	HOH1012

site_id	AC8
Number of Residues	1
Details	binding site for residue EOH A 808

Chain	Residue
A	GLU317

site_id	AC9
Number of Residues	24
Details	binding site for residue HEM B 801

Chain	Residue
B	ARG99
B	VAL100
B	VAL101
B	HIS102
B	ARG139
B	GLY158
B	VAL173
B	GLY174
B	ASN175
B	PHE188
B	ILE248
B	HIS249
B	PHE365
B	LEU381
B	ARG385
B	SER388
B	TYR389
B	THR392
B	GLN393
B	ARG396
B	HOH951
B	HOH957
B	HOH1063
B	HOH1284

site_id	AD1
Number of Residues	6
Details	binding site for residue ACT B 802

Chain	Residue
B	VAL143
B	ALA144
B	ASP155
B	VAL156
B	PHE181
B	VAL195

site_id	AD2
Number of Residues	7
Details	binding site for residue ACT B 803

Chain	Residue
B	ASN176
B	PRO237
B	HIS242
B	MET243
B	LYS273
B	ALA274
B	HOH905

site_id	AD3
Number of Residues	4
Details	binding site for residue PGE B 804

Chain	Residue
B	THR600
B	GLN612
B	ALA621
B	HOH970

site_id	AD4
Number of Residues	6
Details	binding site for residue PEG B 805

Chain	Residue
B	HOH1198
C	P6G811
B	THR655
B	TYR658
B	ARG659
B	ILE677

site_id	AD5
Number of Residues	2
Details	binding site for residue EDO B 806

Chain	Residue
B	TYR438
B	LYS441

site_id	AD6
Number of Residues	3
Details	binding site for residue EDO B 807

Chain	Residue
B	ASN551
B	VAL552
B	HOH1245

site_id	AD7
Number of Residues	3
Details	binding site for residue EOH B 808

Chain	Residue
B	ARG252
B	GLU317
B	GLY460

site_id	AD8
Number of Residues	23
Details	binding site for residue HEM C 801

Chain	Residue
C	ARG99
C	VAL100
C	VAL101
C	HIS102
C	ARG139
C	GLY158
C	VAL173
C	GLY174
C	ASN175
C	PHE188
C	ILE248
C	HIS249
C	PHE365
C	LEU381
C	ARG385
C	SER388
C	TYR389
C	THR392
C	GLN393
C	ARG396
C	HOH945
C	HOH956
C	HOH1059

site_id	AD9
Number of Residues	6
Details	binding site for residue ACT C 802

Chain	Residue
C	VAL143
C	ALA144
C	ASP155
C	VAL156
C	PHE181
C	VAL195

site_id	AE1
Number of Residues	7
Details	binding site for residue ACT C 803

Chain	Residue
C	ASN176
C	ASN234
C	PRO237
C	HIS242
C	LYS273
C	ALA274
C	HOH947

site_id	AE2
Number of Residues	5
Details	binding site for residue PG4 C 804

Chain	Residue
B	TYR115
C	TRP118
C	LEU341
C	GLN342
C	HOH1209

site_id	AE3
Number of Residues	3
Details	binding site for residue PGE C 805

Chain	Residue
B	ASP117
B	SER119
C	ARG554

site_id	AE4
Number of Residues	1
Details	binding site for residue PEG C 806

Chain	Residue
C	GLY324

site_id	AE5
Number of Residues	4
Details	binding site for residue PEG C 807

Chain	Residue
C	ARG570
C	THR600
C	ASP611
C	GLN612

site_id	AE6
Number of Residues	2
Details	binding site for residue EDO C 808

Chain	Residue
C	ARG409
C	VAL414

site_id	AE7
Number of Residues	4
Details	binding site for residue EDO C 809

Chain	Residue
C	SER198
C	ASP200
C	ASN201
D	ILE431

site_id	AE8
Number of Residues	2
Details	binding site for residue EDO C 810

Chain	Residue
C	THR546
C	HOH901

site_id	AE9
Number of Residues	10
Details	binding site for residue P6G C 811

Chain	Residue
B	ALA640
B	SER651
B	GLN652
B	ARG659
B	PEG805
C	PHE635
C	MET641
C	SER651
C	GLN652
C	ARG659

site_id	AF1
Number of Residues	25
Details	binding site for residue HEM D 801

Chain	Residue
D	ARG99
D	VAL100
D	VAL101
D	HIS102
D	ARG139
D	GLY158
D	VAL173
D	GLY174
D	ASN175
D	PHE180
D	PHE188
D	ILE248
D	HIS249
D	PHE365
D	LEU381
D	ARG385
D	SER388
D	TYR389
D	THR392
D	GLN393
D	ARG396
D	HOH912
D	HOH964
D	HOH1049
D	HOH1266

site_id	AF2
Number of Residues	6
Details	binding site for residue ACT D 802

Chain	Residue
D	VAL143
D	ALA144
D	ASP155
D	VAL156
D	PHE181
D	VAL195

site_id	AF3
Number of Residues	8
Details	binding site for residue ACT D 803

Chain	Residue
D	ASN176
D	ASN234
D	PRO237
D	HIS242
D	LYS273
D	ALA274
D	ILE558
D	HOH922

site_id	AF4
Number of Residues	4
Details	binding site for residue PGE D 804

Chain	Residue
A	SER651
A	ARG659
D	GLN652
D	ARG659

site_id	AF5
Number of Residues	3
Details	binding site for residue EDO D 805

Chain	Residue
D	TYR438
D	LEU439
D	LYS441

site_id	AF6
Number of Residues	4
Details	binding site for residue EDO D 806

Chain	Residue
D	GLN321
D	PHE325
D	THR474
D	HOH923

site_id	AF7
Number of Residues	2
Details	binding site for residue EOH D 807

Chain	Residue
B	GLU45
D	ARG409

site_id	AF8
Number of Residues	2
Details	binding site for residue EOH D 808

Chain	Residue
D	ASN551
D	EOH809

site_id	AF9
Number of Residues	5
Details	binding site for residue EOH D 809

Chain	Residue
A	LYS441
A	PEG806
D	GLU337
D	VAL552
D	EOH808

site_id	AG1
Number of Residues	2
Details	binding site for residue EOH D 810

Chain	Residue
D	ARG659
D	ILE677

Functional Information from PROSITE/UniProt

site_id	PS00438
Number of Residues	17
Details	CATALASE_2 Catalase proximal active site signature. FdHeripERvvHarGAG

Chain	Residue	Details
A	PHE91-GLY107

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: ACT_SITE => ECO:0000255\|PROSITE-ProRule:PRU10013

Chain	Residue	Details
A	HIS102
A	ASN175
B	HIS102
B	ASN175
C	HIS102
C	ASN175
D	HIS102
D	ASN175

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: axial binding residue => ECO:0000250

Chain	Residue	Details
A	TYR389
B	TYR389
C	TYR389
D	TYR389

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)