6NPK
Structure of the TM domain
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0015377 | molecular_function | chloride:monoatomic cation symporter activity |
| A | 0016020 | cellular_component | membrane |
| A | 0022857 | molecular_function | transmembrane transporter activity |
| A | 0055085 | biological_process | transmembrane transport |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0015377 | molecular_function | chloride:monoatomic cation symporter activity |
| B | 0016020 | cellular_component | membrane |
| B | 0022857 | molecular_function | transmembrane transporter activity |
| B | 0055085 | biological_process | transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 86 |
| Details | TRANSMEM: Discontinuously helical => ECO:0000305|PubMed:31367042 |
| Chain | Residue | Details |
| A | ILE210-GLY235 | |
| A | SER410-ILE428 | |
| B | ILE210-GLY235 | |
| B | SER410-ILE428 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 60 |
| Details | INTRAMEM: Helical => ECO:0000305|PubMed:31367042 |
| Chain | Residue | Details |
| A | ILE210-ILE221 | |
| A | MET230-GLY235 | |
| A | SER410-ALA419 | |
| A | ILE422-ASN427 | |
| B | ILE210-ILE221 | |
| B | MET230-GLY235 | |
| B | SER410-ALA419 | |
| B | ILE422-ASN427 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | INTRAMEM: INTRAMEM => ECO:0000305|PubMed:31367042 |
| Chain | Residue | Details |
| A | TRP222-ARG229 | |
| A | THR420-GLY421 | |
| B | TRP222-ARG229 | |
| B | THR420-GLY421 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 208 |
| Details | TOPO_DOM: Extracellular => ECO:0000305|PubMed:31367042 |
| Chain | Residue | Details |
| A | GLN236-GLY238 | |
| B | CYS464-PHE524 | |
| B | LEU592-ALA594 | |
| B | ASN656 | |
| A | SER320-GLN327 | |
| A | ILE377-PHE409 | |
| A | CYS464-PHE524 | |
| A | LEU592-ALA594 | |
| A | ASN656 | |
| B | GLN236-GLY238 | |
| B | SER320-GLN327 | |
| B | ILE377-PHE409 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 488 |
| Details | TRANSMEM: Helical => ECO:0000305|PubMed:31367042 |
| Chain | Residue | Details |
| A | ILE239-ALA264 | |
| A | TRP657-VAL674 | |
| B | ILE239-ALA264 | |
| B | PRO284-ASP319 | |
| B | THR328-ALA348 | |
| B | GLU351-PHE376 | |
| B | ASP434-ALA463 | |
| B | SER525-CYS555 | |
| B | PRO576-ILE591 | |
| B | GLU595-ASN625 | |
| B | ASN637-ILE655 | |
| A | PRO284-ASP319 | |
| B | TRP657-VAL674 | |
| A | THR328-ALA348 | |
| A | GLU351-PHE376 | |
| A | ASP434-ALA463 | |
| A | SER525-CYS555 | |
| A | PRO576-ILE591 | |
| A | GLU595-ASN625 | |
| A | ASN637-ILE655 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 106 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:31367042 |
| Chain | Residue | Details |
| A | THR265-GLY283 | |
| B | SER626-TYR636 | |
| A | GLY349-MET350 | |
| A | ILE428-ALA433 | |
| A | LYS556-GLU575 | |
| A | SER626-TYR636 | |
| B | THR265-GLY283 | |
| B | GLY349-MET350 | |
| B | ILE428-ALA433 | |
| B | LYS556-GLU575 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498 |
| Chain | Residue | Details |
| A | ASN475 | |
| A | ASN481 | |
| B | ASN475 | |
| B | ASN481 |
