Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6NQB

Role of Era in Assembly and Homeostasis of the Ribosomal Small Subunit

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000028	biological_process	ribosomal small subunit assembly
B	0002181	biological_process	cytoplasmic translation
B	0003735	molecular_function	structural constituent of ribosome
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005840	cellular_component	ribosome
B	0006412	biological_process	translation
B	0008270	molecular_function	zinc ion binding
B	0015935	cellular_component	small ribosomal subunit
B	0022627	cellular_component	cytosolic small ribosomal subunit
B	1990904	cellular_component	ribonucleoprotein complex
C	0003676	molecular_function	nucleic acid binding
C	0003723	molecular_function	RNA binding
C	0003735	molecular_function	structural constituent of ribosome
C	0006412	biological_process	translation
D	0000028	biological_process	ribosomal small subunit assembly
D	0000900	molecular_function	mRNA regulatory element binding translation repressor activity
D	0002181	biological_process	cytoplasmic translation
D	0003723	molecular_function	RNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005840	cellular_component	ribosome
D	0006353	biological_process	DNA-templated transcription termination
D	0006412	biological_process	translation
D	0006417	biological_process	regulation of translation
D	0015935	cellular_component	small ribosomal subunit
D	0019843	molecular_function	rRNA binding
D	0022627	cellular_component	cytosolic small ribosomal subunit
D	0031564	biological_process	transcription antitermination
D	0042254	biological_process	ribosome biogenesis
D	0042274	biological_process	ribosomal small subunit biogenesis
D	0045947	biological_process	negative regulation of translational initiation
D	0046677	biological_process	response to antibiotic
D	0048027	molecular_function	mRNA 5'-UTR binding
D	1990145	biological_process	maintenance of translational fidelity
D	1990904	cellular_component	ribonucleoprotein complex
E	0003723	molecular_function	RNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0015935	cellular_component	small ribosomal subunit
F	0003735	molecular_function	structural constituent of ribosome
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0019843	molecular_function	rRNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
J	0000049	molecular_function	tRNA binding
J	0001072	molecular_function	transcription antitermination factor activity, RNA binding
J	0002181	biological_process	cytoplasmic translation
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005515	molecular_function	protein binding
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0008023	cellular_component	transcription elongation factor complex
J	0015935	cellular_component	small ribosomal subunit
J	0022627	cellular_component	cytosolic small ribosomal subunit
J	0031564	biological_process	transcription antitermination
J	0032784	biological_process	regulation of DNA-templated transcription elongation
J	0042254	biological_process	ribosome biogenesis
J	1990904	cellular_component	ribonucleoprotein complex
L	0003735	molecular_function	structural constituent of ribosome
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0015935	cellular_component	small ribosomal subunit
N	0000028	biological_process	ribosomal small subunit assembly
N	0000049	molecular_function	tRNA binding
N	0002181	biological_process	cytoplasmic translation
N	0003735	molecular_function	structural constituent of ribosome
N	0005737	cellular_component	cytoplasm
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0015935	cellular_component	small ribosomal subunit
N	0019843	molecular_function	rRNA binding
N	0022627	cellular_component	cytosolic small ribosomal subunit
N	1990904	cellular_component	ribonucleoprotein complex
O	0000028	biological_process	ribosomal small subunit assembly
O	0002181	biological_process	cytoplasmic translation
O	0003723	molecular_function	RNA binding
O	0003735	molecular_function	structural constituent of ribosome
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0006417	biological_process	regulation of translation
O	0019843	molecular_function	rRNA binding
O	0022627	cellular_component	cytosolic small ribosomal subunit
O	0070181	molecular_function	small ribosomal subunit rRNA binding
O	1990904	cellular_component	ribonucleoprotein complex
P	0000028	biological_process	ribosomal small subunit assembly
P	0000400	molecular_function	four-way junction DNA binding
P	0002181	biological_process	cytoplasmic translation
P	0003735	molecular_function	structural constituent of ribosome
P	0004518	molecular_function	nuclease activity
P	0004519	molecular_function	endonuclease activity
P	0004520	molecular_function	DNA endonuclease activity
P	0005737	cellular_component	cytoplasm
P	0005840	cellular_component	ribosome
P	0006259	biological_process	DNA metabolic process
P	0006412	biological_process	translation
P	0015935	cellular_component	small ribosomal subunit
P	0016787	molecular_function	hydrolase activity
P	0022627	cellular_component	cytosolic small ribosomal subunit
P	1990904	cellular_component	ribonucleoprotein complex
Q	0000028	biological_process	ribosomal small subunit assembly
Q	0002181	biological_process	cytoplasmic translation
Q	0003723	molecular_function	RNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005737	cellular_component	cytoplasm
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0008270	molecular_function	zinc ion binding
Q	0019843	molecular_function	rRNA binding
Q	0022627	cellular_component	cytosolic small ribosomal subunit
Q	0046677	biological_process	response to antibiotic
Q	0070181	molecular_function	small ribosomal subunit rRNA binding
Q	1990904	cellular_component	ribonucleoprotein complex
R	0003735	molecular_function	structural constituent of ribosome
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0015935	cellular_component	small ribosomal subunit
T	0000028	biological_process	ribosomal small subunit assembly
T	0002181	biological_process	cytoplasmic translation
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0008073	molecular_function	ornithine decarboxylase inhibitor activity
T	0015935	cellular_component	small ribosomal subunit
T	0019843	molecular_function	rRNA binding
T	0022627	cellular_component	cytosolic small ribosomal subunit
T	0070181	molecular_function	small ribosomal subunit rRNA binding
T	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GiaVVSTSkGVMtdraAR

Chain	Residue	Details
H	GLY99-ARG116

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAlR

Chain	Residue	Details
L	LYS42-ARG49

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDvVeIrEcRPLS

Chain	Residue	Details
Q	GLY55-SER67

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGRqhvpvfVtdemVGhkLGEFapT

Chain	Residue	Details
S	ASN52-THR76

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. AkrtGAqvrGPIpLPT

Chain	Residue	Details
J	ALA29-THR44

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. LqgHFaehKkDhhSrrgLlrMvsqrrkLldY

Chain	Residue	Details
O	LEU38-TYR68

site_id	PS00527
Number of Residues	23
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. R.CrqtgrphgflrkFGLSRiKVR

Chain	Residue	Details
N	ARG62-ARG84

site_id	PS00548
Number of Residues	35
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. ARtewyreGrVplHt..LradIDyntseahTtyGviG

Chain	Residue	Details
C	ALA162-GLY196

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GRifsFtAltVVGDgn.GrVGfGygkar.EVpa.AI

Chain	Residue	Details
E	GLY27-ILE59

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LEgRLdnvVYRmgfGaTraeARqLV

Chain	Residue	Details
D	LEU93-VAL117

site_id	PS00732
Number of Residues	10
Details	RIBOSOMAL_S16 Ribosomal protein S16 signature. VtIRLARHGA

Chain	Residue	Details
P	VAL2-ALA11

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PdaLFViDadhEhiaIkEannlGIP

Chain	Residue	Details
B	PRO157-PRO181

site_id	PS01048
Number of Residues	10
Details	RIBOSOMAL_S6 Ribosomal protein S6 signature. GrRQLAYpIN

Chain	Residue	Details
F	GLY43-ASN52

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	68
Details	Domain: {"description":"KH type-2"}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	60
Details	Domain: {"description":"S4 RNA-binding"}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	63
Details	Domain: {"description":"S5 DRBM"}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"18723842","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"PubMed","id":"21151122","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)