6NST

Crystal structure of branched chain amino acid aminotransferase from Pseudomonas aeruginosa

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004084	molecular_function	branched-chain-amino-acid:2-oxoglutarate transaminase activity
A	0005829	cellular_component	cytosol
A	0006532	biological_process	L-aspartate biosynthetic process
A	0009081	biological_process	branched-chain amino acid metabolic process
A	0009098	biological_process	L-leucine biosynthetic process
A	0009099	biological_process	L-valine biosynthetic process
A	0046394	biological_process	carboxylic acid biosynthetic process
A	0052654	molecular_function	L-leucine:2-oxoglutarate transaminase activity
A	0052655	molecular_function	L-valine:2-oxoglutarate transaminase activity
A	0052656	molecular_function	L-isoleucine:2-oxoglutarate transaminase activity
B	0003824	molecular_function	catalytic activity
B	0004084	molecular_function	branched-chain-amino-acid:2-oxoglutarate transaminase activity
B	0005829	cellular_component	cytosol
B	0006532	biological_process	L-aspartate biosynthetic process
B	0009081	biological_process	branched-chain amino acid metabolic process
B	0009098	biological_process	L-leucine biosynthetic process
B	0009099	biological_process	L-valine biosynthetic process
B	0046394	biological_process	carboxylic acid biosynthetic process
B	0052654	molecular_function	L-leucine:2-oxoglutarate transaminase activity
B	0052655	molecular_function	L-valine:2-oxoglutarate transaminase activity
B	0052656	molecular_function	L-isoleucine:2-oxoglutarate transaminase activity
C	0003824	molecular_function	catalytic activity
C	0004084	molecular_function	branched-chain-amino-acid:2-oxoglutarate transaminase activity
C	0005829	cellular_component	cytosol
C	0006532	biological_process	L-aspartate biosynthetic process
C	0009081	biological_process	branched-chain amino acid metabolic process
C	0009098	biological_process	L-leucine biosynthetic process
C	0009099	biological_process	L-valine biosynthetic process
C	0046394	biological_process	carboxylic acid biosynthetic process
C	0052654	molecular_function	L-leucine:2-oxoglutarate transaminase activity
C	0052655	molecular_function	L-valine:2-oxoglutarate transaminase activity
C	0052656	molecular_function	L-isoleucine:2-oxoglutarate transaminase activity
D	0003824	molecular_function	catalytic activity
D	0004084	molecular_function	branched-chain-amino-acid:2-oxoglutarate transaminase activity
D	0005829	cellular_component	cytosol
D	0006532	biological_process	L-aspartate biosynthetic process
D	0009081	biological_process	branched-chain amino acid metabolic process
D	0009098	biological_process	L-leucine biosynthetic process
D	0009099	biological_process	L-valine biosynthetic process
D	0046394	biological_process	carboxylic acid biosynthetic process
D	0052654	molecular_function	L-leucine:2-oxoglutarate transaminase activity
D	0052655	molecular_function	L-valine:2-oxoglutarate transaminase activity
D	0052656	molecular_function	L-isoleucine:2-oxoglutarate transaminase activity
E	0003824	molecular_function	catalytic activity
E	0004084	molecular_function	branched-chain-amino-acid:2-oxoglutarate transaminase activity
E	0005829	cellular_component	cytosol
E	0006532	biological_process	L-aspartate biosynthetic process
E	0009081	biological_process	branched-chain amino acid metabolic process
E	0009098	biological_process	L-leucine biosynthetic process
E	0009099	biological_process	L-valine biosynthetic process
E	0046394	biological_process	carboxylic acid biosynthetic process
E	0052654	molecular_function	L-leucine:2-oxoglutarate transaminase activity
E	0052655	molecular_function	L-valine:2-oxoglutarate transaminase activity
E	0052656	molecular_function	L-isoleucine:2-oxoglutarate transaminase activity
F	0003824	molecular_function	catalytic activity
F	0004084	molecular_function	branched-chain-amino-acid:2-oxoglutarate transaminase activity
F	0005829	cellular_component	cytosol
F	0006532	biological_process	L-aspartate biosynthetic process
F	0009081	biological_process	branched-chain amino acid metabolic process
F	0009098	biological_process	L-leucine biosynthetic process
F	0009099	biological_process	L-valine biosynthetic process
F	0046394	biological_process	carboxylic acid biosynthetic process
F	0052654	molecular_function	L-leucine:2-oxoglutarate transaminase activity
F	0052655	molecular_function	L-valine:2-oxoglutarate transaminase activity
F	0052656	molecular_function	L-isoleucine:2-oxoglutarate transaminase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue SO4 A 401

Chain	Residue
A	ARG61
A	GLY219
A	ILE220
A	THR221
A	GLY256
A	THR257
A	HOH513
A	HOH541

---

site_id	AC2
Number of Residues	8
Details	binding site for residue SO4 B 401

Chain	Residue
B	GLY219
B	ILE220
B	THR221
B	THR257
B	HOH508
B	HOH510
B	HOH544
B	ARG61

---

site_id	AC3
Number of Residues	7
Details	binding site for residue SO4 C 401

Chain	Residue
C	ARG61
C	GLY219
C	ILE220
C	THR221
C	THR257
C	HOH507
C	HOH509

---

site_id	AC4
Number of Residues	6
Details	binding site for residue SO4 D 401

Chain	Residue
D	ARG61
D	GLY219
D	ILE220
D	THR221
D	THR257
D	HOH512

---

site_id	AC5
Number of Residues	8
Details	binding site for residue SO4 E 401

Chain	Residue
E	ARG61
E	GLY219
E	ILE220
E	THR221
E	GLY256
E	THR257
E	HOH514
E	HOH523

---

site_id	AC6
Number of Residues	9
Details	binding site for residue SO4 F 401

Chain	Residue
F	ARG61
F	GLY219
F	ILE220
F	THR221
F	GLY256
F	THR257
F	HOH513
F	HOH524
F	HOH534

---

Functional Information from PROSITE/UniProt

site_id	PS00770
Number of Residues	29
Details	AA_TRANSFER_CLASS_4 Aminotransferases class-IV signature. EgSgeNIFiikdgv......IyTpevtac..LnGItR

Chain	Residue	Details
A	GLU194-ARG222

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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